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Model of the structure of MSPβ/RON Sema complex.

By Natalia Gorlatova (340263), Kinlin Chao (340264), Lipika R. Pal (13807), Rawan Hanna Araj (340266), Andrey Galkin (340269), Illarion Turko (340271), John Moult (62397) and Osnat Herzberg (314488)

Abstract

<p>Arg689 and the location of the α/β cleavage site are highlighted in magenta color. The molecular surfaces are shown in transparent colors. The model was built by super positioning the crystal structures of MSPβ <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027269#pone.0027269-Carafoli1" target="_blank">[22]</a> (PDB entry 1ASU) and RON-Sema-PSI (Chao and Herzberg, unpublished) on the crystal structure of the HGFβ/MET-Sema-PSI complex <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027269#pone.0027269-Stamos1" target="_blank">[29]</a> (PDB entry 1SHY). In this model, Arg689 is not directly involved in the RON/MSP interface.</p

Topics: Biophysics, Biochemistry, Molecular Biology, Chemistry, Immunology, Biological Sciences, sema
Year: 2013
DOI identifier: 10.1371/journal.pone.0027269.g006
OAI identifier: oai:figshare.com:article/386782
Provided by: FigShare
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