Article thumbnail

Delivery of S14G-HN to brain by intranasal administration.

By Takako Niikura (357548), Elkhansa Sidahmed (357550), Chiho Hirata-Fukae (357552), Paul S. Aisen (182509) and Yasuji Matsuoka (259420)

Abstract

<p>3xTg-AD mice (13 month-old) were intranasally administrated with S14G-HN (B) or vehicle (A), and sacrificed after 1 hour of administration. Brains were fixed with 4% paraformaldehyde and 30 µm sagittal sections of brains were subjected to immunostaining using anti-HN antibody (P04) and biotin-conjugated secondary antibody followed by visualization with avidin-fluorescein. ACB, Nucleus accumbens; AON, Anterior olfactory nucleus; NBD, Diagnal band nucleus; OT, Olfactory tubercle; SI, Substantia innominata. Bar = 500 µm.</p

Topics: Cell Biology, Neuroscience, s14g-hn, intranasal
Year: 2013
DOI identifier: 10.1371/journal.pone.0016259.g001
OAI identifier: oai:figshare.com:article/476305
Provided by: FigShare
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://figshare.com/articles/... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.