A comprehensive study on disease risk predictions in machine learning

Over recent years, multiple disease risk prediction models have been developed. These models use various patient characteristics to estimate the probability of outcomes over a certain period of time and hold the potential to improve decision making and individualize care. Discovering hidden patterns and interactions from medical databases with growing evaluation of the disease prediction model has become crucial. It needs many trials in traditional clinical findings that could complicate disease prediction. Comprehensive survey on different strategies used to predict disease is conferred in this paper. Applying these techniques to healthcare data, has improvement of risk prediction models to find out the patients who would get benefit from disease management programs to reduce hospital readmission and healthcare cost, but the results of these endeavours have been shifted

Information Systems and Healthcare XXXIV: Clinical Knowledge Management Systems—Literature Review and Research Issues for Information Systems

Knowledge Management (KM) has emerged as a possible solution to many of the challenges facing U.S. and international healthcare systems. These challenges include concerns regarding the safety and quality of patient care, critical inefficiency, disparate technologies and information standards, rapidly rising costs and clinical information overload. In this paper, we focus on clinical knowledge management systems (CKMS) research. The objectives of the paper are to evaluate the current state of knowledge management systems diffusion in the clinical setting, assess the present status and focus of CKMS research efforts, and identify research gaps and opportunities for future work across the medical informatics and information systems disciplines. The study analyzes the literature along two dimensions: (1) the knowledge management processes of creation, capture, transfer, and application, and (2) the clinical processes of diagnosis, treatment, monitoring and prognosis. The study reveals that the vast majority of CKMS research has been conducted by the medical and health informatics communities. Information systems (IS) researchers have played a limited role in past CKMS research. Overall, the results indicate that there is considerable potential for IS researchers to contribute their expertise to the improvement of clinical process through technology-based KM approaches

A Classification System for Diabetic Patients with Machine Learning Techniques

International audienceDiabetes mellitus (DM) is a group of metallic disorder characterized by steep levels of blood glucose prolonged over a time. It results the defection in insulin production or improper action of the cells to the insulin produced. It is one of the significant public health care challenge worldwide. Diabetes exists in a body when pancreas does not construct enough hormone insulin or the human body is not being able to use the insulin properly. The diagnosis of diabetes (diagnosis, etiopathophysiology, therapy etc.) need to generate and process the vast amount of data. Data mining techniques have proven its usefulness and effectiveness in order to evaluate the unknown relationships or patterns if exists with such vast data. In the present work, five techniques based on machine learning namely, AdaBoost, LogicBoost, RobustBoost, Naïve Bayes and Bagging have been proposed for the analysis and prediction of DM patients. The proposed techniques are employed on the data set of Pima Indians Diabetes patients. The results computed are found to be very accurate with classification accuracy of 81.77% and 79.69% by bagging and AdaBoost techniques, respectively. Hence, the proposed techniques employed here are highly adorable, effective and efficient in order to predict the DM

Mining of nutritional ingredients in food for disease analysis

Suitable nutritional diets have been widely recognized as important measures to prevent and control non-communicable diseases (NCDs). However, there is little research on nutritional ingredients in food now, which are beneficial to the rehabilitation of NCDs. In this paper, we profoundly analyzed the relationship between nutritional ingredients and diseases by using data mining methods. First, more than 7,000 diseases were obtained and we collected the recommended food and taboo food for each disease. Then, referring to the China Food Nutrition, we used noise-intensity and information entropy to find out which nutritional ingredients can exert positive effects on diseases. Finally, we proposed an improved algorithm named CVNDA_Red based on rough sets to select the corresponding core ingredients from the positive nutritional ingredients. To the best of our knowledge, this is the first study to discuss the relationship between nutritional ingredients in food and diseases through data mining based on rough set theory in China. The experiments on real-life data show that our method based on data mining improves the performance compared with the traditional statistical approach, with the precision of 1.682. Additionally, for some common diseases such as Diabetes, Hypertension and Heart disease, our work is able to identify correctly the first two or three nutritional ingredients in food that can benefit the rehabilitation of those diseases. These experimental results demonstrate the effectiveness of applying data mining in selecting of nutritional ingredients in food for disease analysis

Iterative annotation to ease neural network training: Specialized machine learning in medical image analysis

Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in the field of pathology, we have created an intuitive interface which utilizes the commonly used whole slide image (WSI) viewer, Aperio ImageScope (Leica Biosystems Imaging, Inc.), for the annotation and display of neural network predictions on WSIs. Leveraging this, we propose the use of a human-in-the-loop strategy to reduce the burden of WSI annotation. We track network performance improvements as a function of iteration and quantify the use of this pipeline for the segmentation of renal histologic findings on WSIs. More specifically, we present network performance when applied to segmentation of renal micro compartments, and demonstrate multi-class segmentation in human and mouse renal tissue slides. Finally, to show the adaptability of this technique to other medical imaging fields, we demonstrate its ability to iteratively segment human prostate glands from radiology imaging data.Comment: 15 pages, 7 figures, 2 supplemental figures (on the last page

A Web-Based Medical Diagnostic System using Data Mining Technique

The purpose of this paper is to apply data mining technique for medical diagnostic system on web application supporting Thai language. This web would help users to reduce expense and time of visiting doctors. It is capable of giving preliminary diagnosis. The proposed system will discover the implication knowledge with association rules derived from formal concept analysis (FCA) to advice co-symptom of diagnosing to achieve more correctly. The association rules are built from its subconcept and superconcept relation from concept lattice. In addition, the proposed system supporting Thai language is challenged because this language is streaming string without the boundary delimiters. The proposed system is developed based on online web application to demonstrate real situation. The result show that the proposed system can suggest co-symptom to achieve more correctness for medical diagnosti

Recent Developments in Smart Healthcare

Medicine is undergoing a sector-wide transformation thanks to the advances in computing and networking technologies. Healthcare is changing from reactive and hospital-centered to preventive and personalized, from disease focused to well-being centered. In essence, the healthcare systems, as well as fundamental medicine research, are becoming smarter. We anticipate significant improvements in areas ranging from molecular genomics and proteomics to decision support for healthcare professionals through big data analytics, to support behavior changes through technology-enabled self-management, and social and motivational support. Furthermore, with smart technologies, healthcare delivery could also be made more efficient, higher quality, and lower cost. In this special issue, we received a total 45 submissions and accepted 19 outstanding papers that roughly span across several interesting topics on smart healthcare, including public health, health information technology (Health IT), and smart medicine