The Parallelism Motifs of Genomic Data Analysis

Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these genomic data analysis problems require large scale computational platforms to meet both the memory and computational requirements. These applications differ from scientific simulations that dominate the workload on high end parallel systems today and place different requirements on programming support, software libraries, and parallel architectural design. For example, they involve irregular communication patterns such as asynchronous updates to shared data structures. We consider several problems in high performance genomics analysis, including alignment, profiling, clustering, and assembly for both single genomes and metagenomes. We identify some of the common computational patterns or motifs that help inform parallelization strategies and compare our motifs to some of the established lists, arguing that at least two key patterns, sorting and hashing, are missing

Using message logs and resource use data for cluster failure diagnosis

Failure diagnosis for large compute clusters using only message logs is known to be incomplete. Recent availability of resource use data provides another potentially useful source of data for failure detection and diagnosis. Early work combining message logs and resource use data for failure diagnosis has shown promising results. This paper describes the CRUMEL framework which implements a new approach to combining rationalized message logs and resource use data for failure diagnosis. CRUMEL identifies patterns of errors and resource use and correlates these patterns by time with system failures. Application of CRUMEL to data from the Ranger supercomputer has yielded improved diagnoses over previous research. CRUMEL has: (i) showed that more events correlated with system failures can only be identified by applying different correlation algorithms, (ii) confirmed six groups of errors, (iii) identified Lustre I/O resource use counters which are correlated with occurrence of Lustre faults which are potential flags for online detection of failures, (iv) matched the dates of correlated error events and correlated resource use with the dates of compute node hangups and (v) identified two more error groups associated with compute node hang-ups. The pre-processed data will be put on the public domain in September, 2016

Recent Advances in Fully Dynamic Graph Algorithms

In recent years, significant advances have been made in the design and analysis of fully dynamic algorithms. However, these theoretical results have received very little attention from the practical perspective. Few of the algorithms are implemented and tested on real datasets, and their practical potential is far from understood. Here, we present a quick reference guide to recent engineering and theory results in the area of fully dynamic graph algorithms

The Hardness of Optimization Problems on the Weighted Massively Parallel Computation Model

The topology-aware Massively Parallel Computation (MPC) model is proposed and studied recently, which enhances the classical MPC model by the awareness of network topology. The work of Hu et al. on topology-aware MPC model considers only the tree topology. In this paper a more general case is considered, where the underlying network is a weighted complete graph. We then call this model as Weighted Massively Parallel Computation (WMPC) model, and study the problem of minimizing communication cost under it. Two communication cost minimization problems are defined based on different pattern of communication, which are the Data Redistribution Problem and Data Allocation Problem. We also define four kinds of objective functions for communication cost, which consider the total cost, bottleneck cost, maximum of send and receive cost, and summation of send and receive cost, respectively. Combining the two problems in different communication pattern with the four kinds of objective cost functions, 8 problems are obtained. The hardness results of the 8 problems make up the content of this paper. With rigorous proof, we prove that some of the 8 problems are in P, some FPT, some NP-complete, and some W[1]-complete

APRIL: Approximating Polygons as Raster Interval Lists

The spatial intersection join an important spatial query operation, due to its popularity and high complexity. The spatial join pipeline takes as input two collections of spatial objects (e.g., polygons). In the filter step, pairs of object MBRs that intersect are identified and passed to the refinement step for verification of the join predicate on the exact object geometries. The bottleneck of spatial join evaluation is in the refinement step. We introduce APRIL, a powerful intermediate step in the pipeline, which is based on raster interval approximations of object geometries. Our technique applies a sequence of interval joins on 'intervalized' object approximations to determine whether the objects intersect or not. Compared to previous work, APRIL approximations are simpler, occupy much less space, and achieve similar pruning effectiveness at a much higher speed. Besides intersection joins between polygons, APRIL can directly be applied and has high effectiveness for polygonal range queries, within joins, and polygon-linestring joins. By applying a lightweight compression technique, APRIL approximations may occupy even less space than object MBRs. Furthermore, APRIL can be customized to apply on partitioned data and on polygons of varying sizes, rasterized at different granularities. Our last contribution is a novel algorithm that computes the APRIL approximation of a polygon without having to rasterize it in full, which is orders of magnitude faster than the computation of other raster approximations. Experiments on real data demonstrate the effectiveness and efficiency of APRIL; compared to the state-of-the-art intermediate filter, APRIL occupies 2x-8x less space, is 3.5x-8.5x more time-efficient, and reduces the end-to-end join cost up to 3 times.Comment: 12 page

