Roadmap on optical security

Postprint (author's final draft

Wavefront shaping concepts for application in optical coherence tomography - a review

Optical coherence tomography (OCT) enables three-dimensional imaging with resolution on the micrometer scale. The technique relies on the time-of-flight gated detection of light scattered from a sample and has received enormous interest in applications as versatile as non-destructive testing, metrology and non-invasive medical diagnostics. However, in strongly scattering media such as biological tissue, the penetration depth and imaging resolution are limited. Combining OCT imaging with wavefront shaping approaches significantly leverages the capabilities of the technique by controlling the scattered light field through manipulation of the field incident on the sample. This article reviews the main concepts developed so far in the field and discusses the latest results achieved with a focus on signal enhancement and imaging. © 2020 by the authors. Licensee MDPI, Basel, Switzerland

Harnessing Spatial Intensity Fluctuations for Optical Imaging and Sensing

Properties of light such as amplitude and phase, temporal and spatial coherence, polarization, etc. are abundantly used for sensing and imaging. Regardless of the passive or active nature of the sensing method, optical intensity fluctuations are always present! While these fluctuations are usually regarded as noise, there are situations where one can harness the intensity fluctuations to enhance certain attributes of the sensing procedure. In this thesis, we developed different sensing methodologies that use statistical properties of optical fluctuations for gauging specific information. We examine this concept in the context of three different aspects of computational optical imaging and sensing. First, we study imposing specific statistical properties to the probing field to image or characterize certain properties of an object through a statistical analysis of the spatially integrated scattered intensity. This offers unique capabilities for imaging and sensing techniques operating in highly perturbed environments and low-light conditions. Next, we examine optical sensing in the presence of strong perturbations that preclude any controllable field modification. We demonstrate that inherent properties of diffused coherent fields and fluctuations of integrated intensity can be used to track objects hidden behind obscurants. Finally, we address situations where, due to coherent noise, image accuracy is severely degraded by intensity fluctuations. By taking advantage of the spatial coherence properties of optical fields, we show that this limitation can be effectively mitigated and that a significant improvement in the signal-to-noise ratio can be achieved even in one single-shot measurement. The findings included in this dissertation illustrate different circumstances where optical fluctuations can affect the efficacy of computational optical imaging and sensing. A broad range of applications, including biomedical imaging and remote sensing, could benefit from the new approaches to suppress, enhance, and exploit optical fluctuations, which are described in this dissertation

Roadmap on optical security

Information security and authentication are important challenges facing society. Recent attacks by hackers on the databases of large commercial and financial companies have demonstrated that more research and development of advanced approaches are necessary to deny unauthorized access to critical data. Free space optical technology has been investigated by many researchers in information security, encryption, and authentication. The main motivation for using optics and photonics for information security is that optical waveforms possess many complex degrees of freedom such as amplitude, phase, polarization, large bandwidth, nonlinear transformations, quantum properties of photons, and multiplexing that can be combined in many ways to make information encryption more secure and more difficult to attack. This roadmap article presents an overview of the potential, recent advances, and challenges of optical security and encryption using free space optics. The roadmap on optical security is comprised of six categories that together include 16 short sections written by authors who have made relevant contributions in this field. The first category of this roadmap describes novel encryption approaches, including secure optical sensing which summarizes double random phase encryption applications and flaws [Yamaguchi], the digital holographic encryption in free space optical technique which describes encryption using multidimensional digital holography [Nomura], simultaneous encryption of multiple signals [Pérez-Cabré], asymmetric methods based on information truncation [Nishchal], and dynamic encryption of video sequences [Torroba]. Asymmetric and one-way cryptosystems are analyzed by Peng. The second category is on compression for encryption. In their respective contributions, Alfalou and Stern propose similar goals involving compressed data and compressive sensing encryption. The very important area of cryptanalysis is the topic of the third category with two sections: Sheridan reviews phase retrieval algorithms to perform different attacks, whereas Situ discusses nonlinear optical encryption techniques and the development of a rigorous optical information security theory. The fourth category with two contributions reports how encryption could be implemented at the nano- or micro-scale. Naruse discusses the use of nanostructures in security applications and Carnicer proposes encoding information in a tightly focused beam. In the fifth category, encryption based on ghost imaging using single-pixel detectors is also considered. In particular, the authors [Chen, Tajahuerce] emphasize the need for more specialized hardware and image processing algorithms. Finally, in the sixth category, Mosk and Javidi analyze in their corresponding papers how quantum imaging can benefit optical encryption systems. Sources that use few photons make encryption systems much more difficult to attack, providing a secure method for authentication.Centro de Investigaciones ÓpticasConsejo Nacional de Investigaciones Científicas y Técnica

