Efficient Method of Moments Analysis of Periodic Metasurfaces Combining Spectral and Spatial Domain Approaches

This paper presents an efficient Method of Moments (MoM) formulation for the analysis of periodic metasurface (MTS) antennas. Whereas the periodic MoM matrix can be computed in spatial or spectral domains, its slowly convergent behavior in both domains directly impacts its computation time. In this work, it is proposed to accelerate the MoM matrix computation time through an appropriate combination of spectral and spatial domain approaches. This will be particularly well suited for the analysis of embedded element patterns of infinite periodic structures as the latter can be obtained using the periodic MoM for each direction of observation. Validation results are shown for two different MTS implementations, with details of the computation times

Tumor Segmentation on PSMA PET/CT Predicts Survival in Biochemical Recurrence of Prostate Cancer: A Retrospective Study Using [Ga]Ga-PSMA-11 and [F]-PSMA-1007.

PSMA PET/CT imaging has become a cornerstone in the management of prostate cancer, particularly in the setting of biochemical recurrence (BCR). While semi-quantitative parameters such as SUVmean have been evaluated as prognostic biomarkers in metastatic castration-resistant prostate cancer (mCRPC), particularly after the VISION trial, the prognostic role of volumetric measures such as Total Molecular Volume (TMV) remain largely unexplored, especially in earlier stages of the disease such as in biochemical recurrence following primary treatment. This retrospective monocentric study included 84 patients with BCR who underwent PSMA PET/CT imaging between 2020 and 2021 using either [Ga]Ga-PSMA-11(Ga-PSMA) or [F]-PSMA-1007 (F-PSMA) as tracers. Total tumor burden was assessed through manual 3D segmentation to derive whole-body Total Molecular Volume (wb TMV) and Total Lesion PSMA (wb TL-PSMA). Clinical and imaging variables were correlated with overall survival (OS) and progression-free survival (PFS) using Cox regression models. Kaplan-Meier analyses were performed based on wb TMV and thresholds determined by the Youden index. A PSMA PET/CT correlation for BCR was identified in 69% of patients, with comparable detection rates between tracers (Ga-PSMA 67% vs. F-PSMA 63%, = 0.7). A higher wb TMV was significantly associated with worse OS (HR 2.20, 2.87 exhibited significantly poorer survival outcomes. A PSA at diagnosis > 17 ng/mL also predicted shorter PFS. Tumor segmentation from PSMA PET/CT imaging provides powerful prognostic information in patients with biochemical recurrence of prostate cancer, independently of the tracer used. The wb TMV represents a promising volumetric biomarker for future risk stratification and therapeutic decision-making, particularly in earlier stages of prostate cancer progression, where predictive imaging biomarkers remain largely undefined

A nationwide comprehensive genomic profiling and molecular tumor board platform for patients with advanced cancer

The Belgian Approach for Local Laboratory Extensive Tumor Testing (BALLETT) study assessed the feasibility of using comprehensive genomic profiling (CGP) in clinical decision-making for patients with advanced cancers. This multi-center study enrolled 872 patients from 12 Belgian hospitals. CGP was performed on tumor tissues using a standardized CGP panel (523 genes) across nine laboratories with success in 93% of patients and a median turnaround time of 29 days. Actionable genomic markers were identified in 81% of patients, substantially higher than the 21% using nationally reimbursed, small panels. A national molecular tumor board (nMTB) recommended treatments for 69% of patients, with 23% receiving matched therapies. Reasons for non-compliance were highly variable across clinical sites. Overall, BALLETT demonstrates the feasibility of implementing decentralized CGP and its potential to identify actionable targets in most patients with advanced cancers. BALLETT reinforces CGP's utility and emphasizes the importance of collaboration, standardization, and addressing implementation challenges

Vers une XR éthique et engageante : mesure de l'expérience, enjeux du consentement et risques de surengagement

Ce poster présente 3 thèses financées par le projet Wal4XR : · Définir l'expérience utilisateur en réalité étendue et repenser les méthodes d’évaluation dans ce contexte multimodal et multisensoriel. • Repenser le consentement en XR comme un processus dynamique, évolutif et rétractable à tout moment. • Analyser le surengagement en VR gamifié en particulier dans les environnements professionnel

Orientation advantage in human face recognition : why so horizontal?

