On Algebraic Approach for MSD Parametric Estimation

This article address the identification problem of the natural frequency and the damping ratio of a second order continuous system where the input is a sinusoidal signal. An algebra based approach for identifying parameters of a Mass Spring Damper (MSD) system is proposed and compared to the Kalman-Bucy filter. The proposed estimator uses the algebraic parametric method in the frequency domain yielding exact formula, when placed in the time domain to identify the unknown parameters. We focus on finding the optimal sinusoidal exciting trajectory which allow to minimize the variance of the identification algorithms. We show that the variance of the estimators issued from the algebraic identification method introduced by Fliess and Sira-Ramirez is less sensitive to the input frequency than the ones obtained by the classical recursive Kalman-Bucy filter. Unlike conventional estimation approach, where the knowledge of the statistical properties of the noise is required, algebraic method is deterministic and non-asymptotic. We show that we don't need to know the variance of the noise so as to perform these algebraic estimators. Moreover, as they are non-asymptotic, we give numerical results where we show that they can be used directly for online estimations without any special setting.International audienceThis article address the identification problem of the natural frequency and the damping ratio of a second order continuous system where the input is a sinusoidal signal. An algebra based approach for identifying parameters of a Mass Spring Damper (MSD) system is proposed and compared to the Kalman-Bucy filter. The proposed estimator uses the algebraic parametric method in the frequency domain yielding exact formula, when placed in the time domain to identify the unknown parameters. We focus on finding the optimal sinusoidal exciting trajectory which allow to minimize the variance of the identification algorithms. We show that the variance of the estimators issued from the algebraic identification method introduced by Fliess and Sira-Ramirez is less sensitive to the input frequency than the ones obtained by the classical recursive Kalman-Bucy filter. Unlike conventional estimation approach, where the knowledge of the statistical properties of the noise is required, algebraic method is deterministic and non-asymptotic. We show that we don't need to know the variance of the noise so as to perform these algebraic estimators. Moreover, as they are non-asymptotic, we give numerical results where we show that they can be used directly for online estimations without any special setting

Identification of control targets in Boolean molecular network models via computational algebra

Motivation: Many problems in biomedicine and other areas of the life sciences can be characterized as control problems, with the goal of finding strategies to change a disease or otherwise undesirable state of a biological system into another, more desirable, state through an intervention, such as a drug or other therapeutic treatment. The identification of such strategies is typically based on a mathematical model of the process to be altered through targeted control inputs. This paper focuses on processes at the molecular level that determine the state of an individual cell, involving signaling or gene regulation. The mathematical model type considered is that of Boolean networks. The potential control targets can be represented by a set of nodes and edges that can be manipulated to produce a desired effect on the system. Experimentally, node manipulation requires technology to completely repress or fully activate a particular gene product while edge manipulations only require a drug that inactivates the interaction between two gene products. Results: This paper presents a method for the identification of potential intervention targets in Boolean molecular network models using algebraic techniques. The approach exploits an algebraic representation of Boolean networks to encode the control candidates in the network wiring diagram as the solutions of a system of polynomials equations, and then uses computational algebra techniques to find such controllers. The control methods in this paper are validated through the identification of combinatorial interventions in the signaling pathways of previously reported control targets in two well studied systems, a p53-mdm2 network and a blood T cell lymphocyte granular leukemia survival signaling network.Comment: 12 pages, 4 figures, 2 table

An algebraic method for system reduction of stationary Gaussian systems

System identification for a particular approach reduces to system reduction, determining for a system with a high state-space dimension a system of low state-space dimension. For Gaussian systems the problem of system reduction is considered with the divergence rate criterion. The divergence or Kullback-Leibler pseudo-distance corresponds to the expected value of the negative natural logarithm of the likelihood function. System reduction for Gaussian systems is thus a certainty equivalent way of maximum likelihood identification. An algebraic method is proposed for system reduction. The results are a theorem that this problem reduces to an infimization problem for a rational function for which programs are available and a procedure for computing the best approximant w.r.t. the divergence rate criterion. As illustration two examples of system reduction are presented

A single-step identification strategy for the coupled TITO process using fractional calculus

The reliable performance of a complete control system depends on accurate model information being used to represent each subsystem. The identification and modelling of multivariable systems are complex and challenging due to cross-coupling. Such a system may require multiple steps and decentralized testing to obtain full system models effectively. In this paper, a direct identification strategy is proposed for the coupled two-input two-output (TITO) system with measurable input–output signals. A well-known closed-loop relay test is utilized to generate a set of inputs–outputs data from a single run. Based on the collected data, four individual fractional-order transfer functions, two for main paths and two for cross-paths, are estimated from single-run test signals. The orthogonal series-based algebraic approach is adopted, namely the Haar wavelet operational matrix, to handle the fractional derivatives of the signal in a simple manner. A single-step strategy yields faster identification with accurate estimation. The simulation and experimental studies depict the efficiency and applicability of the proposed identification technique. The demonstrated results on the twin rotor multiple-input multiple- output (MIMO) system (TRMS) clearly reveal that the presented idea works well with the highly coupled system even in the presence of measurement noise