Optical Camera Communications: Principles, Modulations, Potential and Challenges

Optical wireless communications (OWC) are emerging as cost-effective and practical solutions to the congested radio frequency-based wireless technologies. As part of OWC, optical camera communications (OCC) have become very attractive, considering recent developments in cameras and the use of fitted cameras in smart devices. OCC together with visible light communications (VLC) is considered within the framework of the IEEE 802.15.7m standardization. OCCs based on both organic and inorganic light sources as well as cameras are being considered for low-rate transmissions and localization in indoor as well as outdoor short-range applications and within the framework of the IEEE 802.15.7m standardization together with VLC. This paper introduces the underlying principles of OCC and gives a comprehensive overview of this emerging technology with recent standardization activities in OCC. It also outlines the key technical issues such as mobility, coverage, interference, performance enhancement, etc. Future research directions and open issues are also presented

Light Microscopic Precise Measurements of Genome Structure during Tumorigenesis in Transgenic Mice

The higher order and spatial organisation of the genome is closely related to gene’s transcriptional activity. With the numerous results reported in this area, little is known about the precise information of specific chromatin structure, especially the dynamic during physiological changes and tumorigenesis, in the well-preserved tissue sections. In this work, thin tissue cryosections (about 200 nm in thickness) from the mammary gland of transgenic mice were used to study the genome organisation during the tumorigenesis process. Stereological methods were used to estimate the three-dimensional genome structure from the two-dimensional nuclear profiles. It was found that the whole genome-wide chromatin condensation state varies significantly during the tumorigenesis process. The existence of the extremely large as well as the highly condensed nuclei in the mammary tumor cryosections indicates the unique situation of malignancy. The relative volume fraction of chromosome 11 in the nucleus becomes smaller in the tumorigenesis process, while the nuclear radial position of the chromosome stays the same in this process. The central position of chromosome 11 is in good agreement with the gene density related chromosome radial positioning theory. Besides, some preliminary studies regarding the nuclear position and the condensation state of the viral oncogene SV40Tag have been demonstrated. In conclusion, this work presents the first effort to investigate genome organisation during the tumorigenesis process combining fluorescent in situ hybridisation and tissue cryosections. The parameters of specific genome structure measured in this work are the most precise values one can get from tissue sections so far

Acquisition and modeling of material appearance

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2006.Includes bibliographical references (p. 131-143).In computer graphics, the realistic rendering of synthetic scenes requires a precise description of surface geometry, lighting, and material appearance. While 3D geometry scanning and modeling have advanced significantly in recent years, measurement and modeling of accurate material appearance have remained critical challenges. Analytical models are the main tools to describe material appearance in most current applications. They provide compact and smooth approximations to real materials but lack the expressiveness to represent complex materials. Data-driven approaches based on exhaustive measurements are fully general but the measurement process is difficult and the storage requirement is very high. In this thesis, we propose the use of hybrid representations that are more compact and easier to acquire than exhaustive measurement, while preserving much generality of a data-driven approach. To represent complex bidirectional reflectance distribution functions (BRDFs), we present a new method to estimate a general microfacet distribution from measured data. We show that this representation is able to reproduce complex materials that are impossible to model with purely analytical models.(cont.) We also propose a new method that significantly reduces measurement cost and time of the bidirectional texture function (BTF) through a statistical characterization of texture appearance. Our reconstruction method combines naturally aligned images and alignment-insensitive statistics to produce visually plausible results. We demonstrate our acquisition system which is able to capture intricate materials like fabrics in less than ten minutes with commodity equipments. In addition, we present a method to facilitate effective user design in the space of material appearance. We introduce a metric in the space of reflectance which corresponds roughly to perceptual measures. The main idea of our approach is to evaluate reflectance differences in terms of their induced rendered images, instead of the reflectance function itself defined in the angular domains. With rendered images, we show that even a simple computational metric can provide good perceptual spacing and enable intuitive navigation of the reflectance space.by Wai Kit Addy Ngan.Ph.D

