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Modafinil treatment prevents METH-induced increase of pro-apoptotic and decrease of anti-apoptotic markers in the striatum.

By Mariana Raineri (304307), Betina Gonzalez (304308), Belen Goitia (304309), Edgar Garcia-Rill (304310), Irina N. Krasnova (223517), Jean Lud Cadet (176223), Francisco J. Urbano (304311) and Veronica Bisagno (304312)

Abstract

<p>Expression of pro-apoptotic BAX (A) and anti-apoptotic Bcl2 (B) proteins in the striatum, measured by Western blot analyses. Striata were obtained 16 hours after VEH, MOD, METH or M+M treatments (n = 5−9).Values represent mean ± SEM (% of control). One-way ANOVA followed by Fisher’s LSD. different letters: p<0.05.</p

Topics: Neuroscience, Pharmacology, Mental Health, prevents, meth-induced, pro-apoptotic, anti-apoptotic, markers
Year: 2013
DOI identifier: 10.1371/journal.pone.0046599.g006
OAI identifier: oai:figshare.com:article/235091
Provided by: FigShare
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