Face processing is a core component of human social interactions, from the ability to detect a face to the comprehension of what it conveys, in terms of age, identity, emotion... This work aims at further the understanding of the diagnostic information at play in such essential processes. Previous studies demonstrated that face processing differed as a function of the orientation of face information, with an advantage for the horizontal range. In line with these results, we focused on the orientation of face information, to determine how this advantage could be explained. Along 4 different angles, we aimed at extending the comprehension of the horizontal advantage through thorough investigation of oriented face information. First, we focused on the reference frame of this horizontal advantage. More specifically, we dissociated the observer’s reference frame and the face’s reference frame during a face recognition task. We found that albeit a small influence of the observer reference frame, the horizontal advantage of face identity categorization is image centered. Having determined that it was the face information and not the orientation per se that was important, we then focused in the two following chapters on this oriented information, and why it is more diagnostic of identity than other ranges. First, in an identity recognition task, through the use of inversion and negation, disrupting shape and surface-shading cues processing, we found that the horizontal was the orientation range that was the most affected by these manipulations. As shape and surface-shading cues have been demonstrated to be essential sources of information in face identity categorization, we demonstrated that the horizontal range, more than other orientation ranges of information, conveys essential face perception cues. In a second phase, through analysis of the orientation dependency of identity recognition across views, we showed that it was the horizontal range that yielded best view-tolerant recognition. Further analysis of the image content enabled to conclude that the horizontal range conveys the most informative identity cues at frontal views, and the most stable ones across different views. Finally, we tested whether the horizontal preference was solely found at finer categorization levels like identity and emotion processing, or whether basic-level categorization was also tuned to the horizontal information. Using fast periodic visual stimulation coupled with EEG and a similar behavioral experiment, to measure face categorization amongst various stimuli, we found that the horizontal and neighboring ranges yielded better basic-level categorization. These results suggest that the horizontal and neighboring ranges of face information convey better diagnostic cues for basic-level face categorization than the vertical range. In summary, the horizontal face information conveys face processing essential cues to a greater extent than other orientation ranges. This information is also the most informative at full front views as well as the most stable, enabling view-tolerant face recognition, thus accounting for the horizontal preference of face processing. As this horizontal advantage is found at multiple levels of face processing, the horizontal range seems to conveys diagnostic cues enabling the recruitment of face specialized mechanisms.(PSYE - Sciences psychologiques et de l'éducation) -- UCL, 202

Le phénomène de la vie végétale à partir de Hans Jonas : pour une biologie compréhensive

This PhD thesis proposes a contribution to contemporary debates on the philosophy of plants, more specifically in the perspective of the opening of Hans Jonas's thought (relevance, limits and trans-Jonasian orientations). From "the plant-resource" to "the plant being", the thesis attempts to take the plant out of its quasi-unthought (in the philosophical tradition), on both the ontological and phenomenological levels, by showing to what extent the biological categories at the heart of Jonas's theory of metabolism make it possible to open up new perspectives in the way of reproblematizing the hetero-organizational interiority of plant life. The plant thus becomes a driving force for philosophical reflection. The thesis successively discusses biosemiotic expressiveness, freedom in a contiguous context, antinomic autonomy, physiological complexity, behavior, the bodily anchoring of practical cognition, processual individuality, biological interactions, heteronomous temporality, co-evolutionary spatiality and self-purpose (self-preservation and self-presentation). It leads to the concept of "comprehensive biology", based on a hermeneutic approach in the dual sense of interpreting how the significantly interprets its environment and how humans understand these interpretations. This hermeneutics establishes a dialogue between scientific observation, analogy and empathic observation. In an era of systemic crises, it becomes indispensable to re-examine the profound otherness of plants, with the aim of finding schemes capable of re-establishing coexistence within living beings, the habitability of our planet, and our own social viability.Cette thèse propose une contribution aux débats contemporains sur la philosophie du végétal, plus spécifiquement dans la perspective de l’ouverture de la pensée de Hans Jonas (pertinence, limites et orientations trans-jonassiennes). De « la plante-ressource » à « l’être végétal », la thèse tente de sortir le végétal de son quasi-impensé (dans la tradition philosophique), sur les plans ontologique et phénoménologique, en montrant à quel point les catégories biologiques au cœur de la théorie jonassienne du métabolisme permettent d’ouvrir des perspectives inédites dans la manière de reproblématiser l’intériorité hétéro-organisationnelle de la vie végétale. Le végétal devient ainsi un moteur de réflexion philosophique. La thèse discute tour à tour de l’expressivité biosémiotique, de la liberté en contexte contigu, de l’autonomie antinomique, de la complexité physiologique, du comportement, de l’ancrage corporel de la cognition pratique, de l’individualité processuelle, des interactions biologiques, de la temporalité hétéronome, de la spatialité co-évolutive et de la finalité propre (autoconservation et autoprésentation). Elle aboutit au concept de « biologie compréhensive », axé sur une approche herméneutique au double sens de l’interprétation de la manière dont le vivant interprète significativement son milieu et dont l’humain comprend ces interprétations. Cette herméneutique établit un dialogue entre l’observation scientifique, l’analogie et l’observation empathique. À l’heure des crises systémiques, il s’avère indispensable de requestionner l’altérité profonde du végétal, dans le but d’y trouver des schèmes susceptibles de refonder la coexistence au sein du vivant, l’habitabilité de notre planète et notre viabilité sociale.(FILO - Philosophie) -- UCL, 202

