Analysis and Design of Radio Frequency Integrated Circuits for Breast Cancer Radar Imaging in CMOS Technology

Breast cancer is by far the most incident tumor among female population. Early stage prevention is a key factor in delivering long term survival of breast cancer patients. X-ray mammography is the most commonly used diagnostic technique to detect non-palpable tumors. However, 10-30% of tumors are missed by mammography and ionizing radiations together with breast compression do not lead to comfort in patient treatment. In this context, ultrawideband microwave radar technology is an attractive alternative. It relies on the dielectric contrast of normal and malignant tissues at microwave frequencies to detect and locate tumors inside the breast. This work presents the analysis and design of radio frequency integrated circuits for breast cancer imaging in CMOS technology. The first part of the thesis concerns the system analysis. A behavioral model of two different transceiver architectures for UWB breast cancer imaging employing a SFCW radar system are presented. A mathematical model of the direct conversion and super heterodyne architectures together with a numerical breast phantom are developed. FDTD simulations data are used to on the behavioral model to investigate the limits of both architectures from a circuit-level point of view. Insight is given into I/Q phase inaccuracies and their impact on the quality of the final reconstructed images. The result is that the simplicity of the direct conversion architecture makes the receiver more robust toward the critical impairments for this application. The second part of the thesis is dedicated to the circuit design. The main achievement is a 65nm CMOS 2-16GHz stepped frequency radar transceiver for medical imaging. The RX features 36dB conversion gain, >29dBm compression point, 7dB noise figure, and 30Hz 1/f noise corner. The TX outputs 14dBm with >40dBc harmonic rejection and <109dBc/Hz phase noise at 1MHz offset. Overall power dissipation is 204mW from 1.2V supply. The radar achieves 3mm resolution within the body, and 107dB dynamic range, a performance enabling the use for breast cancer diagnostic imaging. To further assess the capabilities of the proposed radar, a physical breast phantom was synthesized and two targets mimicking two tumors were buried inside the breast. The targets are clearly identified and correctly located, effectively proving the performance of the designed radar as a possible tool for breast cancer detection

Circuits and Systems for On-Chip RF Chemical Sensors and RF FDD Duplexers

Integrating RF bio-chemical sensors and RF duplexers helps to reduce cost and area in the current applications. Furthermore, new applications can exist based on the large scale integration of these crucial blocks. This dissertation addresses the integration of RF bio-chemical sensors and RF duplexers by proposing these initiatives. A low power integrated LC-oscillator-based broadband dielectric spectroscopy (BDS) system is presented. The real relative permittivity ε’r is measured as a shift in the oscillator frequency using an on-chip frequency-to-digital converter (FDC). The imaginary relative permittivity ε”r increases the losses of the oscillator tank which mandates a higher dc biasing current to preserve the same oscillation amplitude. An amplitude-locked loop (ALL) is used to fix the amplitude and linearize the relation between the oscillator bias current and ε”r. The proposed BDS system employs a sensing oscillator and a reference oscillator where correlated double sampling (CDS) is used to mitigate the impact of flicker noise, temperature variations and frequency drifts. A prototype is implemented in 0.18 µm CMOS process with total chip area of 6.24 mm^2 to operate in 1-6 GHz range using three dual bands LC oscillators. The achieved standard deviation in the air is 2.1 ppm for frequency reading and 110 ppm for current reading. A tunable integrated electrical balanced duplexer (EBD) is presented as a compact alternative to multiple bulky SAW and BAW duplexers in 3G/4G cellular transceivers. A balancing network creates a replica of the transmitter signal for cancellation at the input of a single-ended low noise amplifier (LNA) to isolate the receive path from the transmitter. The proposed passive EBD is based on a cross-connected transformer topology without the need of any extra balun at the antenna side. The duplexer achieves around 50 dB TX-RX isolation within 1.6-2.2 GHz range up to 22 dBm. The cascaded noise figure of the duplexer and LNA is 6.5 dB, and TX insertion loss (TXIL) of the duplexer is about 3.2 dB. The duplexer and LNA are implemented in 0.18 µm CMOS process and occupy an active area of 0.35 mm^2

Advanced Trends in Wireless Communications

Physical limitations on wireless communication channels impose huge challenges to reliable communication. Bandwidth limitations, propagation loss, noise and interference make the wireless channel a narrow pipe that does not readily accommodate rapid flow of data. Thus, researches aim to design systems that are suitable to operate in such channels, in order to have high performance quality of service. Also, the mobility of the communication systems requires further investigations to reduce the complexity and the power consumption of the receiver. This book aims to provide highlights of the current research in the field of wireless communications. The subjects discussed are very valuable to communication researchers rather than researchers in the wireless related areas. The book chapters cover a wide range of wireless communication topics

Evaluating Techniques for Wireless Interconnected 3D Processor Arrays

In this thesis the viability of a wireless interconnect network for a highly parallel computer is investigated. The main theme of this thesis is to project the performance of a wireless network used to connect the processors in a parallel machine of such design. This thesis is going to investigate new design opportunities a wireless interconnect network can offer for parallel computing. A simulation environment is designed and implemented to carry out the tests. The results have shown that if the available radio spectrum is shared effectively between building blocks of the parallel machine, there are substantial chances to achieve high processor utilisation. The results show that some factors play a major role in the performance of such a machine. The size of the machine, the size of the problem and the communication and computation capabilities of each element of the machine are among those factors. The results show these factors set a limit on the number of nodes engaged in some classes of tasks. They have shown promising potential for further expansion and evolution of our idea to new architectural opportunities, which is discussed by the end of this thesis. To build a real machine of this type the architects would need to solve a number of challenging problems including heat dissipation, delivering electric power and Chip/board design; however, these issues are not part of this thesis and will be tackled in future