An extensive study on iterative solver resilience : characterization, detection and prediction

Soft errors caused by transient bit flips have the potential to significantly impactan applicalion's behavior. This has motivated the design of an array of techniques to detect, isolate, and correct soft errors using microarchitectural, architectural, compilation­based, or application-level techniques to minimize their impact on the executing application. The first step toward the design of good error detection/correction techniques involves an understanding of an application's vulnerability to soft errors. This work focuses on silent data e orruption's effects on iterative solvers and efforts to mitigate those effects. In this thesis, we first present the first comprehensive characterizalion of !he impact of soft errors on !he convergen ce characteris tics of six iterative methods using application-level fault injection. We analyze the impact of soft errors In terms of the type of error (single-vs multi-bit), the distribution and location of bits affected, the data structure and statement impacted, and varialion with time. We create a public access database with more than 1.5 million fault injection results. We then analyze the performance of soft error detection mechanisms and present the comparalive results. Molivated by our observations, we evaluate a machine-learning based detector that takes as features that are the runtime features observed by the individual detectors to arrive al their conclusions. Our evalualion demonstrates improved results over individual detectors. We then propase amachine learning based method to predict a program's error behavior to make fault injection studies more efficient. We demonstrate this method on asse ssing the performance of soft error detectors. We show that our method maintains 84% accuracy on average with up to 53% less cost. We also show, once a model is trained further fault injection tests would cost 10% of the expected full fault injection runs.“Soft errors” causados por cambios de estado transitorios en bits, tienen el potencial de impactar significativamente el comportamiento de una aplicación. Esto, ha motivado el diseño de una variedad de técnicas para detectar, aislar y corregir soft errors aplicadas a micro-arquitecturas, arquitecturas, tiempo de compilación y a nivel de aplicación para minimizar su impacto en la ejecución de una aplicación. El primer paso para diseñar una buna técnica de detección/corrección de errores, implica el conocimiento de las vulnerabilidades de la aplicación ante posibles soft errors. Este trabajo se centra en los efectos de la corrupción silenciosa de datos en soluciones iterativas, así como en los esfuerzos para mitigar esos efectos. En esta tesis, primeramente, presentamos la primera caracterización extensiva del impacto de soft errors sobre las características convergentes de seis métodos iterativos usando inyección de fallos a nivel de aplicación. Analizamos el impacto de los soft errors en términos del tipo de error (único vs múltiples-bits), de la distribución y posición de los bits afectados, las estructuras de datos, instrucciones afectadas y de las variaciones en el tiempo. Creamos una base de datos pública con más de 1.5 millones de resultados de inyección de fallos. Después, analizamos el desempeño de mecanismos de detección de soft errors actuales y presentamos los resultados de su comparación. Motivados por las observaciones de los resultados presentados, evaluamos un detector de soft errors basado en técnicas de machine learning que toma como entrada las características observadas en el tiempo de ejecución individual de los detectores anteriores al llegar a su conclusión. La evaluación de los resultados obtenidos muestra una mejora por sobre los detectores individualmente. Basados en estos resultados propusimos un método basado en machine learning para predecir el comportamiento de los errores en un programa con el fin de hacer el estudio de inyección de errores mas eficiente. Presentamos este método para evaluar el rendimiento de los detectores de soft errors. Demostramos que nuestro método mantiene una precisión del 84% en promedio con hasta un 53% de mejora en el tiempo de ejecución. También mostramos que una vez que un modelo ha sido entrenado, las pruebas de inyección de errores siguientes costarían 10% del tiempo esperado de ejecución.Postprint (published version