Troisième molaire inférieure incluse et ectopique au niveau de l’incisure sigmoïdienne mandibulaire: revue illustrée de la littérature et rapport de cas.

Impacted and ectopic lower third molars located in the sigmoid notch are very rare in clinical practice. Their etiology remains uncertain, although disturbances in the dental eruption process or consequences of trauma are suspected. Most cases described in the literature present various symptoms and require surgical management. The objective of this work is to conduct a literature review on impacted and ectopic lower third molars in the sigmoid notch region, to present a new clinical case illustrated by cone beam computed tomography (CBCT), and to establish possible management strategies, exploring the indications for surgical intervention according to the available literature

Invitation au débat mathématique, et à sa pratique dans les classes du primaire, secondaire et supérieur

Et si on incitait les élèves à débattre entre eux de situations mathématiques ? Dans un monde où l’esprit critique et l’autonomie de pensée sont essentiels, cet ouvrage invite à développer une culture du débat mathématique dans les classes. À partir d’une question mathématique, les élèves sont amenés à communiquer leurs idées, écouter celles des autres, argumenter et prendre du recul sur leurs raisonnements. Ce dispositif les place dans une posture active face aux apprentissages tout en promouvant le développement de compétences citoyennes au cours de mathématiques. Invitation au débat mathématique propose aux acteurs de l’enseignement des outils concrets pour intégrer cette pratique dans les classes, de la fin du primaire au supérieur. Il offre à la fois un guide synthétique pour la mise en oeuvre de débats et un recueil de 50 énoncés commentés destinés à provoquer le débat avec des élèves de tous âges. Les réflexions et analyses sont abondamment illustrées d’exemples, de témoignages d’enseignants et d’échos des classes. Que la pratique des débats mathématiques vous soit encore inconnue ou déjà familière, cet ouvrage nourrira votre réflexion au service d’un objectif fondamental : que les élèves pensent les mathématiques par eux-mêmes

If it ain’t broke, don’t fix it? Ten improvements for the upcoming tenth anniversary of the General Data Protection Regulation

As the General Data Protection Regulation (GDPR) approaches its tenth anniversary, the European legislator is considering reforms thereto. This article offers a set of research-based suggestions for how such reforms could look like, based on two assumptions. First, that the GDPR is overall a solid piece of legislation that upholds the enduring objectives and principles of data protection law. Second, that any improvement cannot compromise the level of protection of fundamental rights currently offered. To this end, ten scholars from across Europe were invited to choose a provision of the GDPR and write about what works well, what does not, and why, as well as to suggest a solution for a concrete amendment of the text. The resulting wish-list discussing ten provisions (i.e., those concerning conditions for consent, children’s consent, automated decision-making, data protection by design, data security, data protection impact assessment, prior consultation, derogations for data transfers, dispute resolution by the European Data Protection Board, representation of data subjects and processing for scientific purposes) is necessarily random and far from exhaustive. However, it lays the groundwork for a constructive debate, and we invite others to build on the list with their own proposals