Delivery of S14G-HN to brain by intranasal administration.

Takako Niikura (357548); Elkhansa Sidahmed (357550); Chiho Hirata-Fukae (357552); Paul S. Aisen (182509); Yasuji Matsuoka (259420)

Delivery of S14G-HN to brain by intranasal administration.

Authors: Takako Niikura (357548)
Elkhansa Sidahmed (357550)
Chiho Hirata-Fukae (357552)
Paul S. Aisen (182509)
Yasuji Matsuoka (259420)
Publication date: 2013
Publisher
Doi

Abstract

<p>3xTg-AD mice (13 month-old) were intranasally administrated with S14G-HN (B) or vehicle (A), and sacrificed after 1 hour of administration. Brains were fixed with 4% paraformaldehyde and 30 µm sagittal sections of brains were subjected to immunostaining using anti-HN antibody (P04) and biotin-conjugated secondary antibody followed by visualization with avidin-fluorescein. ACB, Nucleus accumbens; AON, Anterior olfactory nucleus; NBD, Diagnal band nucleus; OT, Olfactory tubercle; SI, Substantia innominata. Bar = 500 µm.</p

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Last time updated on 16/03/2018

This paper was published in FigShare.

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