11,669 research outputs found
Precision medicine and artificial intelligence : a pilot study on deep learning for hypoglycemic events detection based on ECG
Tracking the fluctuations in blood glucose levels is important for healthy subjects and crucial diabetic patients. Tight glucose monitoring reduces the risk of hypoglycemia, which can result in a series of complications, especially in diabetic patients, such as confusion, irritability, seizure and can even be fatal in specific conditions. Hypoglycemia affects the electrophysiology of the heart. However, due to strong inter-subject heterogeneity, previous studies based on a cohort of subjects failed to deploy electrocardiogram (ECG)-based hypoglycemic detection systems reliably. The current study used personalised medicine approach and Artificial Intelligence (AI) to automatically detect nocturnal hypoglycemia using a few heartbeats of raw ECG signal recorded with non-invasive, wearable devices, in healthy individuals, monitored 24 hours for 14 consecutive days. Additionally, we present a visualisation method enabling clinicians to visualise which part of the ECG signal (e.g., T-wave, ST-interval) is significantly associated with the hypoglycemic event in each subject, overcoming the intelligibility problem of deep-learning methods. These results advance the feasibility of a real-time, non-invasive hypoglycemia alarming system using short excerpts of ECG signal
Multi-modal Approach for Affective Computing
Throughout the past decade, many studies have classified human emotions using
only a single sensing modality such as face video, electroencephalogram (EEG),
electrocardiogram (ECG), galvanic skin response (GSR), etc. The results of
these studies are constrained by the limitations of these modalities such as
the absence of physiological biomarkers in the face-video analysis, poor
spatial resolution in EEG, poor temporal resolution of the GSR etc. Scant
research has been conducted to compare the merits of these modalities and
understand how to best use them individually and jointly. Using multi-modal
AMIGOS dataset, this study compares the performance of human emotion
classification using multiple computational approaches applied to face videos
and various bio-sensing modalities. Using a novel method for compensating
physiological baseline we show an increase in the classification accuracy of
various approaches that we use. Finally, we present a multi-modal
emotion-classification approach in the domain of affective computing research.Comment: Published in IEEE 40th International Engineering in Medicine and
Biology Conference (EMBC) 201
Precision medicine and artificial intelligence : a pilot study on deep learning for hypoglycemic events detection based on ECG
Tracking the fluctuations in blood glucose levels is important for healthy subjects and crucial diabetic patients. Tight glucose monitoring reduces the risk of hypoglycemia, which can result in a series of complications, especially in diabetic patients, such as confusion, irritability, seizure and can even be fatal in specific conditions. Hypoglycemia affects the electrophysiology of the heart. However, due to strong inter-subject heterogeneity, previous studies based on a cohort of subjects failed to deploy electrocardiogram (ECG)-based hypoglycemic detection systems reliably. The current study used personalised medicine approach and Artificial Intelligence (AI) to automatically detect nocturnal hypoglycemia using a few heartbeats of raw ECG signal recorded with non-invasive, wearable devices, in healthy individuals, monitored 24 hours for 14 consecutive days. Additionally, we present a visualisation method enabling clinicians to visualise which part of the ECG signal (e.g., T-wave, ST-interval) is significantly associated with the hypoglycemic event in each subject, overcoming the intelligibility problem of deep-learning methods. These results advance the feasibility of a real-time, non-invasive hypoglycemia alarming system using short excerpts of ECG signal
Time series kernel similarities for predicting Paroxysmal Atrial Fibrillation from ECGs
We tackle the problem of classifying Electrocardiography (ECG) signals with
the aim of predicting the onset of Paroxysmal Atrial Fibrillation (PAF). Atrial
fibrillation is the most common type of arrhythmia, but in many cases PAF
episodes are asymptomatic. Therefore, in order to help diagnosing PAF, it is
important to design procedures for detecting and, more importantly, predicting
PAF episodes. We propose a method for predicting PAF events whose first step
consists of a feature extraction procedure that represents each ECG as a
multi-variate time series. Successively, we design a classification framework
based on kernel similarities for multi-variate time series, capable of handling
missing data. We consider different approaches to perform classification in the
original space of the multi-variate time series and in an embedding space,
defined by the kernel similarity measure. We achieve a classification accuracy
comparable with state of the art methods, with the additional advantage of
detecting the PAF onset up to 15 minutes in advance
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