126 research outputs found

    Minimally invasive aortic valve surgery

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    Since their introduction, it has been demonstrated that minimally invasive aortic valve replacement (MIAVR) approaches are safe and effective for the treatment of aortic valve diseases. To date, the main advantage of these approaches is represented by the reduced surgical trauma, with a subsequent reduced complication rate and faster recovery. This makes such approaches an appealing choice also for frail patients [obese, aged, chronic obstructive pulmonary disease (COPD)]. The standardization of the minimally invasive techniques, together with the implementation of preoperative workup and anesthesiological intraand post-operative care, led to an amelioration of surgical results and reduction of surgical times. Moreover, the improvement of surgical technology and the introduction of new devices such as sutureless and rapid deployment (SURD) valves, has helped the achievement of comparable results to traditional surgery. However, transcatheter technologies are nowadays more and more important in the treatment of aortic valve disease, also in low risk patients. For this reason surgeons should put new efforts for further reducing the surgical trauma in the future, even taking inspiration from other disciplines. In this review, we aim to present a review of literature evidences regarding minimally invasive treatment of aortic diseases, also reflecting our personal experience with MIAVR techniques. This review could represent a tool for a well-structured patient assessment and preoperative planning, in order to safely carrying out an MIAVR procedure with satisfactory outcomes

    Cardiac Surgery Procedures

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    Fusion of interventional ultrasound & X-ray

