A Gold(III) Ion-Selective Fluorescent Probe and Its Application to Bioimagings

Abstract

A highly selective and sensitive fluorescent chemosensor for Au3+ has been reported. The system utilizes an irreversible Au3+-promoted cyclization reaction of a rhodamine amide tethered with an alkyne. The probe can sense Au3+ ions selectively over other biologically relevant metal ions, and ∼50 nM of Au3+ could be readily detected in aqueous media. Fluorescent imaging of Au3+ in living cells is also successfully demonstrated

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The Francis Crick Institute

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Last time updated on 16/03/2018

This paper was published in The Francis Crick Institute.

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