Artifact reduction in multichannel pervasive EEG using hybrid WPT-ICA and WPT-EMD signal decomposition techniques

This is the author accepted manuscript. The final version is available from IEEE via the DOI in this record.In order to reduce the muscle artifacts in multi-channel pervasive Electroencephalogram (EEG) signals, we here propose and compare two hybrid algorithms by combining the concept of wavelet packet transform (WPT), empirical mode decomposition (EMD) and Independent Component Analysis (ICA). The signal cleaning performances of WPT-EMD and WPT-ICA algorithms have been compared using a signal-to-noise ratio (SNR)-like criterion for artifacts. The algorithms have been tested on multiple trials of four different artifact cases viz. eye-blinking and muscle artifacts including left and right hand movement and head-shaking.This work was supported by FP7 EU funded MICHELANGELO project, Grant Agreement #288241

EEG signals analysis using multiscale entropy for depth of anesthesia monitoring during surgery through artificial neural networks

In order to build a reliable index to monitor the depth of anesthesia (DOA), many algorithms have been proposed in recent years, one of which is sample entropy (SampEn), a commonly used and important tool to measure the regularity of data series. However, SampEn only estimates the complexity of signals on one time scale. In this study, a new approach is introduced using multiscale entropy (MSE) considering the structure information over different time scales. The entropy values over different time scales calculated through MSE are applied as the input data to train an artificial neural network (ANN) model using bispectral index (BIS) or expert assessment of conscious level (EACL) as the target. To test the performance of the new index's sensitivity to artifacts, we compared the results before and after filtration by multivariate empirical mode decomposition (MEMD). The new approach via ANN is utilized in real EEG signals collected from 26 patients before and after filtering by MEMD, respectively; the results show that is a higher correlation between index from the proposed approach and the gold standard compared with SampEn. Moreover, the proposed approach is more structurally robust to noise and artifacts which indicates that it can be used for monitoring the DOA more accurately.This research was financially supported by the Center for Dynamical Biomarkers and Translational Medicine, National Central University, Taiwan, which is sponsored by Ministry of Science and Technology (Grant no. MOST103-2911-I-008-001). Also, it was supported by National Chung-Shan Institute of Science & Technology in Taiwan (Grant nos. CSIST-095-V301 and CSIST-095-V302) and National Natural Science Foundation of China (Grant no. 51475342)

Tactile spatial attention enhances gamma-band activity in somatosensory cortex and reduces low-frequency activity in parieto-occipital areas.

We investigated the effects of spatial-selective attention on oscillatory neuronal dynamics in a tactile delayed-match-to-sample task. Whole-head magnetoencephalography was recorded in healthy subjects while dot patterns were presented to their index fingers using Braille stimulators. The subjects’ task was to report the reoccurrence of an initially presented sample pattern in a series of up to eight test stimuli that were presented unpredictably to their right or left index finger. Attention was cued to one side (finger) at the beginning of each trial, and subjects performed the task at the attended side, ignoring the unattended side. After stimulation, high-frequency gamma-band activity (60 –95 Hz) in presumed primary somatosensory cortex (S1) was enhanced, whereas alpha- and beta-band activity were suppressed in somatosensory and occipital areas and then rebounded. Interestingly, despite the absence of any visual stimulation, we also found time-locked activation of medial occipital, presumably visual, cortex. Most relevant, spatial tactile attention enhanced stimulus-induced gamma-band activity in brain regions consistent with contralateral S1 and deepened and prolonged the stimulus induced suppression of beta- and alpha-band activity, maximal in parieto-occipital cortex. Additionally, the beta rebound over contralateral sensorimotor areas was suppressed. Wehypothesize that spatial-selective attention enhances the saliency of sensory representations by synchronizing neuronal responses in early somatosensory cortex and thereby enhancing their impact on downstream areas and facilitating interareal processing. Furthermore, processing of tactile patterns also seems to recruit visual cortex and this even more so for attended compared with unattended stimuli

Heterogeneous data fusion for brain psychology applications

This thesis aims to apply Empirical Mode Decomposition (EMD), Multiscale Entropy (MSE), and collaborative adaptive filters for the monitoring of different brain consciousness states. Both block based and online approaches are investigated, and a possible extension to the monitoring and identification of Electromyograph (EMG) states is provided. Firstly, EMD is employed as a multiscale time-frequency data driven tool to decompose a signal into a number of band-limited oscillatory components; its data driven nature makes EMD an ideal candidate for the analysis of nonlinear and non-stationary data. This methodology is further extended to process multichannel real world data, by making use of recent theoretical advances in complex and multivariate EMD. It is shown that this can be used to robustly measure higher order features in multichannel recordings to robustly indicate ‘QBD’. In the next stage, analysis is performed in an information theory setting on multiple scales in time, using MSE. This enables an insight into the complexity of real world recordings. The results of the MSE analysis and the corresponding statistical analysis show a clear difference in MSE between the patients in different brain consciousness states. Finally, an online method for the assessment of the underlying signal nature is studied. This method is based on a collaborative adaptive filtering approach, and is shown to be able to approximately quantify the degree of signal nonlinearity, sparsity, and non-circularity relative to the constituent subfilters. To further illustrate the usefulness of the proposed data driven multiscale signal processing methodology, the final case study considers a human-robot interface based on a multichannel EMG analysis. A preliminary analysis shows that the same methodology as that applied to the analysis of brain cognitive states gives robust and accurate results. The analysis, simulations, and the scope of applications presented suggest great potential of the proposed multiscale data processing framework for feature extraction in multichannel data analysis. Directions for future work include further development of real-time feature map approaches and their use across brain-computer and brain-machine interface applications

Filtering and thresholding the analytic signal envelope in order to improve peak and spike noise reduction in EEG signals

To remove peak and spike artifacts in biological time series has represented a hard challenge in the last decades. Several methods have been implemented mainly based on adaptive filtering in order to solve this problem. This work presents an algorithm for removing peak and spike artifacts based on a threshold built on the analytic signal envelope. The algorithm was tested on simulated and real EEG signals that contain peak and spike artifacts with random amplitude and frequency occurrence. The performance of the filter was compared with commonly used adaptive filters. Three indexes were used for testing the performance of the filters: Correlation coefficient, mean of coherence function, and rate of absolute error. All these indexes were calculated between filtered signal and original signal without noise. It was found that the new proposed filter was able to reduce the amplitude of peak and spike artifacts with > 0.85, C > 0.8, and RAE 1)