A neural probe with up to 966 electrodes and up to 384 configurable channels in 0.13 μm SOI CMOS

In vivo recording of neural action-potential and local-field-potential signals requires the use of high-resolution penetrating probes. Several international initiatives to better understand the brain are driving technology efforts towards maximizing the number of recording sites while minimizing the neural probe dimensions. We designed and fabricated (0.13-μm SOI Al CMOS) a 384-channel configurable neural probe for large-scale in vivo recording of neural signals. Up to 966 selectable active electrodes were integrated along an implantable shank (70 μm wide, 10 mm long, 20 μm thick), achieving a crosstalk of −64.4 dB. The probe base (5 × 9 mm2) implements dual-band recording and a 1

±0.3V Bulk-Driven Fully Differential Buffer with High Figures of Merit

A high performance bulk-driven rail-to-rail fully differential buffer operating from ±0.3V supplies in 180 nm CMOS technology is reported. It has a differential–difference input stage and common mode feedback circuits implemented with no-tail, high CMRR bulk-driven pseudo-differential cells. It operates in subthreshold, has infinite input impedance, low output impedance (1.4 kΩ), 86.77 dB DC open-loop gain, 172.91 kHz bandwidth and 0.684 μW static power dissipation with a 50-pF load capacitance. The buffer has power efficient class AB operation, a small signal figure of merit FOMSS = 12.69 MHzpFμW−1, a large signal figure of merit FOMLS = 34.89 (V/μs) pFμW−1, CMRR = 102 dB, PSRR+ = 109 dB, PSRR− = 100 dB, 1.1 μV/√Hz input noise spectral density, 0.3 mVrms input noise and 3.5 mV input DC offset voltage.Junta de Andalucía - Consejería de Economía, Conocimiento, Empresas y Universidades P18-FR-4317Agencia Estatal de Investigación - FEDER PID2019-107258RB-C3

A Novel Fully Differential Second Generation Current Conveyor and Its Application as a Very High CMRR Instrumentation Amplifier

This paper aims to introduce a novel Fully Differential second generation Current Conveyor (FDCCII) and its application to design a novel Low Power (LP), very high CMRR, and wide bandwidth (BW) Current Mode Instrumentation Amplifier (CMIA). In the proposed application, CMRR, as the most important feature, has been greatly improved by using both common mode feed forward (CMFF) and common mode feedback (CMFB) techniques, which are verified by a perfect circuit analysis. As another unique quality, it neither needs well-matched active blocks nor matched resistors but inherently improves CMRR, BW, and power consumption hence gains an excellent matchless choice for integration. The FDCCII has been designed using 0.18 um TSMC CMOS Technology with ±1.2 V supply voltages. The simulation of the proposed FDCCII and CMIA have been done in HSPICE LEVEL 49. Simulation results for the proposed CMIA are as follow: Voltage CMRR of 216 dB, voltage CMRR BW of 300 Hz. Intrinsic resistance of X-terminals is only 45 Ω and the power dissipation is 383.4 μW.  Most favourably, it shows a constant differential voltage gain BW of 18.1 MHz for variable gains (here ranging from 0 dB to 45.7 dB for example) removing the bottleneck of constant gain-BW product of Voltage mode circuits