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    In einer immer älter werdenden Bevölkerung wird die Behandlung von strukturellen Herzkrankheiten zunehmend wichtiger. Verbesserte medizinische Bildgebung und die Einführung neuer Kathetertechnologien führten dazu, dass immer mehr herkömmliche chirurgische Eingriffe am offenen Herzen durch minimal invasive Methoden abgelöst werden. Diese modernen Interventionen müssen durch verschiedenste Bildgebungsverfahren navigiert werden. Hierzu werden hauptsächlich Röntgenfluoroskopie und transösophageale Echokardiografie (TEE) eingesetzt. Röntgen bietet eine gute Visualisierung der eingeführten Katheter, was essentiell für eine gute Navigation ist. TEE hingegen bietet die Möglichkeit der Weichteilgewebedarstellung und kann damit vor allem zur Darstellung von anatomischen Strukturen, wie z.B. Herzklappen, genutzt werden. Beide Modalitäten erzeugen Bilder in Echtzeit und werden für die erfolgreiche Durchführung minimal invasiver Herzchirurgie zwingend benötigt. Üblicherweise sind beide Systeme eigenständig und nicht miteinander verbunden. Es ist anzunehmen, dass eine Bildfusion beider Welten einen großen Vorteil für die behandelnden Operateure erzeugen kann, vor allem eine verbesserte Kommunikation im Behandlungsteam. Ebenso können sich aus der Anwendung heraus neue chirurgische Worfklows ergeben. Eine direkte Fusion beider Systeme scheint nicht möglich, da die Bilddaten eine zu unterschiedliche Charakteristik aufweisen. Daher kommt in dieser Arbeit eine indirekte Registriermethode zum Einsatz. Die TEE-Sonde ist während der Intervention ständig im Fluoroskopiebild sichtbar. Dadurch wird es möglich, die Sonde im Röntgenbild zu registrieren und daraus die 3D Position abzuleiten. Der Zusammenhang zwischen Ultraschallbild und Ultraschallsonde wird durch eine Kalibrierung bestimmt. In dieser Arbeit wurde die Methode der 2D-3D Registrierung gewählt, um die TEE Sonde auf 2D Röntgenbildern zu erkennen. Es werden verschiedene Beiträge präsentiert, welche einen herkömmlichen 2D-3D Registrieralgorithmus verbessern. Nicht nur im Bereich der Ultraschall-Röntgen-Fusion, sondern auch im Hinblick auf allgemeine Registrierprobleme. Eine eingeführte Methode ist die der planaren Parameter. Diese verbessert die Robustheit und die Registriergeschwindigkeit, vor allem während der Registrierung eines Objekts aus zwei nicht-orthogonalen Richtungen. Ein weiterer Ansatz ist der Austausch der herkömmlichen Erzeugung von sogenannten digital reconstructed radiographs. Diese sind zwar ein integraler Bestandteil einer 2D-3D Registrierung aber gleichzeitig sehr zeitaufwendig zu berechnen. Es führt zu einem erheblichen Geschwindigkeitsgewinn die herkömmliche Methode durch schnelles Rendering von Dreiecksnetzen zu ersetzen. Ebenso wird gezeigt, dass eine Kombination von schnellen lernbasierten Detektionsalgorithmen und 2D-3D Registrierung die Genauigkeit und die Registrierreichweite verbessert. Zum Abschluss werden die ersten Ergebnisse eines klinischen Prototypen präsentiert, welcher die zuvor genannten Methoden verwendet.Today, in an elderly community, the treatment of structural heart disease will become more and more important. Constant improvements of medical imaging technologies and the introduction of new catheter devices caused the trend to replace conventional open heart surgery by minimal invasive interventions. These advanced interventions need to be guided by different medical imaging modalities. The two main imaging systems here are X-ray fluoroscopy and Transesophageal  Echocardiography (TEE). While X-ray provides a good visualization of inserted catheters, which is essential for catheter navigation, TEE can display soft tissues, especially anatomical structures like heart valves. Both modalities provide real-time imaging and are necessary to lead minimal invasive heart surgery to success. Usually, the two systems are detached and not connected. It is conceivable that a fusion of both worlds can create a strong benefit for the physicians. It can lead to a better communication within the clinical team and can probably enable new surgical workflows. Because of the completely different characteristics of the image data, a direct fusion seems to be impossible. Therefore, an indirect registration of Ultrasound and X-ray images is used. The TEE probe is usually visible in the X-ray image during the described minimal-invasive interventions. Thereby, it becomes possible to register the TEE probe in the fluoroscopic images and to establish its 3D position. The relationship of the Ultrasound image to the Ultrasound probe is known by calibration. To register the TEE probe on 2D X-ray images, a 2D-3D registration approach is chosen in this thesis. Several contributions are presented, which are improving the common 2D-3D registration algorithm for the task of Ultrasound and X-ray fusion, but also for general 2D-3D registration problems. One presented approach is the introduction of planar parameters that increase robustness and speed during the registration of an object on two non-orthogonal views. Another approach is to replace the conventional generation of digital reconstructedradiographs, which is an integral part of 2D-3D registration but also a performance bottleneck, with fast triangular mesh rendering. This will result in a significant performance speed-up. It is also shown that a combination of fast learning-based detection algorithms with 2D-3D registration will increase the accuracy and the capture range, instead of employing them solely to the  registration/detection of a TEE probe. Finally, a first clinical prototype is presented which employs the presented approaches and first clinical results are shown

