Fast Recompilation of Object Oriented Modules

Once a program file is modified, the recompilation time should be minimized, without sacrificing execution speed or high level object oriented features. The recompilation time is often a problem for the large graphical interactive distributed applications tackled by modern OO languages. A compilation server and fast code generator were developed and integrated with the SRC Modula-3 compiler and Linux ELF dynamic linker. The resulting compilation and recompilation speedups are impressive. The impact of different language features, processor speed, and application size are discussed

SHARE with CHARM

SHARE with CHARM program (SHAREv3) implements the statistical hadronization model description of particle production in relativistic heavy-ion collisions. Given a set of statistical parameters, SHAREv3 program evaluates yields and therefore also ratios, and furthermore, statistical particle abundance fluctuations. The physical bulk properties of the particle source is evaluated based on all hadrons produced, including the fitted yields. The bulk properties can be prescribed as a fit input complementing and/or replacing the statistical parameters. The modifications and improvements in the SHARE suite of programs are oriented towards recent and forthcoming LHC hadron production results including charm hadrons. This SHAREv3 release incorporates all features seen previously in SHAREv1.x and v2.x and, beyond, we include a complete treatment of charm hadrons and their decays, which further cascade and feed lighter hadron yields. This article is a complete and self-contained manual explaining and introducing both the conventional and the extended capabilities of SHARE with CHARM. We complement the particle list derived from the Particle Data Group tabulation composed of up, down, strange $u,d,s$ quarks (including resonances) with hadrons containing charm $c,\bar c$ quarks. We provide a table of the charm hadron decays including partial widths. The branching ratios of each charm hadron decays add to unity, which is achieved by including some charm hadron decay channels based on theoretical consideration in the absence of direct experimental information. A very successful interpretation of all available LHC results has been already obtained using this program.Comment: 41 pages, 5 figures, 3 tables. Associated program available at http://www.physics.arizona.edu/~gtshare/SHARE/share.html (Computer Physics Communications in press

Peer-to-Peer Grids

We describe Peer-to-Peer Grids built around Integration of technologies from the peer-to-peer and Grid fields. We focus on the role of Web services linked by a powerful event service using uniform XML interfaces and application level routing. We describe how a rich synchronous and asynchronous collaboration environment can support virtual communities built on top of such infrastructure. Universal access mechanisms are discussed

Study of mineral dissolution by kinetic Monte Carlo simulations.

172 p.El método Monte Carlo Cinético es el complemento perfecto de las simulaciones atómicas debido a su poder para llevar sus resultados a escalas espaciales y temporales comparables con los experimentos. Juntos contribuyen a predecir y entender las propiedades de sistemas reales y extender el conocimiento más allá de los límites experimentales. En esta tesis hemos aplicado el Monte Carlo Cinético junto con un novedoso modelo para estudiar la disolución de los minerales, lo que nos ha permitido responder a algunas preguntas sin resolver detrás de los mecanismos de disolución a escala atómica. Además, la concordancia de nuestro modelo con los resultados experimentales nos ha animado a desarrollar KIMERA, un programa en C++ capaz de estudiar la disolución de una multitud de minerales con resolución atómica.Tecnali

Study of mineral dissolution by kinetic Monte Carlo simulations.

172 p.El método Monte Carlo Cinético es el complemento perfecto de las simulaciones atómicas debido a su poder para llevar sus resultados a escalas espaciales y temporales comparables con los experimentos. Juntos contribuyen a predecir y entender las propiedades de sistemas reales y extender el conocimiento más allá de los límites experimentales. En esta tesis hemos aplicado el Monte Carlo Cinético junto con un novedoso modelo para estudiar la disolución de los minerales, lo que nos ha permitido responder a algunas preguntas sin resolver detrás de los mecanismos de disolución a escala atómica. Además, la concordancia de nuestro modelo con los resultados experimentales nos ha animado a desarrollar KIMERA, un programa en C++ capaz de estudiar la disolución de una multitud de minerales con resolución atómica.Tecnali

On the puzzling feature of the silence of precursory electromagnetic emissions

It has been suggested that fracture-induced MHz-kHz electromagnetic (EM) emissions, which emerge from a few days up to a few hours before the main seismic shock occurrence permit a real-time monitoring of the damage process during the last stages of earthquake preparation, as it happens at the laboratory scale. Despite fairly abundant evidence, EM precursors have not been adequately accepted as credible physical phenomena. These negative views are enhanced by the fact that certain 'puzzling features' are repetitively observed in candidate fracture-induced pre-seismic EM emissions. More precisely, EM silence in all frequency bands appears before the main seismic shock occurrence, as well as during the aftershock period. Actually, the view that 'acceptance of 'precursive' EM signals without convincing co-seismic signals should not be expected' seems to be reasonable. In this work we focus on this point. We examine whether the aforementioned features of EM silence are really puzzling ones or, instead, reflect well-documented characteristic features of the fracture process, in terms of: universal structural patterns of the fracture process, recent laboratory experiments, numerical and theoretical studies of fracture dynamics, critical phenomena, percolation theory, and micromechanics of granular materials. Our analysis shows that these features should not be considered puzzling.Comment: arXiv admin note: text overlap with arXiv:cond-mat/0603542 by other author

Fractals in the Nervous System: conceptual Implications for Theoretical Neuroscience

This essay is presented with two principal objectives in mind: first, to document the prevalence of fractals at all levels of the nervous system, giving credence to the notion of their functional relevance; and second, to draw attention to the as yet still unresolved issues of the detailed relationships among power law scaling, self-similarity, and self-organized criticality. As regards criticality, I will document that it has become a pivotal reference point in Neurodynamics. Furthermore, I will emphasize the not yet fully appreciated significance of allometric control processes. For dynamic fractals, I will assemble reasons for attributing to them the capacity to adapt task execution to contextual changes across a range of scales. The final Section consists of general reflections on the implications of the reviewed data, and identifies what appear to be issues of fundamental importance for future research in the rapidly evolving topic of this review

Visualization of mucosal field in HPV positive and negative oropharyngeal squamous cell carcinomas: combined genomic and radiology based 3D model

The aim of this study was to visualize the tumor propagation and surrounding mucosal field in radiography-based 3D model for advanced stage HNSCC and combine it with HPV genotyping and miRNA expression characterization of the visualized area. 25 patients with T1-3 clinical stage HNSCC were enrolled in mapping biopsy sampling. Biopsy samples were evaluated for HPV positivity and miR-21-5p, miR-143, miR-155, miR-221-5p expression in Digital Droplet PCR system. Significant miRNA expression differences of HPV positive tumor tissue biopsies were found for miR-21-5p, miR-143 and miR-221-5p compared to the HPV negative tumor biopsy series. Peritumoral mucosa showed patchy pattern alterations of miR-21-5p and miR-155 in HPV positive cases, while gradual change of miR-21-5p and miR-221-5p was seen in HPV negative tumors. In our study we found differences of the miRNA expression patterns among the HPV positive and negative tumorous tissues as well as the surrounding mucosal fields. The CT based 3D models of the cancer field and surrounding mucosal surface can be utilized to improve proper preoperative planning. Complex evaluation of HNSCC tissue organization field can elucidate the clinical and molecular differentiation of HPV positive and negative cases, and enhance effective organ saving therapeutic strategies