A multi-view approach to cDNA micro-array analysis

The official published version can be obtained from the link below.Microarray has emerged as a powerful technology that enables biologists to study thousands of genes simultaneously, therefore, to obtain a better understanding of the gene interaction and regulation mechanisms. This paper is concerned with improving the processes involved in the analysis of microarray image data. The main focus is to clarify an image's feature space in an unsupervised manner. In this paper, the Image Transformation Engine (ITE), combined with different filters, is investigated. The proposed methods are applied to a set of real-world cDNA images. The MatCNN toolbox is used during the segmentation process. Quantitative comparisons between different filters are carried out. It is shown that the CLD filter is the best one to be applied with the ITE.This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC) of the UK under Grant GR/S27658/01, the National Science Foundation of China under Innovative Grant 70621001, Chinese Academy of Sciences under Innovative Group Overseas Partnership Grant, the BHP Billiton Cooperation of Australia Grant, the International Science and Technology Cooperation Project of China under Grant 2009DFA32050 and the Alexander von Humboldt Foundation of Germany

Kajian motivasi ekstrinsik di antara Pelajar Lepasan Sijil dan Diploma Politeknik Jabatan Kejuruteraan Awam KUiTTHO

Kajian ini dijalankan untuk menyelidiki pengaruh dorongan keluarga, cara pengajaran pensyarah, pengaruh rakan sebaya dan kemudahan infrastruktur terhadap motivasi ekstrinsik bagi pelajar tahun tiga dan tahun empat lepasan sijil dan diploma politeknik Jabatan Kejuruteraan Awain Kolej Universiti Teknologi Tun Hussein Onn. Sampel kajian ini beijumlah 87 orang bagi pelajar lepasan sijil politeknik dan 38 orang bagi lepasan diploma politeknik. Data kajian telah diperolehi melalui borang soal selidik dan telah dianalisis menggunakan perisian SPSS (Statical Package For Sciences). Hasil kajian telah dipersembahkan dalam bentuk jadual dan histohgrapi. Analisis kajian mendapati bahawa kedua-dua kumpulan setuju bahawa faktor-faktor di atas memberi kesan kepada motivasi ekstrinsik mereka. Dengan kata lain faktpr-faktor tersebut penting dalam membentuk pelajar mencapai kecemerlangan akademik

Adaptive Nonlocal Filtering: A Fast Alternative to Anisotropic Diffusion for Image Enhancement

The goal of many early visual filtering processes is to remove noise while at the same time sharpening contrast. An historical succession of approaches to this problem, starting with the use of simple derivative and smoothing operators, and the subsequent realization of the relationship between scale-space and the isotropic dfffusion equation, has recently resulted in the development of "geometry-driven" dfffusion. Nonlinear and anisotropic diffusion methods, as well as image-driven nonlinear filtering, have provided improved performance relative to the older isotropic and linear diffusion techniques. These techniques, which either explicitly or implicitly make use of kernels whose shape and center are functions of local image structure are too computationally expensive for use in real-time vision applications. In this paper, we show that results which are largely equivalent to those obtained from geometry-driven diffusion can be achieved by a process which is conceptually separated info two very different functions. The first involves the construction of a vector~field of "offsets", defined on a subset of the original image, at which to apply a filter. The offsets are used to displace filters away from boundaries to prevent edge blurring and destruction. The second is the (straightforward) application of the filter itself. The former function is a kind generalized image skeletonization; the latter is conventional image filtering. This formulation leads to results which are qualitatively similar to contemporary nonlinear diffusion methods, but at computation times that are roughly two orders of magnitude faster; allowing applications of this technique to real-time imaging. An additional advantage of this formulation is that it allows existing filter hardware and software implementations to be applied with no modification, since the offset step reduces to an image pixel permutation, or look-up table operation, after application of the filter

Cellular neural networks, Navier-Stokes equation and microarray image reconstruction

Copyright @ 2011 IEEE.Although the last decade has witnessed a great deal of improvements achieved for the microarray technology, many major developments in all the main stages of this technology, including image processing, are still needed. Some hardware implementations of microarray image processing have been proposed in the literature and proved to be promising alternatives to the currently available software systems. However, the main drawback of those proposed approaches is the unsuitable addressing of the quantification of the gene spot in a realistic way without any assumption about the image surface. Our aim in this paper is to present a new image-reconstruction algorithm using the cellular neural network that solves the Navier–Stokes equation. This algorithm offers a robust method for estimating the background signal within the gene-spot region. The MATCNN toolbox for Matlab is used to test the proposed method. Quantitative comparisons are carried out, i.e., in terms of objective criteria, between our approach and some other available methods. It is shown that the proposed algorithm gives highly accurate and realistic measurements in a fully automated manner within a remarkably efficient time