172 research outputs found

    E-infrastructures fostering multi-centre collaborative research into the intensive care management of patients with brain injury

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    Clinical research is becoming ever more collaborative with multi-centre trials now a common practice. With this in mind, never has it been more important to have secure access to data and, in so doing, tackle the challenges of inter-organisational data access and usage. This is especially the case for research conducted within the brain injury domain due to the complicated multi-trauma nature of the disease with its associated complex collation of time-series data of varying resolution and quality. It is now widely accepted that advances in treatment within this group of patients will only be delivered if the technical infrastructures underpinning the collection and validation of multi-centre research data for clinical trials is improved. In recognition of this need, IT-based multi-centre e-Infrastructures such as the Brain Monitoring with Information Technology group (BrainIT - www.brainit.org) and Cooperative Study on Brain Injury Depolarisations (COSBID - www.cosbid.de) have been formed. A serious impediment to the effective implementation of these networks is access to the know-how and experience needed to install, deploy and manage security-oriented middleware systems that provide secure access to distributed hospital based datasets and especially the linkage of these data sets across sites. The recently funded EU framework VII ICT project Advanced Arterial Hypotension Adverse Event prediction through a Novel Bayesian Neural Network (AVERT-IT) is focused upon tackling these challenges. This chapter describes the problems inherent to data collection within the brain injury medical domain, the current IT-based solutions designed to address these problems and how they perform in practice. We outline how the authors have collaborated towards developing Grid solutions to address the major technical issues. Towards this end we describe a prototype solution which ultimately formed the basis for the AVERT-IT project. We describe the design of the underlying Grid infrastructure for AVERT-IT and how it will be used to produce novel approaches to data collection, data validation and clinical trial design is also presented

    Supporting security-oriented, inter-disciplinary research: crossing the social, clinical and geospatial domains

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    How many people have had a chronic disease for longer than 5-years in Scotland? How has this impacted upon their choices of employment? Are there any geographical clusters in Scotland where a high-incidence of patients with such long-term illness can be found? How does the life expectancy of such individuals compare with the national averages? Such questions are important to understand the health of nations and the best ways in which health care should be delivered and measured for their impact and success. In tackling such research questions, e-Infrastructures need to provide tailored, secure access to an extensible range of distributed resources including primary and secondary e-Health clinical data; social science data, and geospatial data sets amongst numerous others. In this paper we describe the security models underlying these e-Infrastructures and demonstrate their implementation in supporting secure, federated access to a variety of distributed and heterogeneous data sets exploiting the results of a variety of projects at the National e-Science Centre (NeSC) at the University of Glasgow

    An identity aware wimax personalization for pervasive computing services

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    Mobile Internet access is becoming more and more pervasive in the new 4G scenarios, where WiMAX is to play a crucial role. WiMax has advantages when considering both energy consumption and bandwidth, when compared with HSDPA and LTE. However, we have found some limitations in IEEE 802.16 security support, which may limit authentication and authorization mechanisms for ubiquitous service development. In this article we analyze weaknesses and vulnerabilities we have found in WiMAX security. WiMax, with the adequate identity management support, could be invaluable for developing new pervasive computing services. We propose the introduction of identity management in WiMAX, as a pervious step to the definition of identity aware WiMax personalization of pervasive computing servicesProyecto CCG10-UC3M/TIC-4992 de la Comunidad AutĂłnoma de Madrid y la Universidad Carlos III de Madri

    SeamlessAccess.org: Delivering a Simpler, Privacy-Preserving Access Experience

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    Managing access to subscribed services in an era of abundance is a major challenge for libraries. Users have come to expect a seamless, personalized experience on their mobile devices, but traditional approaches to access management force librarians to choose between the anonymous ease of on-site IP authentication or the access friction experienced by users authenticating via a proxy server or across multiple resources with Single Sign-On. Building on the work of the RA21 initiative, a recent NISO Recommended Practice on Improved Access to Institutionally Provided Information Resources, Seamless Access charts a way forward. It will enable libraries to provide seamless, privacy-preserving, and one-click access to subscribed content from any device, any location, and from any starting point in the research process. Seamless Access builds on both RA21 and the NISO Recommended Practice and is currently in a beta phase implementation. But how is user and data privacy protected, how is access simplified, and how is Seamless Access helping libraries implement this service? This chapter discusses how these concerns are being addressed by a consortium of industry partners including librarians, access providers, publishers, and standards organizations. It also discusses how Seamless Access will manage this service for publishers and libraries while continuing to improve this user experience, provide governance on data policy and privacy issues, and maintain core web services specific to this initiative

    A Federation of Language Archives Enabling Future eHumanities Scenarios

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    This paper describes the need for new infrastructures for future eScience scenarios in the humanities. Three projects working on different aspects of these infrastructures are examined in detail. The first project is trying to achieve a federation of archives, developing an integration layer at the level of localization, access to and referring to an archive’s raw data objects. The other two try to achieve interoperability at the level of semantic interpretation of linguistic data-types and tagging systems. The project’s different approaches to this problem show the trade-of between flexibility and the user’s workload. All three approaches give an impression about the necessary steps to come to an eHumanities scenario

    Leveraging Federated Authentication to Simplify Access: Understanding Changes in Access Mechanisms to Online Content

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    The COVID-19 pandemic is profoundly reshaping access to education and one of the areas impacted is access to electronic resources. While remote access has been a feature of our industry for decades, it was generally viewed as the exception. Now all of us have become remote users. This paper uses case studies to re-examine the remote access experiences of three libraries that navigated the shift to majority (or exclusive) remote access and how federated access has proven to save time and money for both small and large institutions alike. It also presents the genesis and ongoing evolution of the SeamlessAccess project, addresses privacy concerns related to accessing online content, and identifies potentially disruptive changes in browser technologies that are on the horizon

    Distributed authentication for the Western Australian University Libraries

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    The need to establish a means of achieving reliable, automated inter-institutional authentication was identified by the Western Australian Group of University Librarians (WAGUL) in 1999 as a strategic priority and a project was subsequently established as a result of a substantial grant from the Commonwealth Development Pool (CDP). The WAGUL Authentication Project (WALAP) first reported on its progress at VALA 2002 and now follows up with a report on the achievements to date and the challenges to come

    Supporting UK-wide e-clinical trials and studies

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    As clinical trials and epidemiological studies become increasingly large, covering wider (national) geographical areas and involving ever broader populations, the need to provide an information management infrastructure that can support such endeavours is essential. A wealth of clinical data now exists at varying levels of care (primary care, secondary care, etc.). Simple, secure access to such data would greatly benefit the key processes involved in clinical trials and epidemiological studies: patient recruitment, data collection and study management. The Grid paradigm provides one model for seamless access to such data and support of these processes. The VOTES project (Virtual Organisations for Trials and Epidemiological Studies) is a collaboration between several UK institutions to implement a generic framework that effectively leverages the available health-care information across the UK to support more efficient gathering and processing of trial information. The structure of the information available in the health-care domain in the UK itself varies broadly in-line with the national boundaries of the constituent states (England, Scotland, Wales and Northern Ireland). Technologies must address these political boundaries and the impact these boundaries have in terms of for example, information governance, policies, and of course large-scale heterogeneous distribution of the data sets themselves. This paper outlines the methodology in implementing the framework between three specific data sources that serve as useful case studies: Scottish data from the Scottish Care Information (SCI) Store data repository, data on the General Practice Research Database (GPRD) diabetes trial at Imperial College London, and benign prostate hypoplasia (BPH) data from the University of Nottingham. The design, implementation and wider research issues are discussed along with the technological challenges encountered in the project in the application of Grid technologies
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