A Patient-Adaptive Profiling Scheme for ECG Beat Classification

Recent trends in clinical and telemedicine applications highly demand automation in electrocardiogram (ECG) signal processing and heart beat classification. A patient-adaptive cardiac profiling scheme using repetition-detection concept is proposed in this paper. We first employ an efficient wavelet-based beat-detection mechanism to extract precise fiducial ECG points. Then, we implement a novel local ECG beat classifier to profile each patient's normal cardiac behavior. ECG morphologies vary from person to person and even for each person, it can vary over time depending on the person's physical condition and/or environment. Having such profile is essential for various diagnosis (e.g., arrhythmia) purposes. One application of such profiling scheme is to automatically raise an early warning flag for the abnormal cardiac behavior of any individual. Our extensive experimental results on the MIT-BIH arrhythmia database show that our technique can detect the beats with 99.59% accuracy and can identify abnormalities with a high classification accuracy of 97.42%

Wiki-health: from quantified self to self-understanding

Today, healthcare providers are experiencing explosive growth in data, and medical imaging represents a significant portion of that data. Meanwhile, the pervasive use of mobile phones and the rising adoption of sensing devices, enabling people to collect data independently at any time or place is leading to a torrent of sensor data. The scale and richness of the sensor data currently being collected and analysed is rapidly growing. The key challenges that we will be facing are how to effectively manage and make use of this abundance of easily-generated and diverse health data. This thesis investigates the challenges posed by the explosive growth of available healthcare data and proposes a number of potential solutions to the problem. As a result, a big data service platform, named Wiki-Health, is presented to provide a unified solution for collecting, storing, tagging, retrieving, searching and analysing personal health sensor data. Additionally, it allows users to reuse and remix data, along with analysis results and analysis models, to make health-related knowledge discovery more available to individual users on a massive scale. To tackle the challenge of efficiently managing the high volume and diversity of big data, Wiki-Health introduces a hybrid data storage approach capable of storing structured, semi-structured and unstructured sensor data and sensor metadata separately. A multi-tier cloud storage system—CACSS has been developed and serves as a component for the Wiki-Health platform, allowing it to manage the storage of unstructured data and semi-structured data, such as medical imaging files. CACSS has enabled comprehensive features such as global data de-duplication, performance-awareness and data caching services. The design of such a hybrid approach allows Wiki-Health to potentially handle heterogeneous formats of sensor data. To evaluate the proposed approach, we have developed an ECG-based health monitoring service and a virtual sensing service on top of the Wiki-Health platform. The two services demonstrate the feasibility and potential of using the Wiki-Health framework to enable better utilisation and comprehension of the vast amounts of sensor data available from different sources, and both show significant potential for real-world applications.Open Acces

Optimal Multi-Stage Arrhythmia Classification Approach

Arrhythmia constitutes a problem with the rate or rhythm of the heartbeat, and an early diagnosis is essential for the timely inception of successful treatment. We have jointly optimized the entire multi-stage arrhythmia classification scheme based on 12-lead surface ECGs that attains the accuracy performance level of professional cardiologists. The new approach is comprised of a three-step noise reduction stage, a novel feature extraction method and an optimal classification model with finely tuned hyperparameters. We carried out an exhaustive study comparing thousands of competing classification algorithms that were trained on our proprietary, large and expertly labeled dataset consisting of 12-lead ECGs from 40,258 patients with four arrhythmia classes: atrial fibrillation, general supraventricular tachycardia, sinus bradycardia and sinus rhythm including sinus irregularity rhythm. Our results show that the optimal approach consisted of Low Band Pass filter, Robust LOESS, Non Local Means smoothing, a proprietary feature extraction method based on percentiles of the empirical distribution of ratios of interval lengths and magnitudes of peaks and valleys, and Extreme Gradient Boosting Tree classifier, achieved an F1-Score of 0.988 on patients without additional cardiac conditions. The same noise reduction and feature extraction methods combined with Gradient Boosting Tree classifier achieved an F1-Score of 0.97 on patients with additional cardiac conditions. Our method achieved the highest classification accuracy (average 10-fold cross-validation F1-Score of 0.992) using an external validation data, MIT-BIH arrhythmia database. The proposed optimal multi-stage arrhythmia classification approach can dramatically benefit automatic ECG data analysis by providing cardiologist level accuracy and robust compatibility with various ECG data sources

HEART MONITORING VIA WIRELESS ECG

The monitoring of heart had been a complex task. Acquiring ECG of the chronic patient spending most of their time outside the hospital had been a trivial task. Recording of ECG of such patients using wireless method is further challenging. This paper presents various methods of wireless ECG acquisition, their limitations and challenges. Cardiomobile, Flexible wireless ECG are the examples of such systems that are available in the medical world for wireless ECG

