Cardiac ultrasound simulation for autonomous ultrasound navigation

Ultrasound is well-established as an imaging modality for diagnostic and interventional purposes. However, the image quality varies with operator skills as acquiring and interpreting ultrasound images requires extensive training due to the imaging artefacts, the range of acquisition parameters and the variability of patient anatomies. Automating the image acquisition task could improve acquisition reproducibility and quality but training such an algorithm requires large amounts of navigation data, not saved in routine examinations. Thus, we propose a method to generate large amounts of ultrasound images from other modalities and from arbitrary positions, such that this pipeline can later be used by learning algorithms for navigation. We present a novel simulation pipeline which uses segmentations from other modalities, an optimized volumetric data representation and GPU-accelerated Monte Carlo path tracing to generate view-dependent and patient-specific ultrasound images. We extensively validate the correctness of our pipeline with a phantom experiment, where structures' sizes, contrast and speckle noise properties are assessed. Furthermore, we demonstrate its usability to train neural networks for navigation in an echocardiography view classification experiment by generating synthetic images from more than 1000 patients. Networks pre-trained with our simulations achieve significantly superior performance in settings where large real datasets are not available, especially for under-represented classes. The proposed approach allows for fast and accurate patient-specific ultrasound image generation, and its usability for training networks for navigation-related tasks is demonstrated.Comment: 24 pages, 10 figures, 5 table

Computational Light Transport for Forward and Inverse Problems.

El transporte de luz computacional comprende todas las técnicas usadas para calcular el flujo de luz en una escena virtual. Su uso es ubicuo en distintas aplicaciones, desde entretenimiento y publicidad, hasta diseño de producto, ingeniería y arquitectura, incluyendo el generar datos validados para técnicas basadas en imagen por ordenador. Sin embargo, simular el transporte de luz de manera precisa es un proceso costoso. Como consecuencia, hay que establecer un balance entre la fidelidad de la simulación física y su coste computacional. Por ejemplo, es común asumir óptica geométrica o una velocidad de propagación de la luz infinita, o simplificar los modelos de reflectancia ignorando ciertos fenómenos. En esta tesis introducimos varias contribuciones a la simulación del transporte de luz, dirigidas tanto a mejorar la eficiencia del cálculo de la misma, como a expandir el rango de sus aplicaciones prácticas. Prestamos especial atención a remover la asunción de una velocidad de propagación infinita, generalizando el transporte de luz a su estado transitorio. Respecto a la mejora de eficiencia, presentamos un método para calcular el flujo de luz que incide directamente desde luminarias en un sistema de generación de imágenes por Monte Carlo, reduciendo significativamente la variancia de las imágenes resultantes usando el mismo tiempo de ejecución. Asimismo, introducimos una técnica basada en estimación de densidad en el estado transitorio, que permite reusar mejor las muestras temporales en un medio parcipativo. En el dominio de las aplicaciones, también introducimos dos nuevos usos del transporte de luz: Un modelo para simular un tipo especial de pigmentos gonicromáticos que exhiben apariencia perlescente, con el objetivo de proveer una forma de edición intuitiva para manufactura, y una técnica de imagen sin línea de visión directa usando información del tiempo de vuelo de la luz, construida sobre un modelo de propagación de la luz basado en ondas.<br /

Simulation-based Planning of Machine Vision Inspection Systems with an Application to Laser Triangulation

Nowadays, vision systems play a central role in industrial inspection. The experts typically choose the configuration of measurements in such systems empirically. For complex inspections, however, automatic inspection planning is essential. This book proposes a simulation-based approach towards inspection planning by contributing to all components of this problem: simulation, evaluation, and optimization. As an application, inspection of a complex cylinder head by laser triangulation is studied

Visual Prototyping of Cloth

Realistic visualization of cloth has many applications in computer graphics. An ongoing research problem is how to best represent and capture appearance models of cloth, especially when considering computer aided design of cloth. Previous methods can be used to produce highly realistic images, however, possibilities for cloth-editing are either restricted or require the measurement of large material databases to capture all variations of cloth samples. We propose a pipeline for designing the appearance of cloth directly based on those elements that can be changed within the production process. These are optical properties of fibers, geometrical properties of yarns and compositional elements such as weave patterns. We introduce a geometric yarn model, integrating state-of-the-art textile research. We further present an approach to reverse engineer cloth and estimate parameters for a procedural cloth model from single images. This includes the automatic estimation of yarn paths, yarn widths, their variation and a weave pattern. We demonstrate that we are able to match the appearance of original cloth samples in an input photograph for several examples. Parameters of our model are fully editable, enabling intuitive appearance design. Unfortunately, such explicit fiber-based models can only be used to render small cloth samples, due to large storage requirements. Recently, bidirectional texture functions (BTFs) have become popular for efficient photo-realistic rendering of materials. We present a rendering approach combining the strength of a procedural model of micro-geometry with the efficiency of BTFs. We propose a method for the computation of synthetic BTFs using Monte Carlo path tracing of micro-geometry. We observe that BTFs usually consist of many similar apparent bidirectional reflectance distribution functions (ABRDFs). By exploiting structural self-similarity, we can reduce rendering times by one order of magnitude. This is done in a process we call non-local image reconstruction, which has been inspired by non-local means filtering. Our results indicate that synthesizing BTFs is highly practical and may currently only take a few minutes for small BTFs. We finally propose a novel and general approach to physically accurate rendering of large cloth samples. By using a statistical volumetric model, approximating the distribution of yarn fibers, a prohibitively costly, explicit geometric representation is avoided. As a result, accurate rendering of even large pieces of fabrics becomes practical without sacrificing much generality compared to fiber-based techniques

Real-time statistical simulation of dynamic laser speckle

Lasers have several applications in the industry, such as cutting, engraving, and drilling. A specific use of lasers is taking distance measurements, by shining beams of light at objects and observing the hit points with an infrared camera. However, the depth measurements are inevitably inaccurate. This is mainly due to the manufacturing and design errors in beam splitters and dynamic speckle. The goal of this thesis is not to reduce the contribution of these effects, but to introduce them into a computer simulation, to make the virtual model as close as possible to reality. Studying the works of J. W. Goodman, Donald D. Duncan, and others in the field of Fourier Optics gave a solid theoretical foundation of the beam splitter and dynamic speckle. To tailor the general theory to this specific case, various physical experiments were carried out. Based on the theory and the experiment results, a way to extend an already existing physically based rendering engine was proposed. In conclusion, this extension produces similar results in the simulation to what is observable in real life. This is achieved with a small computational overhead on a modern graphics processor. Due to these properties, the technique can be used for more robust testing of depth estimation and reconstruction algorithms. Moreover, it also raises the quality of machine learning data that can be collected in large volumes from a computer simulation of this setup, leading to better downstream performance