A Hybrid Feature Extraction Method With Regularized Extreme Learning Machine for Brain Tumor Classification

Brain cancer classification is an important step that depends on the physician's knowledge and experience. An automated tumor classification system is very essential to support radiologists and physicians to identify brain tumors. However, the accuracy of current systems needs to be improved for suitable treatments. In this paper, we propose a hybrid feature extraction method with a regularized extreme learning machine (RELM) for developing an accurate brain tumor classification approach. The approach starts by preprocessing the brain images by using a min–max normalization rule to enhance the contrast of brain edges and regions. Then, the brain tumor features are extracted based on a hybrid method of feature extraction. Finally, a RELM is used for classifying the type of brain tumor. To evaluate and compare the proposed approach, a set of experiments is conducted on a new public dataset of brain images. The experimental results proved that the approach is more effective compared with the existing state-of-the-art approaches, and the performance in terms of classification accuracy improved from 91.51% to 94.233% for the experiment of the random holdout technique

Three Step Authentication of Brain Tumour Segmentation Using Hybrid Active Contour Model and Discrete Wavelet Transform

An innovative imaging research is expected in the medical field due to the challenges and inaccuracies in diagnosing the life-threatened harmful tumours. Brain tumor diagnosis is one of the most difficult areas of study in diagnostic imaging, with the maximum fine for a small glitch given the patients survival rate. Conventionally, biopsy method is used to identify the tumour tissues from the brain's soft tissues by the medical researchers (or) practitioners and it is unproductive due to: (i) it requires more time, and (ii) it may have errors. This paper presents the three-stage authentication-based hybrid brain tumour segmentation process and it makes the detection more accrual. Primarily, tumour area is segmented from a magnetic resonance image and after that when comparing a differentiated segment of an image to the actual image, an improved active contour model is employed to achieve a good match. In addition, discrete wavelet transform is used for the features extraction which leads to improve the accuracy and robustness in the tumour diagnosis. Finally, RELM classifier is used for precise classification of brain tumours. The most effective section of our method is checking the status of the tumour through finding the tumour region. The results are evaluated through new dataset, and it demonstrates that the suggested approach is more efficient than the alternatives as well as provides 96.25% accuracy

A Novel Technique for Brain Tumor Detection and Classification using T1-Weighted MR Image

Brain tumors are particularly perilous because they form when cells in the brain multiply uncontrollably within the skull. Therefore, a fast and accurate method of diagnosing tumors is crucial for the patient’s health. This study proposes a method for evaluating brain cancer images. The phases of implementation for the proposed work are as follows: In the first phase, we compiled a set of specialized feature vector descriptions for advanced classification tasks by employing both deep learning (DL) and conventional feature extraction techniques. In the second phase, we employ a proposed convolutional neural network (CNN) approach and a traditional subset of features from a genetic algorithm (GA) to select our deep features. The third phase involves using the fusion method to merge the prioritized features. Finally, determine whether the brain image is normal or abnormal. The results showed that the proposed method successfully classified objects accurately and revealed their robustness across different ages and acquisition protocols. According to the results, the classification accuracy of the support vector machines (SVM) classifier has significantly improved by combining conventional features and deep learning features (DLF), achieving an accuracy of up to 86.50% using the T1 weighted brain MR image

Machine Learning and Integrative Analysis of Biomedical Big Data.

Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues

Deep learning based Brain Tumour Classification based on Recursive Sigmoid Neural Network based on Multi-Scale Neural Segmentation

