920 research outputs found
Texture descriptors applied to digital mammography
Breast cancer is the second cause of death among women cancers. Computer Aided Detection has been demon- strated an useful tool for early diagnosis, a crucial as- pect for a high survival rate. In this context, several re- search works have incorporated texture features in mam- mographic image segmentation and description such as Gray-Level co-occurrence matrices, Local Binary Pat- terns, and many others. This paper presents an approach for breast density classi¯cation based on segmentation and texture feature extraction techniques in order to clas- sify digital mammograms according to their internal tis- sue. The aim of this work is to compare di®erent texture descriptors on the same framework (same algorithms for segmentation and classi¯cation, as well as same images). Extensive results prove the feasibility of the proposed ap- proach.Postprint (published version
Breast Cancer Classification using Deep Learned Features Boosted with Handcrafted Features
Breast cancer is one of the leading causes of death among women across the
globe. It is difficult to treat if detected at advanced stages, however, early
detection can significantly increase chances of survival and improves lives of
millions of women. Given the widespread prevalence of breast cancer, it is of
utmost importance for the research community to come up with the framework for
early detection, classification and diagnosis. Artificial intelligence research
community in coordination with medical practitioners are developing such
frameworks to automate the task of detection. With the surge in research
activities coupled with availability of large datasets and enhanced
computational powers, it expected that AI framework results will help even more
clinicians in making correct predictions. In this article, a novel framework
for classification of breast cancer using mammograms is proposed. The proposed
framework combines robust features extracted from novel Convolutional Neural
Network (CNN) features with handcrafted features including HOG (Histogram of
Oriented Gradients) and LBP (Local Binary Pattern). The obtained results on
CBIS-DDSM dataset exceed state of the art
Deep Learning for Automated Medical Image Analysis
Medical imaging is an essential tool in many areas of medical applications,
used for both diagnosis and treatment. However, reading medical images and
making diagnosis or treatment recommendations require specially trained medical
specialists. The current practice of reading medical images is labor-intensive,
time-consuming, costly, and error-prone. It would be more desirable to have a
computer-aided system that can automatically make diagnosis and treatment
recommendations. Recent advances in deep learning enable us to rethink the ways
of clinician diagnosis based on medical images. In this thesis, we will
introduce 1) mammograms for detecting breast cancers, the most frequently
diagnosed solid cancer for U.S. women, 2) lung CT images for detecting lung
cancers, the most frequently diagnosed malignant cancer, and 3) head and neck
CT images for automated delineation of organs at risk in radiotherapy. First,
we will show how to employ the adversarial concept to generate the hard
examples improving mammogram mass segmentation. Second, we will demonstrate how
to use the weakly labeled data for the mammogram breast cancer diagnosis by
efficiently design deep learning for multi-instance learning. Third, the thesis
will walk through DeepLung system which combines deep 3D ConvNets and GBM for
automated lung nodule detection and classification. Fourth, we will show how to
use weakly labeled data to improve existing lung nodule detection system by
integrating deep learning with a probabilistic graphic model. Lastly, we will
demonstrate the AnatomyNet which is thousands of times faster and more accurate
than previous methods on automated anatomy segmentation.Comment: PhD Thesi
Computer aided diagnosis system for breast cancer using deep learning.
The recent rise of big data technology surrounding the electronic systems and developed toolkits gave birth to new promises for Artificial Intelligence (AI). With the continuous use of data-centric systems and machines in our lives, such as social media, surveys, emails, reports, etc., there is no doubt that data has gained the center of attention by scientists and motivated them to provide more decision-making and operational support systems across multiple domains. With the recent breakthroughs in artificial intelligence, the use of machine learning and deep learning models have achieved remarkable advances in computer vision, ecommerce, cybersecurity, and healthcare. Particularly, numerous applications provided efficient solutions to assist radiologists and doctors for medical imaging analysis, which has remained the essence of the visual representation that is used to construct the final observation and diagnosis. Medical research in cancerology and oncology has been recently blended with the knowledge gained from computer engineering and data science experts. In this context, an automatic assistance or commonly known as Computer-aided Diagnosis (CAD) system has become a popular area of research and development in the last decades. As a result, the CAD systems have been developed using multidisciplinary knowledge and expertise and they have been used to analyze the patient information to assist clinicians and practitioners in their decision-making process. Treating and preventing cancer remains a crucial task that radiologists and oncologists face every day to detect and investigate abnormal tumors. Therefore, a CAD system could be developed to provide decision support for many applications in the cancer patient care processes, such as lesion detection, characterization, cancer staging, tumors assessment, recurrence, and prognosis prediction. Breast cancer has been considered one of the common types of cancers in females across the world. It was also considered the leading cause of mortality among women, and it has been increased drastically every year. Early detection and diagnosis of abnormalities in screened breasts has been acknowledged as the optimal solution to examine the risk of developing breast cancer and thus reduce the increasing mortality rate. Accordingly, this dissertation proposes a new state-of-the-art CAD system for breast cancer diagnosis that is based on deep learning technology and cutting-edge computer vision techniques. Mammography screening has been recognized as the most effective tool to early detect breast lesions for reducing the mortality rate. It helps reveal abnormalities in the breast such as Mass lesion, Architectural Distortion, Microcalcification. With the number of daily patients that were screened is continuously increasing, having a second reading tool or assistance system could leverage the process of breast cancer diagnosis. Mammograms could be obtained using different modalities such as X-ray scanner and Full-Field Digital mammography (FFDM) system. The quality of the mammograms, the characteristics