Sensing and Signal Processing in Smart Healthcare

In the last decade, we have witnessed the rapid development of electronic technologies that are transforming our daily lives. Such technologies are often integrated with various sensors that facilitate the collection of human motion and physiological data and are equipped with wireless communication modules such as Bluetooth, radio frequency identification, and near-field communication. In smart healthcare applications, designing ergonomic and intuitive human–computer interfaces is crucial because a system that is not easy to use will create a huge obstacle to adoption and may significantly reduce the efficacy of the solution. Signal and data processing is another important consideration in smart healthcare applications because it must ensure high accuracy with a high level of confidence in order for the applications to be useful for clinicians in making diagnosis and treatment decisions. This Special Issue is a collection of 10 articles selected from a total of 26 contributions. These contributions span the areas of signal processing and smart healthcare systems mostly contributed by authors from Europe, including Italy, Spain, France, Portugal, Romania, Sweden, and Netherlands. Authors from China, Korea, Taiwan, Indonesia, and Ecuador are also included

ECG Classification with an Adaptive Neuro-Fuzzy Inference System

Heart signals allow for a comprehensive analysis of the heart. Electrocardiography (ECG or EKG) uses electrodes to measure the electrical activity of the heart. Extracting ECG signals is a non-invasive process that opens the door to new possibilities for the application of advanced signal processing and data analysis techniques in the diagnosis of heart diseases. With the help of today’s large database of ECG signals, a computationally intelligent system can learn and take the place of a cardiologist. Detection of various abnormalities in the patient’s heart to identify various heart diseases can be made through an Adaptive Neuro-Fuzzy Inference System (ANFIS) preprocessed by subtractive clustering. Six types of heartbeats are classified: normal sinus rhythm, premature ventricular contraction (PVC), atrial premature contraction (APC), left bundle branch block (LBBB), right bundle branch block (RBBB), and paced beats. The goal is to detect important characteristics of an ECG signal to determine if the patient’s heartbeat is normal or irregular. The results from three trials indicate an average accuracy of 98.10%, average sensitivity of 94.99%, and average specificity of 98.87%. These results are comparable to two artificial neural network (ANN) algorithms: gradient descent and Levenberg Marquardt, as well as the ANFIS preprocessed by grid partitioning

Applications of ECG Signal Analysis for R-R Complex Detection

By analyzing and profiling Electrocardiogram signals, we developed a technique for detecting abnormal heartbeats of any individual accurately and focusing on RR complex timestamps. With 96% - 116% range of precision for healthy patients, abnormalities were detected and arrhythmia diagnosed with 92.43% classification rate for 1-minute period evaluation. Studies in the bioelectrical activity of the heart and beat classification methods, in general, can help diagnosing heart diseases, besides being used as early warning signs for debilitated patients

ECG-Based Cardiac Assessment for Microgravity and High-Altitude Atmospheres

This research project focuses on the electrocardiogram (ECG) signal characteristics and introduces novel methods to identify certain types of arrhythmia and/or the onset of heart attack with high accuracy. This is especially important as fatal heart episodes have been reported in connection with takeoffs and landings as well as high-altitude atmospheres. Signal processing techniques will be employed to identify ECG characteristic feature points and then machine learning will be applied to classify the signal into healthy or classes of irregular ECG beats. The proposed techniques are intended to conveniently assist monitoring the heart functionality in conditions such as aerospace environments

Deep Generative Models: The winning key for large and easily accessible ECG datasets?

Large high-quality datasets are essential for building powerful artificial intelligence (AI) algorithms capable of supporting advancement in cardiac clinical research. However, researchers working with electrocardiogram (ECG) signals struggle to get access and/or to build one. The aim of the present work is to shed light on a potential solution to address the lack of large and easily accessible ECG datasets. Firstly, the main causes of such a lack are identified and examined. Afterward, the potentials and limitations of cardiac data generation via deep generative models (DGMs) are deeply analyzed. These very promising algorithms have been found capable not only of generating large quantities of ECG signals but also of supporting data anonymization processes, to simplify data sharing while respecting patients' privacy. Their application could help research progress and cooperation in the name of open science. However several aspects, such as a standardized synthetic data quality evaluation and algorithm stability, need to be further explored

Wearable and Nearable Biosensors and Systems for Healthcare

Biosensors and systems in the form of wearables and “nearables” (i.e., everyday sensorized objects with transmitting capabilities such as smartphones) are rapidly evolving for use in healthcare. Unlike conventional approaches, these technologies can enable seamless or on-demand physiological monitoring, anytime and anywhere. Such monitoring can help transform healthcare from the current reactive, one-size-fits-all, hospital-centered approach into a future proactive, personalized, decentralized structure. Wearable and nearable biosensors and systems have been made possible through integrated innovations in sensor design, electronics, data transmission, power management, and signal processing. Although much progress has been made in this field, many open challenges for the scientific community remain, especially for those applications requiring high accuracy. This book contains the 12 papers that constituted a recent Special Issue of Sensors sharing the same title. The aim of the initiative was to provide a collection of state-of-the-art investigations on wearables and nearables, in order to stimulate technological advances and the use of the technology to benefit healthcare. The topics covered by the book offer both depth and breadth pertaining to wearable and nearable technology. They include new biosensors and data transmission techniques, studies on accelerometers, signal processing, and cardiovascular monitoring, clinical applications, and validation of commercial devices