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Changes in the ultrastructure of rat intestinal capillaries.

By Han Luo (302386), Ping Guo (302387) and Qiquan Zhou (302389)

Abstract

<p><b>A</b> In the control group, lanthanum particles were only distributed on capillary lumens; no La<sup>3+</sup> sediment was observed on the basement membrane lateral or extravascular mesenchyme. The morphology of nuclei and organelles such as mitochondria and the Golgi complex was normal. TEM, ×8900. <b>B</b> In the hypoxia group, La<sup>3+</sup> particles were distributed along the vessel basement membrane. Mild swelling of the organelles was observed. TEM, ×8900. <b>C</b> In the hypoxia group, many La<sup>3+</sup> particles were found to penetrate the basement membrane through the vessel TJs into tissue space, and La<sup>3+</sup> sediments were observed in the tissues of surrounding vessel. TEM, ×8900. <b>D</b> In the HP group, La<sup>3+</sup> particles were limited to capillary lumens. No see La<sup>3+</sup> sediment on the basement membrane lateral or surrounding mesenchyme. No notable abnormalities of organelles were found. TEM, ×8900. <b>E</b> In the HL group, La<sup>3+</sup> particles were distributed diffusively in the vessel the inside of basement membrane, A large number of La<sup>3+</sup> particles penetrate the basement membrane into the TJs, the surrounding vessel endothelial TJs space were enlarged. TEM, ×8900. <b>F</b> In the HPL group, La<sup>3+</sup> particles were distributed in vessel lumens, and only in the local endothelial basement membrane. No La<sup>3+</sup> particles were observed in the tissue space of surrounding vessel. TEM, ×8900.</p

Topics: Medicine, Cell Biology, Chemistry, Infectious Diseases, ultrastructure, intestinal
Year: 2013
DOI identifier: 10.1371/journal.pone.0046291.g002
OAI identifier: oai:figshare.com:article/226974
Provided by: FigShare
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