Hybrid inorganic/organic photonic crystal biochips for cancer biomarkers detection

We report on hybrid inorganic/organic one-dimensional photonic crystal biochips sustaining Bloch surface waves. The biochips were used, together with an optical platform operating in a label-free and fluorescence configuration simultaneously, to detect the cancer biomarker Angiopoietin 2 in a protein base buffer. The hybrid photonic crystals embed in their geometry a thin functionalization poly-acrylic acid layer deposited by plasma polymerization, which is used to immobilize a monoclonal antibody for highly specific biological recognition. The fluorescence operation mode is described in detail, putting into evidence the role of field enhancement and localization at the photonic crystal surface in the shaping and intensification of the angular fluorescence pattern. In the fluorescence operation mode, the hybrid biochips can attain the limit of detection 6 ng/ml.We report on hybrid inorganic/organic one-dimensional photonic crystal biochips sustaining Bloch surface waves. The biochips were used, together with an optical platform operating in a label-free and fluorescence configuration simultaneously, to detect the cancer biomarker Angiopoietin 2 in a protein base buffer. The hybrid photonic crystals embed in their geometry a thin functionalization poly-acrylic acid layer deposited by plasma polymerization, which is used to immobilize a monoclonal antibody for highly specific biological recognition. The fluorescence operation mode is described in detail, putting into evidence the role of field enhancement and localization at the photonic crystal surface in the shaping and intensification of the angular fluorescence pattern. In the fluorescence operation mode, the hybrid biochips can attain the limit of detection 6 ng/ml

A hybrid Brayton engine concept

A first generation open cycle Brayton engine concept for use in full scale solar module testing was defined. The concept extended to include solar/fossil hybrid capability. The combustion system defined for hybrid operation consists of a wide range combustor liner, a single airblast atomizer, an ignitor and a high-voltage ignition unit. Wide range combustor operation would be achieved through combining pilot and primary zones. The hybrid control mode and the solar only control mode are both based on the concept of maintaining constant turbine inlet temperature and varying the engine speed for part-power operation. In addition, the hybrid control concept will allow the operator to set a minimum thermal power input to the engine by setting a corresponding minimum engine speed. When the solar thermal power input falls below this minimum, fossil fuel would be utilized to augment the solar thermal power input

An Hybrid Mode of Operation

In this paper I propose a tweakable block cipher construction with a mode of operation that combines counter and chaining methods. Using a single key, the direct application of this mode produces unrepeatable message authentication tags

Parameter estimation for stochastic hybrid model applied to urban traffic flow estimation

This study proposes a novel data-based approach for estimating the parameters of a stochastic hybrid model describing the traffic flow in an urban traffic network with signalized intersections. The model represents the evolution of the traffic flow rate, measuring the number of vehicles passing a given location per time unit. This traffic flow rate is described using a mode-dependent first-order autoregressive (AR) stochastic process. The parameters of the AR process take different values depending on the mode of traffic operation – free flowing, congested or faulty – making this a hybrid stochastic process. Mode switching occurs according to a first-order Markov chain. This study proposes an expectation-maximization (EM) technique for estimating the transition matrix of this Markovian mode process and the parameters of the AR models for each mode. The technique is applied to actual traffic flow data from the city of Jakarta, Indonesia. The model thus obtained is validated by using the smoothed inference algorithms and an online particle filter. The authors also develop an EM parameter estimation that, in combination with a time-window shift technique, can be useful and practical for periodically updating the parameters of hybrid model leading to an adaptive traffic flow state estimator

