A multi-view approach to cDNA micro-array analysis

The official published version can be obtained from the link below.Microarray has emerged as a powerful technology that enables biologists to study thousands of genes simultaneously, therefore, to obtain a better understanding of the gene interaction and regulation mechanisms. This paper is concerned with improving the processes involved in the analysis of microarray image data. The main focus is to clarify an image's feature space in an unsupervised manner. In this paper, the Image Transformation Engine (ITE), combined with different filters, is investigated. The proposed methods are applied to a set of real-world cDNA images. The MatCNN toolbox is used during the segmentation process. Quantitative comparisons between different filters are carried out. It is shown that the CLD filter is the best one to be applied with the ITE.This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC) of the UK under Grant GR/S27658/01, the National Science Foundation of China under Innovative Grant 70621001, Chinese Academy of Sciences under Innovative Group Overseas Partnership Grant, the BHP Billiton Cooperation of Australia Grant, the International Science and Technology Cooperation Project of China under Grant 2009DFA32050 and the Alexander von Humboldt Foundation of Germany

Automated detection of extended sources in radio maps: progress from the SCORPIO survey

Automated source extraction and parameterization represents a crucial challenge for the next-generation radio interferometer surveys, such as those performed with the Square Kilometre Array (SKA) and its precursors. In this paper we present a new algorithm, dubbed CAESAR (Compact And Extended Source Automated Recognition), to detect and parametrize extended sources in radio interferometric maps. It is based on a pre-filtering stage, allowing image denoising, compact source suppression and enhancement of diffuse emission, followed by an adaptive superpixel clustering stage for final source segmentation. A parameterization stage provides source flux information and a wide range of morphology estimators for post-processing analysis. We developed CAESAR in a modular software library, including also different methods for local background estimation and image filtering, along with alternative algorithms for both compact and diffuse source extraction. The method was applied to real radio continuum data collected at the Australian Telescope Compact Array (ATCA) within the SCORPIO project, a pathfinder of the ASKAP-EMU survey. The source reconstruction capabilities were studied over different test fields in the presence of compact sources, imaging artefacts and diffuse emission from the Galactic plane and compared with existing algorithms. When compared to a human-driven analysis, the designed algorithm was found capable of detecting known target sources and regions of diffuse emission, outperforming alternative approaches over the considered fields.Comment: 15 pages, 9 figure

Video enhancement using adaptive spatio-temporal connective filter and piecewise mapping

This paper presents a novel video enhancement system based on an adaptive spatio-temporal connective (ASTC) noise filter and an adaptive piecewise mapping function (APMF). For ill-exposed videos or those with much noise, we first introduce a novel local image statistic to identify impulse noise pixels, and then incorporate it into the classical bilateral filter to form ASTC, aiming to reduce the mixture of the most two common types of noises - Gaussian and impulse noises in spatial and temporal directions. After noise removal, we enhance the video contrast with APMF based on the statistical information of frame segmentation results. The experiment results demonstrate that, for diverse low-quality videos corrupted by mixed noise, underexposure, overexposure, or any mixture of the above, the proposed system can automatically produce satisfactory results

Segmentation-assisted detection of dirt impairments in archived film sequences

A novel segmentation-assisted method for film dirt detection is proposed. We exploit the fact that film dirt manifests in the spatial domain as a cluster of connected pixels whose intensity differs substantially from that of its neighborhood and we employ a segmentation-based approach to identify this type of structure. A key feature of our approach is the computation of a measure of confidence attached to detected dirt regions which can be utilized for performance fine tuning. Another important feature of our algorithm is the avoidance of the computational complexity associated with motion estimation. Our experimental framework benefits from the availability of manually derived as well as objective ground truth data obtained using infrared scanning. Our results demonstrate that the proposed method compares favorably with standard spatial, temporal and multistage median filtering approaches and provides efficient and robust detection for a wide variety of test material

Listening for Sirens: Locating and Classifying Acoustic Alarms in City Scenes

This paper is about alerting acoustic event detection and sound source localisation in an urban scenario. Specifically, we are interested in spotting the presence of horns, and sirens of emergency vehicles. In order to obtain a reliable system able to operate robustly despite the presence of traffic noise, which can be copious, unstructured and unpredictable, we propose to treat the spectrograms of incoming stereo signals as images, and apply semantic segmentation, based on a Unet architecture, to extract the target sound from the background noise. In a multi-task learning scheme, together with signal denoising, we perform acoustic event classification to identify the nature of the alerting sound. Lastly, we use the denoised signals to localise the acoustic source on the horizon plane, by regressing the direction of arrival of the sound through a CNN architecture. Our experimental evaluation shows an average classification rate of 94%, and a median absolute error on the localisation of 7.5{\deg} when operating on audio frames of 0.5s, and of 2.5{\deg} when operating on frames of 2.5s. The system offers excellent performance in particularly challenging scenarios, where the noise level is remarkably high.Comment: 6 pages, 9 figure