<p></p> <p>A series of polyfunctionalized anthraquinonehydrazones have been prepared using azo-coupling reaction between anthraquinone-based triazenes and methylene active compounds in acetic acid without a catalyst. The structures of new synthesized compounds were confirmed by their IR, LCMS,<sup>1</sup>H and <sup>13</sup>C NMR spectroscopic data. Some of the synthesized compounds were screened for their <i>in vitro</i> anticancer activity according to US NCI protocols. Biological screening data led to the identification of 1-{N’-[3-(4-hydroxyphenyl)-4-oxo-2-thioxothiazolidin-5-ylidene]hydrazino}anthraquinone <b>3.4</b> as having antitumor activity on the non-small cell lung cancer NCI-H460 (GP = 13.25%) and colon cancer HCT-116 (GP = 13.69%) cell lines.</p
Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.