Competitive dynamics of lexical innovations in multi-layer networks

We study the introduction of lexical innovations into a community of language users. Lexical innovations, i.e., new terms added to people's vocabulary, play an important role in the process of language evolution. Nowadays, information is spread through a variety of networks, including, among others, online and offline social networks and the World Wide Web. The entire system, comprising networks of different nature, can be represented as a multi-layer network. In this context, lexical innovations diffusion occurs in a peculiar fashion. In particular, a lexical innovation can undergo three different processes: its original meaning is accepted; its meaning can be changed or misunderstood (e.g., when not properly explained), hence more than one meaning can emerge in the population; lastly, in the case of a loan word, it can be translated into the population language (i.e., defining a new lexical innovation or using a synonym) or into a dialect spoken by part of the population. Therefore, lexical innovations cannot be considered simply as information. We develop a model for analyzing this scenario using a multi-layer network comprising a social network and a media network. The latter represents the set of all information systems of a society, e.g., television, the World Wide Web and radio. Furthermore, we identify temporal directed edges between the nodes of these two networks. In particular, at each time step, nodes of the media network can be connected to randomly chosen nodes of the social network and vice versa. In so doing, information spreads through the whole system and people can share a lexical innovation with their neighbors or, in the event they work as reporters, by using media nodes. Lastly, we use the concept of "linguistic sign" to model lexical innovations, showing its fundamental role in the study of these dynamics. Many numerical simulations have been performed.Comment: 23 pages, 19 figures, 1 tabl

Diffusion and Contagion in Networks with Heterogeneous Agents and Homophily

We study how a behavior (an idea, buying a product, having a disease, adopting a cultural fad or a technology) spreads among agents in an a social network that exhibits segregation or homophily (the tendency of agents to associate with others similar to themselves). Individuals are distinguished by their types (e.g., race, gender, age, wealth, religion, profession, etc.) which, together with biased interaction patterns, induce heterogeneous rates of adoption. We identify the conditions under which a behavior diffuses and becomes persistent in the population. These conditions relate to the level of homophily in a society, the underlying proclivities of various types for adoption or infection, as well as how each type interacts with its own type. In particular, we show that homophily can facilitate diffusion from a small initial seed of adopters.Comment: 18 pages, 1 figur

Traveling and pinned fronts in bistable reaction-diffusion systems on network

Traveling fronts and stationary localized patterns in bistable reaction-diffusion systems have been broadly studied for classical continuous media and regular lattices. Analogs of such non-equilibrium patterns are also possible in networks. Here, we consider traveling and stationary patterns in bistable one-component systems on random Erd\"os-R\'enyi, scale-free and hierarchical tree networks. As revealed through numerical simulations, traveling fronts exist in network-organized systems. They represent waves of transition from one stable state into another, spreading over the entire network. The fronts can furthermore be pinned, thus forming stationary structures. While pinning of fronts has previously been considered for chains of diffusively coupled bistable elements, the network architecture brings about significant differences. An important role is played by the degree (the number of connections) of a node. For regular trees with a fixed branching factor, the pinning conditions are analytically determined. For large Erd\"os-R\'enyi and scale-free networks, the mean-field theory for stationary patterns is constructed

Classes of random walks on temporal networks with competing timescales

Random walks find applications in many areas of science and are the heart of essential network analytic tools. When defined on temporal networks, even basic random walk models may exhibit a rich spectrum of behaviours, due to the co-existence of different timescales in the system. Here, we introduce random walks on general stochastic temporal networks allowing for lasting interactions, with up to three competing timescales. We then compare the mean resting time and stationary state of different models. We also discuss the accuracy of the mathematical analysis depending on the random walk model and the structure of the underlying network, and pay particular attention to the emergence of non-Markovian behaviour, even when all dynamical entities are governed by memoryless distributions.Comment: 16 pages, 5 figure

Active mechanics reveal molecular-scale force kinetics in living oocytes

Active diffusion of intracellular components is emerging as an important process in cell biology. This process is mediated by complex assemblies of molecular motors and cytoskeletal filaments that drive force generation in the cytoplasm and facilitate enhanced motion. The kinetics of molecular motors have been precisely characterized in-vitro by single molecule approaches, however, their in-vivo behavior remains elusive. Here, we study the active diffusion of vesicles in mouse oocytes, where this process plays a key role in nuclear positioning during development, and combine an experimental and theoretical framework to extract molecular-scale force kinetics (force, power-stroke, and velocity) of the in-vivo active process. Assuming a single dominant process, we find that the nonequilibrium activity induces rapid kicks of duration $\tau \sim$ 300 $\mu$s resulting in an average force of $F \sim$ 0.4 pN on vesicles in in-vivo oocytes, remarkably similar to the kinetics of in-vitro myosin-V. Our results reveal that measuring in-vivo active fluctuations allows extraction of the molecular-scale activity in agreement with single-molecule studies and demonstrates a mesoscopic framework to access force kinetics.Comment: 20 pages, 4 figures, see ancillary files for Supplementary Materials, * equally contributing author

Structure formation in active networks

Structure formation and constant reorganization of the actin cytoskeleton are key requirements for the function of living cells. Here we show that a minimal reconstituted system consisting of actin filaments, crosslinking molecules and molecular-motor filaments exhibits a generic mechanism of structure formation, characterized by a broad distribution of cluster sizes. We demonstrate that the growth of the structures depends on the intricate balance between crosslinker-induced stabilization and simultaneous destabilization by molecular motors, a mechanism analogous to nucleation and growth in passive systems. We also show that the intricate interplay between force generation, coarsening and connectivity is responsible for the highly dynamic process of structure formation in this heterogeneous active gel, and that these competing mechanisms result in anomalous transport, reminiscent of intracellular dynamics

Modelling cytoskeletal traffic: an interplay between passive diffusion and active transport

We introduce the totally asymmetric exclusion process with Langmuir kinetics (TASEP-LK) on a network as a microscopic model for active motor protein transport on the cytoskeleton, immersed in the diffusive cytoplasm. We discuss how the interplay between active transport along a network and infinite diffusion in a bulk reservoir leads to a heterogeneous matter distribution on various scales. We find three regimes for steady state transport, corresponding to the scale of the network, of individual segments or local to sites. At low exchange rates strong density heterogeneities develop between different segments in the network. In this regime one has to consider the topological complexity of the whole network to describe transport. In contrast, at moderate exchange rates the transport through the network decouples, and the physics is determined by single segments and the local topology. At last, for very high exchange rates the homogeneous Langmuir process dominates the stationary state. We introduce effective rate diagrams for the network to identify these different regimes. Based on this method we develop an intuitive but generic picture of how the stationary state of excluded volume processes on complex networks can be understood in terms of the single-segment phase diagram.Comment: 5 pages, 7 figure