Efficient multicomponent synthesis of spiro[indoline-3,4′-thiopyran]-2-ones

Abstract

<p>Synthesis of new thiopyran fused spirooxindoles (spiro[indoline-3,4′-thiopyran]-2-ones) were achieved by a multicomponent reaction of <i>N</i>-methyl isatin, malononitrile/ethyl cyanoacetate, and β-oxodithioester using <i>N,N</i>′-dimethylaminopyridine as the catalyst.</p