Analysis and Design of Radio Frequency Integrated Circuits for Breast Cancer Radar Imaging in CMOS Technology

Breast cancer is by far the most incident tumor among female population. Early stage prevention is a key factor in delivering long term survival of breast cancer patients. X-ray mammography is the most commonly used diagnostic technique to detect non-palpable tumors. However, 10-30% of tumors are missed by mammography and ionizing radiations together with breast compression do not lead to comfort in patient treatment. In this context, ultrawideband microwave radar technology is an attractive alternative. It relies on the dielectric contrast of normal and malignant tissues at microwave frequencies to detect and locate tumors inside the breast. This work presents the analysis and design of radio frequency integrated circuits for breast cancer imaging in CMOS technology. The first part of the thesis concerns the system analysis. A behavioral model of two different transceiver architectures for UWB breast cancer imaging employing a SFCW radar system are presented. A mathematical model of the direct conversion and super heterodyne architectures together with a numerical breast phantom are developed. FDTD simulations data are used to on the behavioral model to investigate the limits of both architectures from a circuit-level point of view. Insight is given into I/Q phase inaccuracies and their impact on the quality of the final reconstructed images. The result is that the simplicity of the direct conversion architecture makes the receiver more robust toward the critical impairments for this application. The second part of the thesis is dedicated to the circuit design. The main achievement is a 65nm CMOS 2-16GHz stepped frequency radar transceiver for medical imaging. The RX features 36dB conversion gain, >29dBm compression point, 7dB noise figure, and 30Hz 1/f noise corner. The TX outputs 14dBm with >40dBc harmonic rejection and <109dBc/Hz phase noise at 1MHz offset. Overall power dissipation is 204mW from 1.2V supply. The radar achieves 3mm resolution within the body, and 107dB dynamic range, a performance enabling the use for breast cancer diagnostic imaging. To further assess the capabilities of the proposed radar, a physical breast phantom was synthesized and two targets mimicking two tumors were buried inside the breast. The targets are clearly identified and correctly located, effectively proving the performance of the designed radar as a possible tool for breast cancer detection

Design of Fully-Integrated High-Resolution Radars in CMOS and BiCMOS Technologies

The RADAR, acronym that stands for RAdio Detection And ranging, is a device that uses electromagnetic waves to detect the presence and the distance of an illuminated target. The idea of such a system was presented in the early 1900s to determine the presence of ships. Later on, with the approach of World War II, the radar gained the interest of the army who decided to use it for defense purposes, in order to detect the presence, the distance and the speed of ships, planes and even tanks. Nowadays, the use of similar systems is extended outside the military area. Common applications span from weather surveillance to Earth composition mapping and from flight control to vehicle speed monitoring. Moreover, the introduction of new ultrawideband (UWB) technologies makes it possible to perform radar imaging which can be successfully used in the automotive or medical field. The existence of a plenty of known applications is the reason behind the choice of the topic of this thesis, which is the design of fully-integrated high-resolution radars. The first part of this work gives a brief introduction on high resolution radars and describes its working principle in a mathematical way. Then it gives a comparison between the existing radar types and motivates the choice of an integrated solution instead of a discrete one. The second part concerns the analysis and design of two CMOS high-resolution radar prototypes tailored for the early detection of the breast cancer. This part begins with an explanation of the motivations behind this project. Then it gives a thorough system analysis which indicates the best radar architecture in presence of impairments and dictates all the electrical system specifications. Afterwards, it describes in depth each block of the transceivers with particular emphasis on the local oscillator (LO) generation system which is the most critical block of the designs. Finally, the last section of this part presents the measurement results. In particular, it shows that the designed radar operates over 3 octaves from 2 to 16GHz, has a conversion gain of 36dB, a flicker-noise-corner of 30Hz and a dynamic range of 107dB. These characteristics turn into a resolution of 3mm inside the body, more than enough to detect even the smallest tumor. The third and last part of this thesis focuses on the analysis and design of some important building blocks for phased-array radars, including phase shifter (PHS), true time delay (TTD) and power combiner. This part begins with an exhaustive introduction on phased array systems followed by a detailed description of each proposed lumped-element block. The main features of each block is the very low insertion loss, the wideband characteristic and the low area consumption. Finally, the major effects of circuit parasitics are described followed by simulation and measurement results

Active positive sloped equalizer for x-band SiGe BiCMOS phased array applications

This work presents an active equalizer circuit with positive gain slope at X-Band (8 - 12 GHz). Compared to passive examples, the active equalizer realized better filter and impedance characteristics in frequency of interest with increased functionality for a single amplification stage. It achieved close to 10 dB of peak gain, a + 1.13 dB/GHz gain slope with 2.8 dB NF by utilizing cascode topology. The design reaches a -1.5 dBm input-referred compression point (input-P1dB) while consuming 46 mW of power. To the best of authors’ knowledge, the presented work achieves the best on-chip gain, a gain slope and NF performance in the literature as an equalizer that utilizes SiGe BiCMOS technology

