Impact of obstructive sleep apnoea and experiences of using positive airway pressure

The aim of this thesis was to explore the impact of the common sleep-related breathing disorder, obstructive sleep apnoea (OSA); specifically for people with a bipolar disorder (BD) diagnosis but also the wider experience of the first-line treatment for OSA, positive airway pressure (PAP). Chapter 1 is a systematic literature review and thematic synthesis of experiences using PAP to treat OSA. Twenty-five papers were reviewed and included in the thematic synthesis. The quality of each paper was appraised and considered in relation to contribution to the resultant analytical themes. The metasynthesis gave voice to user experiences of PAP and revealed barriers to PAP use at a healthcare service level. The findings highlight the need for a biopsychosocial approach and long-term person-centred support to enhance PAP use. Chapter 2 is a primary empirical research paper on an investigation as to whether people with suspected-OSA and a BD diagnosis experience more sleep and affect instability when “inter-episode” compared to people with a BD diagnosis alone. Ecological momentary assessment was utilised. Eighteen participants (twelve with suspected-OSA) wore an acitgraph for two weeks whilst completing an affect questionnaire twice daily. Measures of instability were calculated using the mean squared successive difference and probability of acute change indices. The groups were not found to significantly differ other than reduced sleep efficiency in the suspected-OSA group. However, only 48% of the intended sample was successfully recruited due to the COVID-19 pandemic. Important avenues for further research are highlighted. Chapter 3 is a critical appraisal of the thesis. Salient issues relevant to future research and clinical practice are discussed, in addition to the under recognised clinical issue of sleep which inspired this thesis

Abstracts from the 50th European Society of Human Genetics Conference: Posters

International audienc

Textbook on Scar Management

This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners ; Comprehensive reference covering the complete field of wounds and scar management: semiology, classifications and scoring Highly educational contents for trainees as well as professionals in plastic surgery, dermatology, surgery, oncology as well as nurses and general practitioners Fast access to information through key points, take home messages, highlights, and a wealth of clinical cases Book didactic contents enhanced by supplementary material and video

Textbook on Scar Management

This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners ; Comprehensive reference covering the complete field of wounds and scar management: semiology, classifications and scoring Highly educational contents for trainees as well as professionals in plastic surgery, dermatology, surgery, oncology as well as nurses and general practitioners Fast access to information through key points, take home messages, highlights, and a wealth of clinical cases Book didactic contents enhanced by supplementary material and video

Applications and Experiences of Quality Control

The rich palette of topics set out in this book provides a sufficiently broad overview of the developments in the field of quality control. By providing detailed information on various aspects of quality control, this book can serve as a basis for starting interdisciplinary cooperation, which has increasingly become an integral part of scientific and applied research

Aerospace medicine and biology, an annotated bibliography. volume xi- 1962-1963 literature

Aerospace medicine and biology - annotated bibliography for 1962 and 196

A descriptive model for determining optimal human performance in systems. Volume 3 - An approach for determining the optimal role of man and allocation of functions in an aerospace system

Optimal role of man in space, allocation of men and machines in aerospace systems, and descriptive model for determining optimal human performanc