    Left Atrial Appendage Printing Process

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    The left atrial appendage senior design team aims to assist in closing off the left atrial appendage that is susceptible to coagulation due to non-valvular atrial fibrillation. Coagulation in the left atrial appendage (LAA) can be life threatening as it can lead to a stroke. Dr. Chris Porterfield performs a procedure that uses the Boston Scientific Watchman to close the appendage. He finds that sizing the Watchman properly is difficult with limited visuals from live CT scans. He proposed converting the CT scans into a 3D printed model of the left atrial appendage and left atrium so he can visually measure the opening and predict the trajectory angle of the Watchman device into the left atrial appendage. He currently has a base algorithm and procedure to convert and modify the CT scan into a .stl file, which can then be printed with standard PLA material using a 3D printer on Cal Poly’s campus. The project is limited to the printers and their material capabilities on Cal Poly’s campus. There are currently many programs that convert CT scans to printable files and this project aims to evaluate each to conclude which produces the most accurate 3D model. The procedure to create the model must also be quick to perform, repeatable and reproducible as well as easy to follow. After researching the various programs, we concluded that 3D Slicer allows us to print anatomically accurate models of the left atrium and LAA. Using this software, the user uploads CT scans obtained from the radiologist as a DICOM file. Once uploaded, the user will proceed to setting the threshold parameter to the designated values. The user will then scroll through the CT scan to identify the left atrium and LAA in one of the views. After locating the anatomies, the user will use the scissors tool to extrude out any unnecessary anatomy. Once isolated, the model will need to be hollowed out and set to the defined parameters. After a final cut is made to open the model for internal viewing, is it saved as a .stl file and sent to a 3D printing software such as Cura. From this point on, the user will refer to the printer’s manual for the printing procedure while using the parameters we listed as a guide. After the print is concluded, the user will be able to measure the opening of the LAA and determine which entry angle is most optimal. The key customer requirements we aimed to achieve were ease of use, time, production cost, shape/accuracy, repeatability and reproducibility. For ease of use, we had users go through our MPI, Training Guide and Operations Manual and had them rate between 1-10 on how clear and concise our directions were. We scaled the range so that 1 meant that our procedure was clear and concise enough to replicate while 10 meant it was near impossible to follow. We aimed to achieve an average score of less than 3. For time, we were given a timeframe of 24 hour to fully slice and print the model. Since this procedure is not officially ICD-9 billable yet, the cost of production must remain below $50 per print. Based on the sizing chart provided by Boston Scientific for the various sizes of the Watchman device, we decided that the shape/accuracy must be less than 10% variation from the CT scan, while the repeatability and reproducibility must have no statistical difference in variation from the ANOVA. After running ANOVA on the data obtained from measuring the 9 testing prints, the results showed that our slicing/printing procedure and the measurements taken for testing were adequate enough to prove the functionality of all our protocols. The results of ANOVA showed that there were no significant differences in our data except for depth reproducibility which means that our customer requirements of reproducibility and repeatability were almost met. For the ease of use requirement, Dr. Porterfield and his clinical specialist, Sarah Griess, went through our Manufacturing Process Instructions, 2 Training Guide, and Operations Manual and performed the feedback survey we provided. Based on those results, we concluded that our protocols are functional and easy to follow which is essential to producing an accurate model. To prove model accuracy, we had Dr. Porterfield size the Watchman device as he currently does and confirmed that our printed models were accurate