Development of a Full-Field Time-of-Flight Range Imaging System

A full-field, time-of-flight, image ranging system or 3D camera has been developed from a proof-of-principle to a working prototype stage, capable of determining the intensity and range for every pixel in a scene. The system can be adapted to the requirements of various applications, producing high precision range measurements with sub-millimetre resolution, or high speed measurements at video frame rates. Parallel data acquisition at each pixel provides high spatial resolution independent of the operating speed. The range imaging system uses a heterodyne technique to indirectly measure time of flight. Laser diodes with highly diverging beams are intensity modulated at radio frequencies and used to illuminate the scene. Reflected light is focused on to an image intensifier used as a high speed optical shutter, which is modulated at a slightly different frequency to that of the laser source. The output from the shutter is a low frequency beat signal, which is sampled by a digital video camera. Optical propagation delay is encoded into the phase of the beat signal, hence from a captured time variant intensity sequence, the beat signal phase can be measured to determine range for every pixel in the scene. A direct digital synthesiser (DDS) is designed and constructed, capable of generating up to three outputs at frequencies beyond 100 MHz with the relative frequency stability in excess of nine orders of magnitude required to control the laser and shutter modulation. Driver circuits were also designed to modulate the image intensifier photocathode at 50 Vpp, and four laser diodes with a combined power output of 320 mW, both over a frequency range of 10-100 MHz. The DDS, laser, and image intensifier response are characterised. A unique method of measuring the image intensifier optical modulation response is developed, requiring the construction of a pico-second pulsed laser source. This characterisation revealed deficiencies in the measured responses, which were mitigated through hardware modifications where possible. The effects of remaining imperfections, such as modulation waveform harmonics and image intensifier irising, can be calibrated and removed from the range measurements during software processing using the characterisation data. Finally, a digital method of generating the high frequency modulation signals using a FPGA to replace the analogue DDS is developed, providing a highly integrated solution, reducing the complexity, and enhancing flexibility. In addition, a novel modulation coding technique is developed to remove the undesirable influence of waveform harmonics from the range measurement without extending the acquisition time. When combined with a proposed modification to the laser illumination source, the digital system can enhance range measurement precision and linearity. From this work, a flexible full-field image ranging system is successfully realised. The system is demonstrated operating in a high precision mode with sub-millimetre depth resolution, and also in a high speed mode operating at video update rates (25 fps), in both cases providing high (512 512) spatial resolution over distances of several metres

Ultra Wideband

Ultra wideband (UWB) has advanced and merged as a technology, and many more people are aware of the potential for this exciting technology. The current UWB field is changing rapidly with new techniques and ideas where several issues are involved in developing the systems. Among UWB system design, the UWB RF transceiver and UWB antenna are the key components. Recently, a considerable amount of researches has been devoted to the development of the UWB RF transceiver and antenna for its enabling high data transmission rates and low power consumption. Our book attempts to present current and emerging trends in-research and development of UWB systems as well as future expectations

Millimetre-Resolution Photonics-Assisted Radar

Radar is essential in applications such as anti-collision systems for driving, airport security screening, and contactless vital sign detection. The demand for high-resolution and real-time recognition in radar applications is growing, driving the development of electronic radars with increased bandwidth, higher frequency, and improved reconfigurability. However, conventional electronic approaches are challenging due to limitations in synthesising radar signals, limiting performance. In contrast, microwave photonics-enabled radars have gained interest because they offer numerous benefits compared to traditional electronic methods. Photonics-assisted techniques provide a broad fractional bandwidth at the optical carrier frequency and enable spectrum manipulation, producing wideband and high-resolution radar signals in various formats. However, photonic-based methods face limitations like low time-frequency linearity due to the inherent nonlinearity of lasers, restricted RF bandwidth, limited stability of the photonic frequency multipliers, and difficulties in achieving extended sensing with dispersion-based techniques. In response to these challenges, this thesis presents approaches for generating broadband radar signals with high time-frequency linearity using recirculated unidirectional optical frequency-shifted modulation. The photonics-assisted system allows flexible bandwidth tuning from sub-GHz to over 30 GHz and requires only MHz-level electronics. Such a system offers millimetre-level range resolution and a high imaging refresh rate, detecting fast-moving objects using the ISAR technique. With millimetre-level resolution and micrometre accuracy, this system supports contactless vital sign detection, capturing precise respiratory patterns from simulators and a living body using a cane toad. In the end, we highlight the promise of merging radar and LiDAR, foreshadowing future advancements in sensor fusion for enhanced sensing performance and resilience