1,169 research outputs found
A Weaker Version of Continuity and a Common Fixed Point Theorem
A generalization of results of the second author [4] and the authors [5] have been proved through the notions of property E.A. and weak compatibility and restricting the orbital completeness of the space. 2000 AMS mathematics subject classification: 54 H 25 Key Words: Compatible self-maps, weakly compatible self-maps, property EA and common fixed poin
On Classification with Bags, Groups and Sets
Many classification problems can be difficult to formulate directly in terms
of the traditional supervised setting, where both training and test samples are
individual feature vectors. There are cases in which samples are better
described by sets of feature vectors, that labels are only available for sets
rather than individual samples, or, if individual labels are available, that
these are not independent. To better deal with such problems, several
extensions of supervised learning have been proposed, where either training
and/or test objects are sets of feature vectors. However, having been proposed
rather independently of each other, their mutual similarities and differences
have hitherto not been mapped out. In this work, we provide an overview of such
learning scenarios, propose a taxonomy to illustrate the relationships between
them, and discuss directions for further research in these areas
T(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: An international study of 62 patients
Acute myeloid leukemia with t(6;9)(p22;q34) is listed as a distinct entity in the 2008 World Health Organization classification, but little is known about the clinical implications of t(6;9)-positive myeloid leukemia in children. This international multicenter study presents the clinical and genetic characteristics of 62 pediatric patients with t(6;9)/DEK-NUP214-rearranged myeloid leukemia; 54 diagnosed as having acute myeloid leukemia, representing <1% of all childhood acute myeloid leukemia, and eight as having myelodysplastic syndrome. The t(6;9)/DEK-NUP214 was associated with relatively late onset (median age 10.4 years), male predominance (sex ratio 1.7), French-American-British M2 classification (54%), myelodysplasia (100%), and FLT3-ITD (42%). Outcome was substantially better than previously reported with a 5-year event-free survival of 32%, 5-year overall survival of 53%, and a 5-year cumulative incidence of relapse of 57%. Hematopoietic stem cell transplantation in first complete remission improved the 5-year event-free survival compared with chemotherapy alone (68% versus 18%; P<0.01) but not the overall survival (68% versus 54%; P=0.48). The presence of FLT3-ITD had a non-significant negative effect on 5-year overall survival compared with non-mutated cases (22% versus 62%; P=0.13). Gene expression profiling showed a unique signature characterized by significantly higher expression of EYA3, SESN1, PRDM2/RIZ, and HIST2H4 genes. In conclusion, t(6;9)/DEK-NUP214 represents a unique subtype of acute myeloid leukemia with a high risk of relapse, high frequency of FLT3-ITD, and a specific gene expression signature
New ILAE versus previous clinical status epilepticus semiologic classification: Analysis of a hospital-based cohort.
OBJECTIVES: In 2015, the International League Against Epilepsy (ILAE) issued a new status epilepticus (SE) classification, including a detailed semiologic axis. This study assesses frequencies of SE forms in a cohort of adult patients, and explores differences and practical implications as compared to a seizure-type-bound classification.
METHODS: The prospective adult SE registry of the Lausanne University Hospital (CHUV) was considered over 5 years (2011-2015); each SE episode was retrospectively reclassified for its semiology according to the new ILAE scheme. Mortality rates were retrieved for each subgroup of SE.
RESULTS: Among 488 SE episodes, according to the seizure-type-bound classification, 230 (47%) had a generalized convulsive, and 29 (6%) had a nonconvulsive SE in coma; both categories overlapped almost perfectly between the two classifications. However, the 84 episodes with focal SE without consciousness impairment and the 141 episodes with consciousness impairment were each translated into two major (and five sub-) categories of the new ILAE classification, having markedly different mortality rates. In addition, of 140 episodes labeled as focal motor SE according to the new classification, 54% had concomitant consciousness impairment, whereas 46% did not; again, mortality rates were heterogeneous.
SIGNIFICANCE: Although generalized convulsive and nonconvulsive SE in coma show an almost perfect correspondence across SE semiologic classifications, focal SE is markedly heterogeneous and appears to be better reflected in the new classification, offering more clinically relevant subdivisions, also differing in mortality rates. This refined knowledge may allow the development of clinical prognostic scores that are more precise than existing tools, and should be taken into account for epidemiologic studies
THE INFLUENCE OF ACCOUNTING STUDENT MORAL REASONING AND ETHICAL SENSITIVITY TOWARD UNETHICAL ACADEMIC BEHAVIOUR
In the context of education in Indonesia, the phenomenon about the
deterioration of moral values has become a kind of red light urging all parties, to
immediately see an important synergy for the development of character education.
Professional assessment cannot be separated from the basic value of honesty. This
study aims to determine the influence of accounting student moral reasoning and
ethical sensitivity toward unethical academic behaviour.
The samples in this study are 200 respondents and the questionnaires were
distributed to the accounting major student of economic and business faculty in
Diponegoro University, Semarang. All questions were measured using a Likert
scale with 5 rank answers from never to always. The data were processed using
SPSS 23. Data analysis method used is quantitative analysis using validity test,
reliability test, normality test, classic assumption test, multiple linear regression
analysis tests, t-test, and f-test.
The result of this study showed that the moral reasoning and ethical
sensitivity variables have a significant influence on unethical academic behaviour
on an accounting student who is studying accounting major in Diponegoro
University, Semarang
Josef Meixner: his life and his orthogonal polynomials
This paper starts with a biographical sketch of the life of Josef Meixner.
Then his motivations to work on orthogonal polynomials and special functions
are reviewed. Meixner's 1934 paper introducing the Meixner and
Meixner-Pollaczek polynomials is discussed in detail. Truksa's forgotten 1931
paper, which already contains the Meixner polynomials, is mentioned. The paper
ends with a survey of the reception of Meixner's 1934 paper.Comment: v4: 18 pages, generating function for Krawtchouk polynomials on p.10
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