    Atrial fibrillation in high-risk patients

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    La fibrillation auriculaire (FA) est la plus fréquente des arythmies cardiaques. La FA est associée à un risque accru d’accident vasculaire cérébral, d’insuffisance cardiaque et de mortalité, constituant un problème de santé publique majeur. L’avènement de nouvelles technologies permettant une surveillance électrocardiographique a démontré une haute prévalence de FA subclinique ou silencieuse chez les patients âgés à haut risque. Récemment, plusieurs efforts et essais thérapeutiques ont été dirigés vers une identification et un traitement plus précoces de la FA chez ces patients. L’anticoagulation orale a bien prouvé son efficacité dans la prévention thromboembolique chez les patients qui présentent un haut risque thromboembolique, mais au prix d’une augmentation significative des événements hémorragiques, un risque qui s’élève régulièrement chez les patients âgés et avec une comorbidité importante. Au cours des dernières années, des nouvelles alternatives non-pharmacologiques dans la prévention thromboembolique ont été développées. La fermeture percutanée de l’auricule gauche, site de formation de la majorité (~90%) des thrombus, est progressivement devenue une alternative valable à l’anticoagulation chez des patients avec FA non valvulaire à haute risque hémorragique. L’expérience des opérateurs et les innovations technologiques ont permis une amélioration remarquable des résultats en ce qui concerne la sécurité et l’efficacité. Cependant, quelques questions restent sans réponse. Les préoccupations les plus débattues suite à la fermeture de l’auricule gauche sont la prise en charge de l’anticoagulation postprocédure et la prévention/gestion de la thrombose de dispositif. Les objectifs de ce travail de recherche sont : (i) évaluer la charge arythmique silencieuse chez des patients à haut risque à l’aide de l’utilisation de nouveaux systèmes d’enregistrement électrocardiographique prolongé, et (ii) analyser l'impact hémodynamique et thrombogénique de la fermeture percutanée de l'auricule gauche avec les dispositifs actuels et émergents.Atrial fibrillation (AF) is the most common cardiac arrhythmia. AF is associated with an increased risk of stroke, heart failure and mortality, posing a major public health problem. The advent of new technologies for continuous electrocardiographic monitoring has demonstrated a high incidence of subclinical or silent AF in elderly high-risk patients. Recently, several therapeutic efforts and studies have been directed towards earlier identification and treatment of AF in these patients. Oral anticoagulation has proven to be effective in preventing thromboembolism in patients at high thromboembolic risk, albeit at the expense of a significant increase in hemorrhagic events; a risk that increases steadily in elderly patients with high comorbidity burden. In recent years, novel non-pharmacological alternatives have been developed for thromboembolic prevention. Percutaneous left atrial appendage (LAA) closure, site of origin of the vast majority (~ 90%) of thrombi, has progressively become a valid alternative to anticoagulation in patients with non-valvular AF at high bleeding risk. Increasing operators' experience and technological innovations have led to remarkable improvements in the safety and efficacy of the procedure. However, some issues remain unanswered or controversial. Two of the most debated concerns are post-procedural antithrombotic management and device-related thrombosis (DRT) following LAA closure. The aims of the present research study are: (i) to evaluate the silent arrhythmic burden in high-risk patients using novel prolonged continuous electrocardiographic monitoring systems, and (ii) to assess the hemodynamic and thrombogenic impact of percutaneous LAA closure using current and emerging devices

    Abstracts - SA Heart Congress 2016

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    Index of abstracts: alphabetical listing of first authors

    Ventricular assist devices implantation: surgical assessment and technical strategies

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    Along with the worldwide increase in continuous left ventricular assist device (LVAD) strategy adoption, more and more patients with demanding anatomical and clinical features are currently referred to heart failure (HF) departments for treatment. Thus surgeons have to deal, technically, with re-entry due to previous cardiac surgery procedures, porcelain aorta, peripheral vascular arterial disease, concomitant valvular or septal disease, biventricular failure. New surgical techniques and surgical tools have been developed to offer acceptable postoperative outcomes to all mechanical circulatory support recipients. Several less invasive and/or thoracotomic approaches for surgery combined with various LVAD inflow and outflow graft alternative anastomotic sites for system placement have been reported and described to solve complex clinical scenarios. Surgical techniques have been upgraded with further technical tips to preserve the native anatomy in case of re-entry for heart transplantation, myocardial recovery or device explant. The current continuous-flow miniaturized and intrapericardial devices provide versatility and technical advantages. However, the surgical planning requires a careful multidisciplinary evaluation which must be driven by a dedicated and well-trained Heart Failure team. Biventricular assist device (BVAD) implantation by adoption of the newer radial pumps might be a challenge. However, the results are encouraging thus remaining a valid option. This paper reviews and summarizes LVAD preoperative assessment and current surgical techniques for implantation

    Iatrogenic trauma following percutaneous and minimally invasive surgical interventions

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    Technological progress has changed the landscape of surgical practice. Minimally invasive surgery (MIS) and percutaneous interventions (PC) are constantly replacing open procedures. This reduces hospital stay and allows quicker recovery. The application of MIS should follow the good medical practice dictum by Hippocrates i.e. First do no harm . To remain abreast with new procedures, the medical personnel are required to update and enhance their knowledge and skill. To ensure safety, the innovations are rigorously tested and tried. The learning curve of MIS is shortened by simulator training and proctorship. Credentialing processes are in place to enhance safe delivery of care. Despite of all these measures MIS and PCI are associated with adverse effects. The purpose of this article is to overview the iatrogenic trauma associated with MIS and PCI in major surgical subspecialties
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