Adaptive gray scale mapping to reduce registration noise in difference images

Difference images are used in various image processing applications such as change detection, radar imaging, remote sensing, and biomedical image analysis. The difference image, or difference picture, is found by subtracting one image from another. One practical problem with difference images is that, if the images are not in perfect spatial registration before subtraction, their difference image will contain artifacts caused by incomplete cancellation of the unchanged background objects. These artifacts (registration noise) show up as extraneous light and dark regions on either side of the background objects. Usually, this noise is reduced by either smoothing (blurring), or thresholding the difference image. This paper describes a new method to reduce registration noise using adaptive gray scale mapping. This simple digital filter reduces registration noise as well as, or better than, previous methods, with less degradation of the actual differences between the images.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/26272/1/0000357.pd

Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates

The study of cerebral anatomy in developing neonates is of great importance for the understanding of brain development during the early period of life. This dissertation therefore focuses on three challenges in the modelling of cerebral anatomy in neonates during brain development. The methods that have been developed all use Magnetic Resonance Images (MRI) as source data. To facilitate study of vascular development in the neonatal period, a set of image analysis algorithms are developed to automatically extract and model cerebral vessel trees. The whole process consists of cerebral vessel tracking from automatically placed seed points, vessel tree generation, and vasculature registration and matching. These algorithms have been tested on clinical Time-of- Flight (TOF) MR angiographic datasets. To facilitate study of the neonatal cortex a complete cerebral cortex segmentation and reconstruction pipeline has been developed. Segmentation of the neonatal cortex is not effectively done by existing algorithms designed for the adult brain because the contrast between grey and white matter is reversed. This causes pixels containing tissue mixtures to be incorrectly labelled by conventional methods. The neonatal cortical segmentation method that has been developed is based on a novel expectation-maximization (EM) method with explicit correction for mislabelled partial volume voxels. Based on the resulting cortical segmentation, an implicit surface evolution technique is adopted for the reconstruction of the cortex in neonates. The performance of the method is investigated by performing a detailed landmark study. To facilitate study of cortical development, a cortical surface registration algorithm for aligning the cortical surface is developed. The method first inflates extracted cortical surfaces and then performs a non-rigid surface registration using free-form deformations (FFDs) to remove residual alignment. Validation experiments using data labelled by an expert observer demonstrate that the method can capture local changes and follow the growth of specific sulcus

Medical imaging analysis with artificial neural networks

Given that neural networks have been widely reported in the research community of medical imaging, we provide a focused literature survey on recent neural network developments in computer-aided diagnosis, medical image segmentation and edge detection towards visual content analysis, and medical image registration for its pre-processing and post-processing, with the aims of increasing awareness of how neural networks can be applied to these areas and to provide a foundation for further research and practical development. Representative techniques and algorithms are explained in detail to provide inspiring examples illustrating: (i) how a known neural network with fixed structure and training procedure could be applied to resolve a medical imaging problem; (ii) how medical images could be analysed, processed, and characterised by neural networks; and (iii) how neural networks could be expanded further to resolve problems relevant to medical imaging. In the concluding section, a highlight of comparisons among many neural network applications is included to provide a global view on computational intelligence with neural networks in medical imaging

Digital Color Imaging

This paper surveys current technology and research in the area of digital color imaging. In order to establish the background and lay down terminology, fundamental concepts of color perception and measurement are first presented us-ing vector-space notation and terminology. Present-day color recording and reproduction systems are reviewed along with the common mathematical models used for representing these devices. Algorithms for processing color images for display and communication are surveyed, and a forecast of research trends is attempted. An extensive bibliography is provided

Calibrating a high-resolution wavefront corrector with a static focal-plane camera

We present a method to calibrate a high-resolution wavefront-correcting device with a single, static camera, located in the focal plane; no moving of any component is needed. The method is based on a localized diversity and differential optical transfer functions (dOTF) to compute both the phase and amplitude in the pupil plane located upstream of the last imaging optics. An experiment with a spatial light modulator shows that the calibration is sufficient to robustly operate a focal-plane wavefront sensing algorithm controlling a wavefront corrector with ~40 000 degrees of freedom. We estimate that the locations of identical wavefront corrector elements are determined with a spatial resolution of 0.3% compared to the pupil diameter.Comment: 12 pages, 12 figures, accepted for publication in Applied Optic

An Adaptive Semi-Parametric and Context-Based Approach to Unsupervised Change Detection in Multitemporal Remote-Sensing Images

In this paper, a novel automatic approach to the unsupervised identification of changes in multitemporal remote-sensing images is proposed. This approach, unlike classical ones, is based on the formulation of the unsupervised change-detection problem in terms of the Bayesian decision theory. In this context, an adaptive semi-parametric technique for the unsupervised estimation of the statistical terms associated with the gray levels of changed and unchanged pixels in a difference image is presented. Such a technique exploits the effectivenesses of two theoretically well-founded estimation procedures: the reduced Parzen estimate (RPE) procedure and the expectation-maximization (EM) algorithm. Then, thanks to the resulting estimates and to a Markov Random Field (MRF) approach used to model the spatial-contextual information contained in the multitemporal images considered, a change detection map is generated. The adaptive semi-parametric nature of the proposed technique allows its application to different kinds of remote-sensing images. Experimental results, obtained on two sets of multitemporal remote-sensing images acquired by two different sensors, confirm the validity of the proposed approach

Enhancing retinal images by nonlinear registration

Being able to image the human retina in high resolution opens a new era in many important fields, such as pharmacological research for retinal diseases, researches in human cognition, nervous system, metabolism and blood stream, to name a few. In this paper, we propose to share the knowledge acquired in the fields of optics and imaging in solar astrophysics in order to improve the retinal imaging at very high spatial resolution in the perspective to perform a medical diagnosis. The main purpose would be to assist health care practitioners by enhancing retinal images and detect abnormal features. We apply a nonlinear registration method using local correlation tracking to increase the field of view and follow structure evolutions using correlation techniques borrowed from solar astronomy technique expertise. Another purpose is to define the tracer of movements after analyzing local correlations to follow the proper motions of an image from one moment to another, such as changes in optical flows that would be of high interest in a medical diagnosis.Comment: 21 pages, 7 figures, submitted to Optics Communication