of the breast (i.e., density, size) or/and the tumors (i.e., location, size, shape) could affect the final diagnosis. Therefore, radiologists could miss the lesions and consequently they could generate false detection and diagnosis. Therefore, this work was motivated to improve the reading of mammograms in order to increase the accuracy of the challenging tasks. The efforts presented in this work consists of new design and implementation of neural network models for a fully integrated CAD system dedicated to breast cancer diagnosis. The approach is designed to automatically detect and identify breast lesions from the entire mammograms at a first step using fusion models’ methodology. Then, the second step only focuses on the Mass lesions and thus the proposed system should segment the detected bounding boxes of the Mass lesions to mask their background. A new neural network architecture for mass segmentation was suggested that was integrated with a new data enhancement and augmentation technique. Finally, a third stage was conducted using a stacked ensemble of neural networks for classifying and diagnosing the pathology (i.e., malignant, or benign), the Breast Imaging Reporting and Data System (BI-RADS) assessment score (i.e., from 2 to 6), or/and the shape (i.e., round, oval, lobulated, irregular) of the segmented breast lesions. Another contribution was achieved by applying the first stage of the CAD system for a retrospective analysis and comparison of the model on Prior mammograms of a private dataset. The work was conducted by joining the learning of the detection and classification model with the image-to-image mapping between Prior and Current screening views. Each step presented in the CAD system was evaluated and tested on public and private datasets and consequently the results have been fairly compared with benchmark mammography datasets. The integrated framework for the CAD system was also tested for deployment and showcase. The performance of the CAD system for the detection and identification of breast masses reached an overall accuracy of 97%. The segmentation of breast masses was evaluated together with the previous stage and the approach achieved an overall performance of 92%. Finally, the classification and diagnosis step that defines the outcome of the CAD system reached an overall pathology classification accuracy of 96%, a BIRADS categorization accuracy of 93%, and a shape classification accuracy of 90%. Results given in this dissertation indicate that our suggested integrated framework might surpass the current deep learning approaches by using all the proposed automated steps. Limitations of the proposed work could occur on the long training time of the different methods which is due to the high computation of the developed neural networks that have a huge number of the trainable parameters. Future works can include new orientations of the methodologies by combining different mammography datasets and improving the long training of deep learning models. Moreover, motivations could upgrade the CAD system by using annotated datasets to integrate more breast cancer lesions such as Calcification and Architectural distortion. The proposed framework was first developed to help detect and identify suspicious breast lesions in X-ray mammograms. Next, the work focused only on Mass lesions and segment the detected ROIs to remove the tumor’s background and highlight the contours, the texture, and the shape of the lesions. Finally, the diagnostic decision was predicted to classify the pathology of the lesions and investigate other characteristics such as the tumors’ grading assessment and type of the shape. The dissertation presented a CAD system to assist doctors and experts to identify the risk of breast cancer presence. Overall, the proposed CAD method incorporates the advances of image processing, deep learning, and image-to-image translation for a biomedical application
Modelling of Hybrid Meta heuristic Based Parameter Optimizers with Deep Convolutional Neural Network for Mammogram Cancer Detection
Breast cancer (BC) is the common type of cancer among females. Mortality from BC could be decreased by identifying and diagnosing it atan earlierphase. Different imaging modalities are used to detect BC, like mammography. Even withproven records as a BC screening tool, mammography istime-consuming and hasconstraints, namely lower sensitivity in women with dense breast tissue. Computer-Aided Diagnosis or Detection (CAD) system assistsaproficient radiologist to identifyBC at an earlier stage. Recently, the advancementin deep learning (DL)methodsareemployed to mammography assist radiologists to increase accuracy and efficiency. Therefore, this study presents a metaheuristic-based hyperparameter optimization with deep learning-based breast cancer detection on mammogram images (MHODL-BCDMI) technique. The presented MHODL-BCDMI technique mainly focused on the recognition and classification of breast cancer on digital mammograms. To achieve this, the MHODL-BCDMI technique employs pre-processing in two stages: Wiener Filter (WF) based noise elimination and contrast enhancement. Besides, the MHODL-BCDMI technique exploits densely connected networks (DenseNet201) model for feature extraction purposes. For BC classification and detection, a hybrid convolutional neural network with a gated recurrent unit (HCNN-GRU) model is used. Furthermore, three hyperparameter optimizers are employed namely cat swarm optimization (CSO), harmony search algorithm (HSA), and hybrid grey wolf whale optimization algorithm (HGWWOA). Finally, the U2Net segmentation approach is used for the classification of benign and malignant types of cancer. The experimental analysis of the MHODL-BCDMI method is tested on a digital mammogram image dataset and the outcomes are assessed in terms of diverse metrics. The simulation results highlighted the enhanced cancer detection performance of the MHODL-BCDMI technique over other recent algorithms
Breast cancer diagnosis: a survey of pre-processing, segmentation, feature extraction and classification
Machine learning methods have been an interesting method in the field of medical for many years, and they have achieved successful results in various fields of medical science. This paper examines the effects of using machine learning algorithms in the diagnosis and classification of breast cancer from mammography imaging data. Cancer diagnosis is the identification of images as cancer or non-cancer, and this involves image preprocessing, feature extraction, classification, and performance analysis. This article studied 93 different references mentioned in the previous years in the field of processing and tries to find an effective way to diagnose and classify breast cancer. Based on the results of this research, it can be concluded that most of today’s successful methods focus on the use of deep learning methods. Finding a new method requires an overview of existing methods in the field of deep learning methods in order to make a comparison and case study
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