Diffeomorphic density registration

In this book chapter we study the Riemannian Geometry of the density registration problem: Given two densities (not necessarily probability densities) defined on a smooth finite dimensional manifold find a diffeomorphism which transforms one to the other. This problem is motivated by the medical imaging application of tracking organ motion due to respiration in Thoracic CT imaging where the fundamental physical property of conservation of mass naturally leads to modeling CT attenuation as a density. We will study the intimate link between the Riemannian metrics on the space of diffeomorphisms and those on the space of densities. We finally develop novel computationally efficient algorithms and demonstrate there applicability for registering RCCT thoracic imaging.Comment: 23 pages, 6 Figures, Chapter for a Book on Medical Image Analysi

Geodesics on the manifold of multivariate generalized Gaussian distributions with an application to multicomponent texture discrimination

We consider the Rao geodesic distance (GD) based on the Fisher information as a similarity measure on the manifold of zero-mean multivariate generalized Gaussian distributions (MGGD). The MGGD is shown to be an adequate model for the heavy-tailed wavelet statistics in multicomponent images, such as color or multispectral images. We discuss the estimation of MGGD parameters using various methods. We apply the GD between MGGDs to color texture discrimination in several classification experiments, taking into account the correlation structure between the spectral bands in the wavelet domain. We compare the performance, both in terms of texture discrimination capability and computational load, of the GD and the Kullback-Leibler divergence (KLD). Likewise, both uni- and multivariate generalized Gaussian models are evaluated, characterized by a fixed or a variable shape parameter. The modeling of the interband correlation significantly improves classification efficiency, while the GD is shown to consistently outperform the KLD as a similarity measure

On the Limiting Behaviour of the Fundamental Geodesics of Information Geometry

The Information Geometry of extended exponential families has received much recent attention in a variety of important applications, notably categorical data analysis, graphical modelling and, more specifically, log-linear modelling. The essential geometry here comes from the closure of an exponential family in a high-dimensional simplex. In parallel, there has been a great deal of interest in the purely Fisher Riemannian structure of (extended) exponential families, most especially in the Markov chain Monte Carlo literature. These parallel developments raise challenges, addressed here, at a variety of levels: both theoretical and practical—relatedly, conceptual and methodological. Centrally to this endeavour, this paper makes explicit the underlying geometry of these two areas via an analysis of the limiting behaviour of the fundamental geodesics of Information Geometry, these being Amari’s (+1) and (0)-geodesics, respectively. Overall, a substantially more complete account of the Information Geometry of extended exponential families is provided than has hitherto been the case. We illustrate the importance and benefits of this novel formulation through applications

Diffeomorphic density matching by optimal information transport

We address the following problem: given two smooth densities on a manifold, find an optimal diffeomorphism that transforms one density into the other. Our framework builds on connections between the Fisher-Rao information metric on the space of probability densities and right-invariant metrics on the infinite-dimensional manifold of diffeomorphisms. This optimal information transport, and modifications thereof, allows us to construct numerical algorithms for density matching. The algorithms are inherently more efficient than those based on optimal mass transport or diffeomorphic registration. Our methods have applications in medical image registration, texture mapping, image morphing, non-uniform random sampling, and mesh adaptivity. Some of these applications are illustrated in examples.Comment: 35 page

Weighted Diffeomorphic Density Matching with Applications to Thoracic Image Registration

In this article we study the problem of thoracic image registration, in particular the estimation of complex anatomical deformations associated with the breathing cycle. Using the intimate link between the Riemannian geometry of the space of diffeomorphisms and the space of densities, we develop an image registration framework that incorporates both the fundamental law of conservation of mass as well as spatially varying tissue compressibility properties. By exploiting the geometrical structure, the resulting algorithm is computationally efficient, yet widely general.Comment: Accepted in Proceedings of the 5th MICCAI workshop on Mathematical Foundations of Computational Anatomy, Munich, Germany, 2015 (http://www-sop.inria.fr/asclepios/events/MFCA15/

Discussion of "Geodesic Monte Carlo on Embedded Manifolds"

Contributed discussion and rejoinder to "Geodesic Monte Carlo on Embedded Manifolds" (arXiv:1301.6064)Comment: Discussion of arXiv:1301.6064. To appear in the Scandinavian Journal of Statistics. 18 page