A systematic review on cloud storage mechanisms concerning e-healthcare systems

As the expenses of medical care administrations rise and medical services experts are becoming rare, it is up to medical services organizations and institutes to consider the implementation of medical Health Information Technology (HIT) innovation frameworks. HIT permits health associations to smooth out their considerable cycles and offer types of assistance in a more productive and financially savvy way. With the rise of Cloud Storage Computing (CSC), an enormous number of associations and undertakings have moved their healthcare data sources to distributed storage. As the information can be mentioned whenever universally, the accessibility of information becomes an urgent need. Nonetheless, outages in cloud storage essentially influence the accessibility level. Like the other basic variables of cloud storage (e.g., reliability quality, performance, security, and protection), availability also directly impacts the data in cloud storage for e-Healthcare systems. In this paper, we systematically review cloud storage mechanisms concerning the healthcare environment. Additionally, in this paper, the state-of-the-art cloud storage mechanisms are critically reviewed for e-Healthcare systems based on their characteristics. In short, this paper summarizes existing literature based on cloud storage and its impact on healthcare, and it likewise helps researchers, medical specialists, and organizations with a solid foundation for future studies in the healthcare environment.Qatar University [IRCC-2020-009]

Parallel Working-Set Search Structures

In this paper we present two versions of a parallel working-set map on p processors that supports searches, insertions and deletions. In both versions, the total work of all operations when the map has size at least p is bounded by the working-set bound, i.e., the cost of an item depends on how recently it was accessed (for some linearization): accessing an item in the map with recency r takes O(1+log r) work. In the simpler version each map operation has O((log p)^2+log n) span (where n is the maximum size of the map). In the pipelined version each map operation on an item with recency r has O((log p)^2+log r) span. (Operations in parallel may have overlapping span; span is additive only for operations in sequence.) Both data structures are designed to be used by a dynamic multithreading parallel program that at each step executes a unit-time instruction or makes a data structure call. To achieve the stated bounds, the pipelined data structure requires a weak-priority scheduler, which supports a limited form of 2-level prioritization. At the end we explain how the results translate to practical implementations using work-stealing schedulers. To the best of our knowledge, this is the first parallel implementation of a self-adjusting search structure where the cost of an operation adapts to the access sequence. A corollary of the working-set bound is that it achieves work static optimality: the total work is bounded by the access costs in an optimal static search tree.Comment: Authors' version of a paper accepted to SPAA 201

A Study of High Performance Multiple Precision Arithmetic on Graphics Processing Units

Multiple precision (MP) arithmetic is a core building block of a wide variety of algorithms in computational mathematics and computer science. In mathematics MP is used in computational number theory, geometric computation, experimental mathematics, and in some random matrix problems. In computer science, MP arithmetic is primarily used in cryptographic algorithms: securing communications, digital signatures, and code breaking. In most of these application areas, the factor that limits performance is the MP arithmetic. The focus of our research is to build and analyze highly optimized libraries that allow the MP operations to be offloaded from the CPU to the GPU. Our goal is to achieve an order of magnitude improvement over the CPU in three key metrics: operations per second per socket, operations per watt, and operation per second per dollar. What we find is that the SIMD design and balance of compute, cache, and bandwidth resources on the GPU is quite different from the CPU, so libraries such as GMP cannot simply be ported to the GPU. New approaches and algorithms are required to achieve high performance and high utilization of GPU resources. Further, we find that low-level ISA differences between GPU generations means that an approach that works well on one generation might not run well on the next. Here we report on our progress towards MP arithmetic libraries on the GPU in four areas: (1) large integer addition, subtraction, and multiplication; (2) high performance modular multiplication and modular exponentiation (the key operations for cryptographic algorithms) across generations of GPUs; (3) high precision floating point addition, subtraction, multiplication, division, and square root; (4) parallel short division, which we prove is asymptotically optimal on EREW and CREW PRAMs