Towards 3D facial morphometry:facial image analysis applications in anesthesiology and 3D spectral nonrigid registration

In anesthesiology, the detection and anticipation of difficult tracheal intubation is crucial for patient safety. When undergoing general anesthesia, a patient who is unexpectedly difficult to intubate risks potential life-threatening complications with poor clinical outcomes, ranging from severe harm to brain damage or death. Conversely, in cases of suspected difficulty, specific equipment and personnel will be called upon to increase safety and the chances of successful intubation. Research in anesthesiology has associated a certain number of morphological features of the face and neck with higher risk of difficult intubation. Detecting and analyzing these and other potential features, thus allowing the prediction of difficulty of tracheal intubation in a robust, objective, and automatic way, may therefore improve the patients' safety. In this thesis, we first present a method to automatically classify images of the mouth cavity according to the visibility of certain oropharyngeal structures. This method is then integrated into a novel and completely automatic method, based on frontal and profile images of the patient's face, to predict the difficulty of intubation. We also provide a new database of three dimensional (3D) facial scans and present the initial steps towards a complete 3D model of the face suitable for facial morphometry applications, which include difficult tracheal intubation prediction. In order to develop and test our proposed method, we collected a large database of multimodal recordings of over 2700 patients undergoing general anesthesia. In the first part of this thesis, using two dimensional (2D) facial image analysis methods, we automatically extract morphological and appearance-based features from these images. These are used to train a classifier, which learns to discriminate between patients as being easy or difficult to intubate. We validate our approach on two different scenarios, one of them being close to a real-world clinical scenario, using 966 patients, and demonstrate that the proposed method achieves performance comparable to medical diagnosis-based predictions by experienced anesthesiologists. In the second part of this thesis, we focus on the development of a new 3D statistical model of the face to overcome some of the limitations of 2D methods. We first present EPFL3DFace, a new database of 3D facial expression scans, containing 120 subjects, performing 35 different facial expressions. Then, we develop a nonrigid alignment method to register the scans and allow for statistical analysis. Our proposed method is based on spectral geometry processing and makes use of an implicit representation of the scans in order to be robust to noise or holes in the surfaces. It presents the significant advantage of reducing the number of free parameters to optimize for in the alignment process by two orders of magnitude. We apply our proposed method on the data collected and discuss qualitative results. At its current level of performance, our fully automatic method to predict difficult intubation already has the potential to reduce the cost, and increase the availability of such predictions, by not relying on qualified anesthesiologists with years of medical training. Further data collection, in order to increase the number of patients who are difficult to intubate, as well as extracting morphological features from a 3D representation of the face are key elements to further improve the performance

Text Similarity Between Concepts Extracted from Source Code and Documentation

Context: Constant evolution in software systems often results in its documentation losing sync with the content of the source code. The traceability research field has often helped in the past with the aim to recover links between code and documentation, when the two fell out of sync. Objective: The aim of this paper is to compare the concepts contained within the source code of a system with those extracted from its documentation, in order to detect how similar these two sets are. If vastly different, the difference between the two sets might indicate a considerable ageing of the documentation, and a need to update it. Methods: In this paper we reduce the source code of 50 software systems to a set of key terms, each containing the concepts of one of the systems sampled. At the same time, we reduce the documentation of each system to another set of key terms. We then use four different approaches for set comparison to detect how the sets are similar. Results: Using the well known Jaccard index as the benchmark for the comparisons, we have discovered that the cosine distance has excellent comparative powers, and depending on the pre-training of the machine learning model. In particular, the SpaCy and the FastText embeddings offer up to 80% and 90% similarity scores. Conclusion: For most of the sampled systems, the source code and the documentation tend to contain very similar concepts. Given the accuracy for one pre-trained model (e.g., FastText), it becomes also evident that a few systems show a measurable drift between the concepts contained in the documentation and in the source code.</p

Calculating the curvature shape characteristics of the human body from 3D scanner data.

In the recent years, there have been significant advances in the development and manufacturing of 3D scanners capable of capturing detailed (external) images of whole human bodies. Such hardware offers the opportunity to collect information that could be used to describe, interpret and analyse the shape of the human body for a variety of applications where shape information plays a vital role (e.g. apparel sizing and customisation; medical research in fields such as nutrition, obesity/anorexia and perceptive psychology; ergonomics for vehicle and furniture design). However, the representations delivered by such hardware typically consist of unstructured or partially structured point clouds, whereas it would be desirable to have models that allow shape-related information to be more immediately accessible. This thesis describes a method of extracting the differential geometry properties of the body surface from unorganized point cloud datasets. In effect, this is a way of constructing curvature maps that allows the detection on the surface of features that are deformable (such as ridges) rather than reformable under certain transformations. Such features could subsequently be used to interpret the topology of a human body and to enable classification according to its shape, rather than its size (as is currently the standard practice for many of the applications concemed). The background, motivation and significance of this research are presented in chapter one. Chapter two is a literature review describing the previous and current attempts to model 3D objects in general and human bodies in particular, as well as the mathematical and technical issues associated with the modelling. Chapter three presents an overview of: the methodology employed throughout the research; the assumptions regarding the data to be processed; and the strategy for evaluating the results for each stage of the methodology. Chapter four describes an algorithm (and some variations) for approximating the local surface geometry around a given point of the input data set by means of a least-squares minimization. The output of such an algorithm is a surface patch described in an analytic (implicit) form. This is necessary for the next step described below. The case is made for using implicit surfaces rather than more popular 3D surface representations such as parametric forms or height functions. Chapter five describes the processing needed for calculating curvature-related characteristics for each point of the input surface. This utilises the implicit surface patches generated by the algorithm described in the previous chapter, and enables the construction of a "curvature map" of the original surface, which incorporates rich information such as the principal curvatures, shape indices and curvature directions. Chapter six describes a family of algorithms for calculating features such as ridges and umbilic points on the surface from the curvature map, in a manner that bypasses the problem of separating a vector field (i.e. the principal curvature directions) across the entire surface of an object. An alternative approach, using the focal surface information, is also considered briefly in comparison. The concluding chapter summarises the results from all steps of the processing and evaluates them in relation to the requirements set in chapter one. Directions for further research are also proposed

Proceedings of the Seventh Congress of the European Society for Research in Mathematics Education

International audienceThis volume contains the Proceedings of the Seventh Congress of the European Society for Research in Mathematics Education (ERME), which took place 9-13 February 2011, at Rzeszñw in Poland