Analytical characterisation of the terahertz in-vivo nano-network in the presence of interference based on TS-OOK communication scheme

The envisioned dense nano-network inside the human body at terahertz (THz) frequency suffers a communication performance degradation among nano-devices. The reason for this performance limitation is not only the path loss and molecular absorption noise, but also the presence of multi-user interference and the interference caused by utilising any communication scheme, such as time spread ON—OFF keying (TS-OOK). In this paper, an interference model utilising TS-OOK as a communication scheme of the THz communication channel inside the human body has been developed and the probability distribution of signal-to-interference-plus-noise ratio (SINR) for THz communication within different human tissues, such as blood, skin, and fat, has been analyzed and presented. In addition, this paper evaluates the performance degradation by investigating the mean values of SINR under different node densities in the area and the probabilities of transmitting pulses. It results in the conclusion that the interference restrains the achievable communication distance to approximate 1 mm, and more specific range depends on the particular transmission circumstance. Results presented in this paper also show that by controlling the pulse transmission probability and node density, the system performance can be ameliorated. In particular, SINR of in vivo THz communication between the deterministic targeted transmitter and the receiver with random interfering nodes in the medium improves about 10 dB, when the node density decreases one order. The SINR increases approximate 5 and 2 dB, when the pulse transmitting probability drops from 0.5 to 0.1 and 0.9 to 0.5

Analytical modelling of the effect of noise on the terahertz in-vivo communication channel for body-centric nano-networks

The paper presents an analytical model of the terahertz (THz) communication channel (0.1 - 10 THz) for in-vivo nano-networks by considering the effect of noise on link quality and information rate. The molecular absorption noise model for in-vivo nano-networks is developed based on the physical mechanisms of the noise present in the medium, which takes into account both the radiation of the medium and the molecular absorption from the transmitted signal. The signal-to-noise ratio (SNR) of the communication channel is investigated for different power allocation schemes and the maximum achievable information rate is studied to explore the potential of THz communication inside the human body. The obtained results show that the information rate is inversely proportional to the transmission distance. Based on the studies on channel performance, it can be concluded that the achievable transmission distance of in-vivo THz nano-networks should be restrained to approximately 2 mm maximum, while the operation band of in-vivo THz nano-networks should be limited to the lower band of the THz band. This motivates the utilisation of hierarchical/cooperative networking concepts and hybrid communication techniques using molecular and electromagnetic methods for future body-centric nano-networks

Mathematical modeling of ultra wideband in vivo radio channel

This paper proposes a novel mathematical model for an in vivo radio channel at ultra-wideband frequencies (3.1–10.6 GHz), which can be used as a reference model for in vivo channel response without performing intensive experiments or simulations. The statistics of error prediction between experimental and proposed model is RMSE = 5.29, which show the high accuracy of the proposed model. Also, the proposed model was applied to the blind data, and the statistics of error prediction is RMSE = 7.76, which also shows a reasonable accuracy of the model. This model will save the time and cost on simulations and experiments, and will help in designing an accurate link budget calculation for a future enhanced system for ultra-wideband body-centric wireless systems

Modulation mode detection and classification for in-vivo nano-scale communication systems operating in terahertz band

This paper initiates the efforts to design an intelligent/cognitive nano receiver operating in terahertz band. Specifically, we investigate two essential ingredients of an intelligent nano receiver—modulation mode detection (to differentiate between pulse-based modulation and carrier-based modulation) and modulation classification (to identify the exact modulation scheme in use). To implement modulation mode detection, we construct a binary hypothesis test in nano-receiver’s passband and provide closed-form expressions for the two error probabilities. As for modulation classification, we aim to represent the received signal of interest by a Gaussian mixture model (GMM). This necessitates the explicit estimation of the THz channel impulse response and its subsequent compensation (via deconvolution). We then learn the GMM parameters via expectation–maximization algorithm. We then do Gaussian approximation of each mixture density to compute symmetric Kullback–Leibler divergence in order to differentiate between various modulation schemes (i.e., ${M}$ -ary phase shift keying and ${M}$ -ary quadrature amplitude modulation). The simulation results on mode detection indicate that there exists a unique Pareto-optimal point (for both SNR and the decision threshold), where both error probabilities are minimized. The main takeaway message by the simulation results on modulation classification is that for a pre-specified probability of correct classification, higher SNR is required to correctly identify a higher order modulation scheme. On a broader note, this paper should trigger the interest of the community in the design of intelligent/cognitive nano receivers (capable of performing various intelligent tasks, e.g., modulation prediction, and so on)

A comprehensive survey on hybrid communication in context of molecular communication and terahertz communication for body-centric nanonetworks

With the huge advancement of nanotechnology over the past years, the devices are shrinking into micro-scale, even nano-scale. Additionally, the Internet of nano-things (IoNTs) are generally regarded as the ultimate formation of the current sensor networks and the development of nanonetworks would be of great help to its fulfilment, which would be ubiquitous with numerous applications in all domains of life. However, the communication between the devices in such nanonetworks is still an open problem. Body-centric nanonetworks are believed to play an essential role in the practical application of IoNTs. BCNNs are also considered as domain specific like wireless sensor networks and always deployed on purpose to support a particular application. In these networks, electromagnetic and molecular communications are widely considered as two main promising paradigms and both follow their own development process. In this survey, the recent developments of these two paradigms are first illustrated in the aspects of applications, network structures, modulation techniques, coding techniques and security to then investigate the potential of hybrid communication paradigms. Meanwhile, the enabling technologies have been presented to apprehend the state-of-art with the discussion on the possibility of the hybrid technologies. Additionally, the inter-connectivity of electromagnetic and molecular body-centric nanonetworks is discussed. Afterwards, the related security issues of the proposed networks are discussed. Finally, the challenges and open research directions are presented