Cascaded Regression Tracking: Towards Online Hard Distractor Discrimination

Visual tracking can be easily disturbed by similar surrounding objects. Such objects as hard distractors, even though being the minority among negative samples, increase the risk of target drift and model corruption, which deserve additional attention in online tracking and model update. To enhance the tracking robustness, in this paper, we propose a cascaded regression tracker with two sequential stages. In the first stage, we filter out abundant easily-identified negative candidates via an efficient convolutional regression. In the second stage, a discrete sampling based ridge regression is designed to double-check the remaining ambiguous hard samples, which serves as an alternative of fully-connected layers and benefits from the closed-form solver for efficient learning. Extensive experiments are conducted on 11 challenging tracking benchmarks including OTB-2013, OTB-2015, VOT2018, VOT2019, UAV123, Temple-Color, NfS, TrackingNet, LaSOT, UAV20L, and OxUvA. The proposed method achieves state-of-the-art performance on prevalent benchmarks, while running in a real-time speed.Comment: Accepted by IEEE TCSV

Advancing combined radiological and optical scanning for breast-conserving surgery margin guidance

Breast cancer is one of the most common types of cancer worldwide, and standard-of-care for early-stage disease typically involves a lumpectomy or breast-conserving surgery (BCS). BCS involves the local resection of cancerous tissue, while sparring as much healthy tissue as possible. State-of-the-art methods for intraoperatively evaluating BCS margins are limited. Approximately 20% of BCS cases result in a tissue resection with cancer at or near the resection surface (i.e., a positive margin). A two-fold increase in ipsilateral breast cancer recurrence is associated with the presence of one or more positive margins. Consequently, positive margins often necessitate costly re-excision procedures to achieve a curative outcome. X-ray micro-computed tomography (CT) is emerging as a powerful ex vivo specimen imaging technology, as it provides robust three-dimensional sensing of tumor morphology rapidly. However, X-ray attenuation lacks contrast between soft tissues that are important for surgical decision making during BCS. Optical structured light imaging, including spatial frequency domain imaging and active line scan imaging, can act as adjuvant tools to complement micro-CT, providing wide field-of-view, non-contact sensing of relevant breast tissue subtypes on resection margins that cannot be differentiated by micro-CT alone. This thesis is dedicated to multimodal imaging of BCS tissues to ultimately improve intraoperative BCS margin assessment, reducing the number of positive margins after initial surgeries and thereby reducing the need for costly follow-up procedures. Volumetric sensing of micro-CT is combined with surface-weighted, sub-diffuse optical reflectance derived from high spatial frequency structured light imaging. Sub-diffuse reflectance plays the key role of providing enhanced contrast to a suite of normal, abnormal benign, and malignant breast tissue subtypes. This finding is corroborated through clinical studies imaging BCS specimen slices post-operatively and is further investigated through an observational clinical trial focused on combined, intraoperative micro-CT and optical imaging of whole, freshly resected BCS tumors. The central thesis of this work is that combining volumetric X-ray imaging and sub-diffuse optical scanning provides a synergistic multimodal imaging solution to margin assessment, one that can be readily implemented or retrofitted in X-ray specimen imaging systems and that could meaningfully improve surgical guidance during initial BCS procedures