Graph analysis of functional brain networks: practical issues in translational neuroscience

The brain can be regarded as a network: a connected system where nodes, or units, represent different specialized regions and links, or connections, represent communication pathways. From a functional perspective communication is coded by temporal dependence between the activities of different brain areas. In the last decade, the abstract representation of the brain as a graph has allowed to visualize functional brain networks and describe their non-trivial topological properties in a compact and objective way. Nowadays, the use of graph analysis in translational neuroscience has become essential to quantify brain dysfunctions in terms of aberrant reconfiguration of functional brain networks. Despite its evident impact, graph analysis of functional brain networks is not a simple toolbox that can be blindly applied to brain signals. On the one hand, it requires a know-how of all the methodological steps of the processing pipeline that manipulates the input brain signals and extract the functional network properties. On the other hand, a knowledge of the neural phenomenon under study is required to perform physiological-relevant analysis. The aim of this review is to provide practical indications to make sense of brain network analysis and contrast counterproductive attitudes

Spectral analysis of stationary random bivariate signals

A novel approach towards the spectral analysis of stationary random bivariate signals is proposed. Using the Quaternion Fourier Transform, we introduce a quaternion-valued spectral representation of random bivariate signals seen as complex-valued sequences. This makes possible the definition of a scalar quaternion-valued spectral density for bivariate signals. This spectral density can be meaningfully interpreted in terms of frequency-dependent polarization attributes. A natural decomposition of any random bivariate signal in terms of unpolarized and polarized components is introduced. Nonparametric spectral density estimation is investigated, and we introduce the polarization periodogram of a random bivariate signal. Numerical experiments support our theoretical analysis, illustrating the relevance of the approach on synthetic data.Comment: 11 pages, 3 figure

Data-driven multivariate and multiscale methods for brain computer interface

This thesis focuses on the development of data-driven multivariate and multiscale methods for brain computer interface (BCI) systems. The electroencephalogram (EEG), the most convenient means to measure neurophysiological activity due to its noninvasive nature, is mainly considered. The nonlinearity and nonstationarity inherent in EEG and its multichannel recording nature require a new set of data-driven multivariate techniques to estimate more accurately features for enhanced BCI operation. Also, a long term goal is to enable an alternative EEG recording strategy for achieving long-term and portable monitoring. Empirical mode decomposition (EMD) and local mean decomposition (LMD), fully data-driven adaptive tools, are considered to decompose the nonlinear and nonstationary EEG signal into a set of components which are highly localised in time and frequency. It is shown that the complex and multivariate extensions of EMD, which can exploit common oscillatory modes within multivariate (multichannel) data, can be used to accurately estimate and compare the amplitude and phase information among multiple sources, a key for the feature extraction of BCI system. A complex extension of local mean decomposition is also introduced and its operation is illustrated on two channel neuronal spike streams. Common spatial pattern (CSP), a standard feature extraction technique for BCI application, is also extended to complex domain using the augmented complex statistics. Depending on the circularity/noncircularity of a complex signal, one of the complex CSP algorithms can be chosen to produce the best classification performance between two different EEG classes. Using these complex and multivariate algorithms, two cognitive brain studies are investigated for more natural and intuitive design of advanced BCI systems. Firstly, a Yarbus-style auditory selective attention experiment is introduced to measure the user attention to a sound source among a mixture of sound stimuli, which is aimed at improving the usefulness of hearing instruments such as hearing aid. Secondly, emotion experiments elicited by taste and taste recall are examined to determine the pleasure and displeasure of a food for the implementation of affective computing. The separation between two emotional responses is examined using real and complex-valued common spatial pattern methods. Finally, we introduce a novel approach to brain monitoring based on EEG recordings from within the ear canal, embedded on a custom made hearing aid earplug. The new platform promises the possibility of both short- and long-term continuous use for standard brain monitoring and interfacing applications

AoA-aware Probabilistic Indoor Location Fingerprinting using Channel State Information

With expeditious development of wireless communications, location fingerprinting (LF) has nurtured considerable indoor location based services (ILBSs) in the field of Internet of Things (IoT). For most pattern-matching based LF solutions, previous works either appeal to the simple received signal strength (RSS), which suffers from dramatic performance degradation due to sophisticated environmental dynamics, or rely on the fine-grained physical layer channel state information (CSI), whose intricate structure leads to an increased computational complexity. Meanwhile, the harsh indoor environment can also breed similar radio signatures among certain predefined reference points (RPs), which may be randomly distributed in the area of interest, thus mightily tampering the location mapping accuracy. To work out these dilemmas, during the offline site survey, we first adopt autoregressive (AR) modeling entropy of CSI amplitude as location fingerprint, which shares the structural simplicity of RSS while reserving the most location-specific statistical channel information. Moreover, an additional angle of arrival (AoA) fingerprint can be accurately retrieved from CSI phase through an enhanced subspace based algorithm, which serves to further eliminate the error-prone RP candidates. In the online phase, by exploiting both CSI amplitude and phase information, a novel bivariate kernel regression scheme is proposed to precisely infer the target's location. Results from extensive indoor experiments validate the superior localization performance of our proposed system over previous approaches

Widely Linear State Space Filtering of Improper Complex Signals

Complex signals are the backbone of many modern applications, such as power systems, communication systems, biomedical sciences and military technologies. However, standard complex valued signal processing approaches are suited to only a subset of complex signals known as proper, and are inadequate of the generality of complex signals, as they do not fully exploit the available information. This is mainly due to the inherent blindness of the algorithms to the complete second order statistics of the signals, or due to under-modelling of the underlying system. The aim of this thesis is to provide enhanced complex valued, state space based, signal processing solutions for the generality of complex signals and systems. This is achieved based on the recent advances in the so called augmented complex statistics and widely linear modelling, which have brought to light the limitations of conventional statistical complex signal processing approaches. Exploiting these developments, we propose a class of widely linear adaptive state space estimation techniques, which provide a unified framework and enhanced performance for the generality of complex signals, compared with conventional approaches. These include the linear and nonlinear Kalman and particle filters, whereby it is shown that catering for the complete second order information and system models leads to significant performance gains. The proposed techniques are also extended to the case of cooperative distributed estimation, where nodes in a network collaborate locally to estimate signals, under a framework that caters for general complex signals, as well as the cross-correlations between observation noises, unlike earlier solutions. The analysis of the algorithms are supported by numerous case studies, including frequency estimation in three phase power systems, DIFAR sonobuoy underwater target tracking, and real-world wind modeling and prediction.Open Acces