Highly Chemoselective Reduction of Carbonyl Groups in the Presence of Aldehydes
Abstract
The exquisite ability of diethylaluminum benzenethiolate to efficiently discriminate between aldehydes and other carbonyl functions enables the chemoselective <i>in situ</i> reduction of ketones and methyl esters in the presence of aldehydes. This potent strategy avoids the usual drawbacks of traditional protecting group methodologies and could be extended to various other transformations- Text
- Journal contribution
- Biophysics
- Biochemistry
- Neuroscience
- Ecology
- Cancer
- Infectious Diseases
- AldehydesThe
- presence
- Chemoselective Reduction
- methodology
- strategy
- drawback
- aldehyde
- transformation
- Carbonyl Groups
- ability
- methyl esters
- carbonyl functions
- diethylaluminum benzenethiolate
- chemoselective
- Presence
- ketone
- group methodologies
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Last time updated on 16/03/2018
This paper was published in The Francis Crick Institute.
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