Benchmark of murine T-cell epitope predictions based on comparative models.
Abstract
Benchmark of murine T-cell epitope predictions based on comparative models.</p- Dataset
- Dataset
- Biochemistry
- Biotechnology
- Immunology
- Infectious Diseases
- Biological Sciences not elsewhere classified
- Chemical Sciences not elsewhere classified
- Information Systems not elsewhere classified
- HLA-DR 1-restricted factor VIII epitope
- single-stage epitope prediction algorithms
- MHC class II
- 24 benchmark cases
- TCR recognition
- epitope predictions
- APC
- 12- mer peptide
- input protein antigen sequence
- method
- 20 peptide-MHCII-TCR crystal structures
- bind HLA-DR 1
- antigen cleavage sites
- factor VIII replacement therapy
- ternary peptide-MHCII-TCR complexes
- antigen cleavage
- T-cell epitopes
- MHCII presentation
- factor VIII-specific TCR sequences
- TCR sequences
- CD 4 T-cell epitopes
- top-scoring factor VIII peptides
- peptide-MHCII complexes