<div><p>The antiradical activity of the freshwater bryozoan <i>Hyalinella punctata</i> water extracts (two samples, seasonal collection) was evaluated by using electron paramagnetic resonance spectroscopy against hydroxyl (√OH), superoxide anion (√O<sub>2</sub><sup>− </sup>), methoxy (√CH<sub>2</sub>OH), carbon-dioxide anion (√CO<sub>2</sub><sup>− </sup>), nitric-oxide (√NO) and 2,2-diphenyl-1-picrylhydrazyl (√DPPH) radicals. The extracts reduced the production of all tested radicals but to a varying degree. The better activity was observed against √CO<sub>2</sub><sup>− </sup> and √CH<sub>2</sub>OH radicals (54 ± 5% and 44 ± 4%, and 58 ± 6% and 22 ± 2%, respectively) than towards √DPPH, √NO, √OH and √O<sub>2</sub><sup>− </sup> radicals (59 ± 6% and 1.0 ± 0.1%, 46 ± 5% and 14 ± 1%, 7.0 ± 0.5% and 34 ± 3%, and 33 ± 3% and 0%, respectively). FTIR spectra of the both extracts indicate the presence of cyclic peptides and polypeptides which might be responsible for the observed activity. According to the experimental data obtained, <i>H. punctata</i> water extract may be considered as a novel promising resource of natural products with anti √CO<sub>2</sub><sup>− </sup> radical activity.</p></div
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