Antenna design for microwave hepatic ablation using an axisymmetric electromagnetic model

BACKGROUND: An axisymmetric finite element method (FEM) model was employed to demonstrate important techniques used in the design of antennas for hepatic microwave ablation (MWA). To effectively treat deep-seated hepatic tumors, these antennas should produce a highly localized specific absorption rate (SAR) pattern and be efficient radiators at approved generator frequencies. METHODS AND RESULTS: As an example, a double slot choked antenna for hepatic MWA was designed and implemented using FEMLAB™ 3.0. DISCUSSION: This paper emphasizes the importance of factors that can affect simulation accuracy, which include boundary conditions, the dielectric properties of liver tissue, and mesh resolution

Antenna and system design for controlled delivery of microwave thermal ablation

Doctor of PhilosophyDepartment of Electrical and Computer EngineeringPunit PrakashMicrowave ablation is an established minimally invasive modality for thermal ablation of unresectable tumors and other diseases. The goal of a microwave ablation procedure is to deliver microwave power in a manner localized to the targeted tissue, with the objective of raising the target tissue to ablative temperatures (~60 °C). Engineering efforts in microwave applicator design have largely been focused on the design of microwave antennas that yield large, near-spherical ablation zones, and can fit within rigid needles or flexible catheters. These efforts have led to significant progress in the development and clinical application of microwave ablation systems, particularly for treating tumors in the liver and other highly vascular organs. However, currently available applicator designs are ill-suited to treating targets of diverse shapes and sizes. Furthermore, there are a lack of non-imaging-based techniques for monitoring the transient progression of the ablation zone as a means for providing feedback to the physician. This dissertation presents the design, implementation, and experimental evaluation of microwave ablation antennas for site-specific therapeutic applications with these issues in mind. A deployable 915 MHz loop antenna is presented, providing a minimally-invasive approach for thermal ablation of the endometrial lining of the uterus for treatment of heavy menstrual bleeding. The antenna incorporates a radiating loop, which can be deployed to adjustable shapes within the uterine cavity, and a passive element, to enable thermal ablation, to 5.7–9.6 mm depth, of uterine cavities ranging in size from 4–6.5 cm in length and 2.5–4.5 cm in width. Electromagnetic–bioheat transfer simulations were employed for design optimization of the antennas, and proof-of-concept applicators were fabricated and extensively evaluated in ex vivo tissue. Finally, feasibility of using the broadband antenna reflection coefficient for monitoring the ablation progress during the course of ablation was evaluated. Experimental studies demonstrated a shift in antenna resonant frequency of 50 MHz correlated with complete ablation. For treatment of 1–2 cm spherical targets, water-cooled monopole antennas operating at 2.45 and 5.8 GHz were designed and experimentally evaluated in ex vivo tissue. The technical feasibility of using these applicators for treating 1–2 cm diameter benign adrenal adenomas was demonstrated. These studies demonstrated the potential of using minimally-invasive microwave ablation applicators for treatment of hypertension caused by benign aldosterone producing adenomas. Since tissue dielectric properties have been observed to change substantially at elevated temperatures, knowledge of the temperature-dependence of tissue dielectric properties may provide a means for estimating treatment state from changes in antenna reflection coefficient during a procedure. The broadband dielectric properties of bovine liver, an established tissue for experimental characterization of microwave ablation applicators, were measured from room temperature to ablative temperatures. The measured dielectric data were fit to a parametric model using piecewise linear functions, providing a means for readily incorporating these data into computational models. These data represent the first report of changes in broadband dielectric properties of liver tissue at ablative temperatures and should help enable additional studies in ablation system development

Electromagnetism of Microwave Heating

Detailed electrodynamic descriptions of the fundamental workings of microwave heating devices are presented. We stress that all results come from Maxwell equations and the boundary conditions (BC). We analyze one by one the principal components of a microwave heater; the cooking chamber, the waveguide, and the microwave sources, either klystron or magnetron. The boundary conditions at the walls of the resonant cavity and at the interface air/surface of the food are given and show how relevant the BC are to understand how the microwaves penetrate the nonconducting, electric polarizable specimen. We mention the application of microwaving waste plastics to obtain a good H2 quantity that could be used as a clean energy source for other machines. We obtained trapped stationary microwaves in the resonant cavity and traveling waves in the waveguides. We show 3D plots of the mathematical solutions and agree quite well with experimental measurements of hot/cold patterns. Simulations for cylindrical cavities are shown. The radiation processes in klystrons and magnetrons are described with some detail in terms of the accelerated electrons and their trajectories. These fields are sent to the waveguides and feed the cooking chamber. Whence, we understand how a meal or waste plastic, or an industrial sample is microwave heated

Electromagnetic Wave Propagation for Industry and Biomedical Applications

This book highlights original research and high-quality technical briefs on electromagnetic wave propagation, radiation, and scattering, and their applications in industry and biomedical engineering. It also presents recent research achievements in the theoretical, computational, and experimental aspects of electromagnetic wave propagation, radiation, and scattering. The book is divided into three sections. Section 1 consists of chapters with general mathematical methods and approaches to the forward and inverse problems of wave propagation. Section 2 presents the problems of wave propagation in superconducting materials and porous media. Finally, Section 3 discusses various industry and biomedical applications of electromagnetic wave propagation, radiation, and scattering

Analysis of a novel expanded tip wire (ETW) antenna for microwave ablation of cardiac arrhythmias

A novel expanded tip wire (ETW) catheter antenna is proposed for microwave ablation for the treatment of atrial fibrillation (AF). The antenna is designed as an integral part of coaxial cable so that it can be inserted via a 6F catheter. A numerical model based on the rotationally symmetric finite-difference time-domain technique incorporating the generalized perfectly matched layer as the absorbing boundary condition has been utilized to accurately model the interaction between the antenna and the myocardium. Numerical and in-vitro experimental results are presented for specific absorption rate, return loss and heating pattern produced by the antenna. Both numerical modeling and in-vitro experimentation show that the proposed ETW antenna produces a well-defined electric field distribution that provides continuous long and linear lesions for the treatment of AF. © 2003 IEEE