Impact of Fibroblast Cell Density on the Material Parameters of Thin Artificial Human Skin in the Terahertz Band

This paper presents the material parameters of collagen gel and dermal equivalents with different fibroblast cell densities in a Terahertz (THz) band from 0.2 THz to 1.5 THz. It is shown that collagen gel without cells has much higher refractive index and absorption coefficient than dermal equivalents, while the parameters of dermal equivalents slightly decrease with cell density. It denotes that the material parameters at the THz band is not only dependent on the water concentration but also their intrinsic biological features. The obtained results help understand the interaction of the THz wave with biological tissues and the diversity of material parameters of real human skin

Characterisation of the In-vivo Terahertz Communication Channel within the Human Body Tissues for Future Nano-Communication Networks.

PhDBody centric communication has been extensively studied in the past for a range of frequencies, however the need to reduce the size of the devices makes nano-scale technologies attractive for future applications. This opens up opportunities of applying nano-devices made of the novel materials, like carbon nano tubes (CNT), graphene and etc., which operate at THz frequencies and probably inside human bodies. With a brief introduction of nano-communications and review of the state of the art, three main contributions have been demonstrated in this thesis to characterise nano-scale body-centric communication at THz band: • A novel channel model has been studied. The path loss values obtained from the simulation have been compared with an analytical model in order to verify the feasibility of the numerical analysis. On the basis of the path loss model and noise model, the channel capacity is also investigated. • A 3-D stratified skin model is built to investigate the wave propagation from the under-skin to skin surface and the influence of the rough interface between different skin layers is investigated by introducing two detailed skin models with different interfaces (i.e.,3-D sine function and 3-D sinc function). In addition, the effects of the inclusion of the sweat duct is also analysed and the results show great potential of the THz waves on sensing and communicating. • Since the data of dielectric properties for biological materials at THz band are quite scarce, in collaboration with the Blizard Institute, London, UK, different human tissues such as skin, blood, muscle and etc. are planned to be measured with the THz Time Domain Spectroscopy (THz-TDS) system at Queen Mary University of London to enrich the database of electromagnetic parameters at the band of interest. In this chapter, collagen, the main constitution of skin was i mainly studied. Meanwhile, the measured results are compared with the simulated ones with a good agreement. Finally, a plan for further research activities is presented, aiming at widening and deepening the present understanding of the THz body-centric nano-communication channel, thus providing a complete characterisation useful for the design of reliable and efficient body centric nano-networks. iiChina Scholarship Council Queen Mary University of Londo

Efficient Communication Protocols for Wireless Nanoscale Sensor Networks

Advances in nanotechnology are paving the way for wireless nanoscale sensor networks (WNSNs), promising radically new applications in medical, biological, and chemical fields. However, the small scale poses formidable challenges for communication. First, small nanomaterial-based antennas communicate in the terahertz band, which coincides with the natural resonance frequencies of many types of molecules causing severe molecular absorption and noise. The problem is particularly complicated if the molecular composition of the channel changes over time, causing time-varying absorption and noise. Second, as it is not practical to fit large batteries or replace batteries in a small device, these devices are expected to power themselves by harvesting ambient energy from the environment. However, the amount of energy that can be harvested is directly proportional to the size of the harvester. A nanodevice therefore can generate only a tiny fraction of its total power consumption, which requires us to rethink the design of communication protocols for self-powering WNSNs. In order to address aforementioned challenges, this thesis makes three fundamental contributions. First, it proposes dynamic frequency and power selection as a means to overcome the first problem, i.e, changing molecular composition problem in a time-varying terahertz channel. The dynamic frequency/power selection problem is modelled as a Markov Decision Process to derive the optimal solutions, while several practical heuristics are proposed that achieve close to optimal solutions. Second, to address the severe power shortage problem in a self-powering nanodevice, this thesis proposes a mechanism to exploit the information contained in the energy harvesting data to detect the energy-dissipating events occurring in the environment. This form of event monitoring makes dual use of the energy-harvesting unit in the nanodevice, i.e., it is used to generate power as well as monitor the environment, thus saving significant energy, which otherwise would have been used to power the onboard sensors. Finally, novel WNSN applications are designed and analysed to monitor and control chemical reactors at the molecular level with the ultimate goal of increasing the selectivity of the reactor. It is shown that using the proposed communication protocols for a time-varying terahertz channel, the selectivity of the reactor can be significantly increased, beyond what can be achieved with conventional solutions

Security Applications for Converging Technologies - Impact on the Constitutional State and the Legal order

In this study we investigate the impact of converging technologies on legal practice and criminology in a forward looking study intended for practitioners and policy makers in the field of legislation, crime prevention, and law enforcement. We look at a 15 years timeframe and discuss the scientific and technical progress in various domains as well as the ethical, legal, and policy dilemmas involved.