A HIGH PERFORMANCE FULLY DIFFERENTIAL PURE CURRENT MODE OPERATIONAL AMPLIFIER AND ITS APPLICATIONS

In this paper a novel high performance all current-mode fully-differential (FD) Current mode Operational Amplifier (COA) in BIPOLAR technology is presented. The unique true current mode simple structure grants the proposed COA the largest yet reported unity gain frequency while providing low voltage low power operation. Benefiting from some novel ideas, it also exhibits high gain, high common mode rejection ratio (CMRR), high power supply rejection ratio (PSRR), high output impedance, low input impedance and most importantly high current drive capability. Its most important parameters are derived and its performance is proved by PSPICE simulations using 0.8 μm BICMOS process parameters at supply voltage of ±1.2V indicating the values of 82.4 dB,52.3º, 31.5 Ω, 31.78 MΩ, 179.2 dB, 2 mW and 698 MHz for gain, phase margin, input impedance, output impedance, CMRR, power and unity gain frequency respectively. Its CMRR also shows very high frequency of 2.64 GHz at zero dB. Its very high PSRR+/PSRR- of 182 dB/196 dB makes the proposed COA a highly suitable block in Mixed-Mode (SOC) chips. Most favourably it can deliver up to ±1.5 mA yielding a high current drive capability exceeding 25. To demonstrate the performance of the proposed COA, it is used to realize a constant bandwidth voltage amplifier and a high performance Rm amplifier

A 0.3 V rail-to-rail ultra-low-power OTA with improved bandwidth and slew rate

In this paper, we present a novel operational transconductance amplifier (OTA) topology based on a dual-path body-driven input stage that exploits a body-driven current mirror-active load and targets ultra-low-power (ULP) and ultra-low-voltage (ULV) applications, such as IoT or biomedical devices. The proposed OTA exhibits only one high-impedance node, and can therefore be compensated at the output stage, thus not requiring Miller compensation. The input stage ensures rail-to-rail input common-mode range, whereas the gate-driven output stage ensures both a high open-loop gain and an enhanced slew rate. The proposed amplifier was designed in an STMicroelectronics 130 nm CMOS process with a nominal supply voltage of only 0.3 V, and it achieved very good values for both the small-signal and large-signal Figures of Merit. Extensive PVT (process, supply voltage, and temperature) and mismatch simulations are reported to prove the robustness of the proposed amplifier

A novel fully differential biopotential amplifier with DC suppression

Fully differential amplifiers yield large differential gains and also high common mode rejection ratio (CMRR), provided they do not include any unmatched grounded component. In biopotential measurements, however, the admissible gain of amplification stages located before dc suppression is usually limited by electrode offset voltage, which can saturate amplifier outputs. The standard solution is to first convert the differential input voltage to a single-ended voltage and then implement any other required functions, such as dc suppression and dc level restoring. This approach, however, yields a limited CMRR and may result in a relatively large equivalent input noise. This paper describes a novel fully differential biopotential amplifier based on a fully differential dc-suppression circuit that does not rely on any matched passive components, yet provides large CMRR and fast recovery from dc level transients. The proposed solution is particularly convenient for low supply voltage systems. An example implementation, based on standard low-power op amps and a single 5-V power supply, accepts input offset voltages up to /spl plusmn/500 mV, yields a CMRR of 102dB at 50 Hz, and provides, in accordance with the AAMI EC38 standard, a reset behavior for recovering from overloads or artifactsPeer Reviewe

A 122 fps, 1 MHz bandwidth multi-frequency wearable EIT belt featuring novel active electrode architecture for neonatal thorax vital sign monitoring

A highly integrated, wearable electrical impedance tomography (EIT) belt for neonatal thorax vital multiple sign monitoring is presented. The belt has sixteen active electrodes. Each has an application specific integrated circuit (ASIC) connected to an electrode. The ASIC contains a fully differential current driver, a high-performance instrumentation amplifier (IA), a digital controller and multiplexors. The wearable EIT belt features a new active electrode architecture that allows programmable flexible electrode current drive and voltage sense patterns under simple digital control. It provides intimate connections to the electrodes for the current drive and to the IA for direct differential voltage measurement providing superior common-mode rejection ratio. The ASIC was designed in a CMOS 0.35-μm high-voltage technology. The high specification EIT belt has an image frame rate of 122 fps, a wide operating bandwidth of 1 MHz and multi-frequency operation. It measures impedance with 98% accuracy and has less than 0.5 Ω and 1o variation across all possible channels. The image results confirmed the advantage of the new active electrode architecture and the benefit of wideband, multi-frequency EIT operation. The wearable EIT belt can also detect patient position and torso shape information using a MEMS sensor interfaced to each ASIC. The system successfully captured high quality lung respiration EIT images, breathing cycle and heart rate