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Screening for the foldameric recognition segments.

By Lívia Fülöp (146422), István M. Mándity (146427), Gábor Juhász (752374), Viktor Szegedi (134818), Anasztázia Hetényi (146434), Edit Wéber (146440), Zsolt Bozsó (146443), Dóra Simon (146447), Mária Benkő (146452), Zoltán Király (146457) and Tamás A. Martinek (146462)

Abstract

<p>Informative regions of the STD spectra (<b>A</b>–<b>F</b> for <b>1</b>–<b>6</b>, respectively) in the presence of Aβ(1–42) oligomers. The spectra were recorded in 20 mM phosphate buffer at pH 7.4, the total concentration of the Aβ(1–42) was 72 μM, and the ligands were applied at 2 mM. The secondary structure type is indicated to the right of the structures. ‘H’ stands for helix, and the numbers show the size of the H-bonded pseudocycles stabilizing the helices.</p

Topics: Biochemistry, Neuroscience, Chemistry, foldameric
Year: 2012
DOI identifier: 10.1371/journal.pone.0039485.g002
OAI identifier: oai:figshare.com:article/270090
Provided by: FigShare
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