Brain tumours are malignant tissues in which cells replicate rapidly and indefinitely, and tumours grow out of control. Deep learning has the potential to overcome challenges associated with brain tumour diagnosis and intervention. It is well known that segmentation methods can be used to remove abnormal tumour areas in the brain. It is one of the advanced technology classification and detection tools. Can effectively achieve early diagnosis of the disease or brain tumours through reliable and advanced neural network classification algorithms. Previous algorithm has some drawbacks, an automatic and reliable method for segmentation is needed. However, the large spatial and structural heterogeneity between brain tumors makes automated segmentation a challenging problem. Image tumors have irregular shapes and are spatially located in any part of the brain, making their segmentation is inaccurate for clinical purposes a challenging task. In this work, propose a method Recursive SigmoidNeural Network based on Multi-scale Neural Segmentation (RSN2-MSNS) for image proper segmentation. Initially collets the image dataset from standard repository for brain tumour classification.  Next, pre-processing method that targets only a small part of an image rather than the entire image. This approach reduces computational time and overcomes the over complication. Second stage, segmenting the images based on the Enhanced Deep Clustering U-net (EDCU-net) for estimating the boundary points in the brain tumour images. This method can successfully colour histogram values are evaluating segment complex images that contain both textured and non-textured regions. Third stage, Feature extraction for extracts the features from segmenting images using Convolution Deep Feature Spectral Similarity (CDFS2) scaled the values from images extracting the relevant weights based on its threshold limits. Then selecting the features from extracting stage, this selection is based on the relational weights. And finally classified the features based on the Recursive Sigmoid Neural Network based on Multi-scale Neural Segmentation (RSN2-MSNS) for evaluating the proposed brain tumour classification model consists of 1500 trainable images and the proposed method achieves 97.0% accuracy. The sensitivity, specificity, detection accuracy and F1 measures were 96.4%, 952%, and 95.9%, respectively

A Novel Convolutional Neural Network Based on Combined Features from Different Transformations for Brain Tumor Diagnosis

Brain tumors are a leading cause of death worldwide. With the advancements in medicine and deep learning technologies, the dependency on manual classification-based diagnosis drives down owing to their inaccurate diagnosis and prognosis. Accordingly, the proposed model provides an accurate multi-class classification model for brain tumor using the convolution neural network (CNN) as a backbone. Our novel model is based on concatenating the extracted features from the proposed three branches of CNN, where each branch is fed by the output of different transform domains of the original magnetic resonance image (MRI). These transformations include Discrete Cosine Transform (DCT), Discrete Wavelet Transform (DWT), and the time-domain of the original image. Then, the CNN is employed followed by a concatenation layer, flatten laver, and dense layer, before using the SoftMax layer. The proposed model was applied to the Figshare dataset of brain tumor which consists of three classes pituitary, glioma, and meningioma. The results proved the advantage of the proposed system which achieved a high mean performance over 5-fold cross-validation with 98.89% accuracy, 98.78% F1-score, 98.74% precision, 98.82% recall, and 99.44% specificity. The comparative study with well-known models, as well as the pre-trained CNN models, established the potential of the proposed model. This novel approach has the potential to significantly improve brain tumor classification accuracy. It enables a more comprehensive and objective analysis of brain tumors, leading to improved treatment decisions and better patient care

A Novel Convolutional Neural Network Based on Combined Features from Different Transformations for Brain Tumor Diagnosis

Brain tumors are a leading cause of death worldwide. With the advancements in medicine and deep learning technologies, the dependency on manual classification-based diagnosis drives down owing to their inaccurate diagnosis and prognosis. Accordingly, the proposed model provides an accurate multi-class classification model for brain tumor using the convolution neural network (CNN) as a backbone. Our novel model is based on concatenating the extracted features from the proposed three branches of CNN, where each branch is fed by the output of different transform domains of the original magnetic resonance image (MRI). These transformations include Discrete Cosine Transform (DCT), Discrete Wavelet Transform (DWT), and the time-domain of the original image. Then, the CNN is employed followed by a concatenation layer, flatten laver, and dense layer, before using the SoftMax layer. The proposed model was applied to the Figshare dataset of brain tumor which consists of three classes pituitary, glioma, and meningioma. The results proved the advantage of the proposed system which achieved a high mean performance over 5-fold cross-validation with 98.89% accuracy, 98.78% F1-score, 98.74% precision, 98.82% recall, and 99.44% specificity. The comparative study with well-known models, as well as the pre-trained CNN models, established the potential of the proposed model. This novel approach has the potential to significantly improve brain tumor classification accuracy. It enables a more comprehensive and objective analysis of brain tumors, leading to improved treatment decisions and better patient care