A low cost air hybrid concept

This article is a pre-print version of the full and final article which is available at the link below.Copyright © 2010 Institut français du pétrole Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than IFP must be honored. Abstracting with credit is permitted. To copy otherwise, to republish, to post on servers, or to redistribute to lists, requires prior specific permission and/or a fee: Request permission from Documentation, Institut français du pétrole, fax. +33 1 47 52 70 78, or [email protected] air hybrid engine absorbs the vehicle kinetic energy during braking, stores it in an air tank in the form of compressed air, and reuses it to propel a vehicle during cruising and acceleration. Capturing, storing and reusing this braking energy to give additional power can therefore improve fuel economy, particularly in cities and urban areas where the traffic conditions involve many stops and starts. In order to reuse the residual kinetic energy, the vehicle operation consists of 3 basic modes, i.e. Compression Mode (CM), Expander Mode (EM) and normal firing mode. Unlike previous works, a low cost air hybrid engine has been proposed and studied. The hybrid engine operation can be realised by means of production technologies, such as VVT and valve deactivation. In this work, systematic investigation has been carried out on the performance of the hybrid engine concept through detailed gas dynamic modelling using Ricardo WAVE software. Valve timing optimization has been done for the more efficient operation of air hybrid operation and obtaining higher braking and Motoring mean effective pressure for CM and EM respectively.EPSR

Evaluation of a series hybrid thrust bearing at DN values to three million. 2: Fabrication and testing

Results of tests made to determine the experimental performance of a series hybrid bearing are reported. The bearing consists of a 150 mm ball bearing and a centrifugally actuated, conical, fluid film bearing fitting an envelope with an outer radius of 86.4 mm (3.4 in.) and inner radius of 71 mm (2.8 in.). Tests were conducted up to 16,500 rpm, at which speed an axial load of 15,568 N (3500 lb) was safely supported by the hybrid bearing system. Through the employment of the series hybrid bearing principle, it was possible to reduce the effective ball bearing speed to approximately one-half of the shaft speed. A reduction of this magnitude should result in a tenfold increase in the ball bearing fatigue life. A successful simulation of fluid film bearing lubricant supply failure, performed repeatedly at an operating speed of 10,000 rpm, resulted in complete and smooth change over to full scale ball bearing operation when the oil supply to the fluid film bearing was discontinued. Reactivation of the fluid film supply system produced a flawless return to the original mode of hybrid operation

Design and evaluation of a 3 million DN series-hybrid thrust bearing

The bearing, consisting of a 150-mm ball bearing and a centrifugally actuated, conical, fluid-film bearing, was fatigue tested. Test conditions were representative of a mainshaft ball bearing in a gas turbine engine operating at maximum thrust load to simulate aircraft takeoff conditions. Tests were conducted up to 16000 rpm and at this speed an axial load of 15568 newtons (3500 lb) was safely supported by the hybrid bearing system. Through the series-hybrid bearing principle, the effective ball bearing speed was reduced to approximately one-half of the shaft speed. It was concluded that a speed reduction of this magnitude results in a ten-fold increase in the ball bearing fatigue life. A successful evaluation of fluid-film bearing lubricant supply failure was performed repeatedly at an operating speed of 10,000 rpm. A complete and smooth changeover to full-scale ball bearing operation was effected when the oil supply to the fluid-film bearing was cut off. Reactivation of the fluid-film oil supply system resulted in a flawless return to the original mode of hybrid operation

Coordinated Control of Diesel Generators and Batteries in DC Hybrid Electric Shipboard Power System

Hybrid electric ships powered by diesel generators and batteries are the main configuration for shipboard microgrids (SMGs) in the current maritime industry. Extensive studies have been conducted for the hybrid operation mode, whereas the all-electric operation mode and the switching between the aforementioned two modes in a system with multiple generators and batteries have not been tested. In this paper, a coordinated approach for a hybrid electric ship is proposed, where two operation modes have been simultaneously considered. More specifically, for achieving an efficient operation with reduced generator wear losses, the governor-less diesel-engine-driven generators have been adopted in the study. According to the practical operation conditions, two operation modes, the all-electric and hybrid modes, are preset. Based on these, the coordination of the generators acting as the main power sources and batteries regulating the power flow and improving the generator efficiency is studied. The governor-less diesel generators are regulated to inject the rated power in order to maximize the generator efficiency, while the DC bus voltage is regulated by DC/DC converters. For the benefit of the overall lifespan of battery banks, power sharing during charging and discharging states have been realized by the state of charge (SoC)-based adaptive droop regulator. For the test of two operation modes, as well as the mode switching, a simulation assessment in a 1 kV DC SMG has been conducted. The simulation results show that the DC bus voltage can be controlled well, and that the power sharing among batteries follows the design. Additionally, smooth transients can be observed during mode switching when the proposed control scheme is applied