Biology, Medicine, & Natural Product Chemistry (E-Journal - Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity)
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108 research outputs found
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A Simple and Practical Method for Rat Epididymal Sperm Count (Rattus norvegicus)
Sperm sample from epididymal source can be determined its number using minimal amount of equipment. These method will aid researcher and practitioner in sperm quality analysis to determined sperm number rapidly and practically
The Antidepressant Effects of (Arcangelisia flava (l.) Merr) Water-Soluble Extract in Balb-C Mice Reviewed from Immobility Time by Forced
This study was conducted to examine / determine the antidepressant effects of (Arcangelisiaflava L.) on immobility time of the white male mice strain Balb-c by the forced swim test method. The method of research using laboratory animals such as 25 micewas divided into 5 groups. As a negative control group was only given distilled water ad libitum. Amitryptiline was used as the positive control group; the experiment group was a water-soluble extract of A.flava by multiple doses. The results showed that the best antidepressant effects were312 mg/kgBW ; it had a minimum of immobility time compared with the other groups
Ecopharmacognosy: Exploring The Chemical And Biological Potential Of Nature For Human Health
“Why didn’t they develop natural product drugs in a sustainable manner at the beginning of this century?â€Â In 2035, when about 10.0 billion will inhabit Earth, will this be our legacy as the world contemplates the costs and availability of synthetic and gene-based products for primary health care? Acknowledging the recent history of the relationship between humankind and the Earth, it is essential that the health care issues being left for our descendants be considered in terms of resources. For most people in the world, there are two vast health care “gapsâ€, access to quality drugs and the development of drugs for major global and local diseases. Consequently for all of these people, plants, in their various forms, remain a primary source of health care. In the developed countries, natural products derived from plants assume a relatively minor role in health care, as prescription and over-the-counter products, even with the widespread use of phytotherapeutical preparations. Significantly, pharmaceutical companies have retrenched substantially in their disease areas of focus. These research areas do not include the prevalent diseases of the middle- and lower-income countries, and important diseases of the developed world, such as drug resistance. What then is the vision for natural product research to maintain the choices of drug discovery and pharmaceutical development for future generations? In this discussion some facets of how natural products must be involved globally, in a sustainable manner, for improving health care will be examined within the framework of the new term “ecopharmacognosyâ€, which invokes sustainability as the basis for research on biologically active natural products. Access to the biome, the acquisition, analysis and dissemination of plant knowledge, natural product structure diversification, biotechnology development, strategies for natural product drug discovery, and aspects of multitarget therapy and synergy research will be discussed. Options for the future will be presented which may be significant as countries decide how to develop approaches to relieve their own disease burden, and the needs of their population for improved access to medicinal agents
Larvicidal Activity of The Mixture of Cashew Nut Shell Liquid (CNSL) and Aqueous Extract of Sapindus rarak DC Against Larvae of Culex quinquefasciatus
The aim of this study was to evaluate the larvicidal activity of Cashew Nut Shell Liquid (CNSL) against the Culex quinque fasciatus in larval stage. The CNSL was diluted in water by addition of aqueous extract of Sapindus rarak DC to increase its solubility. Larvae were exposed to varying concentrations of that mixture. The larvae mortality was observed after 24 h exposure. LC50 and LC90 value by extrapolation were 20,52 ppm and 55,41 ppm respectively. CNSL were specified by characterizing its physico-chemical properties and anacardic acid as marker compound by High Performance Chromatography (HPLC). The results were the mixture of Cashew Nut Shell Liquid (CNSL) and Aquous extract of Sapindus rarak DC had larvicidal activity against Cx. Quinque-fasciatus and further investigations were needed to identify the fatty acid derivative as active compound of CNSL which responsible for larvicidal activity
Identification Of Migratory Birds And Their Spesific Characteristics Of Habitat In The Salt Water Lake Of Gili Meno, North Lombok Distric
The aim of this research was to identify the species of migratory birds in the ecosystem of salt water lake of Gili Meno and their specific characteristics of habitat. Data collection for birds, mangrove and fish species has been carried out in September and October 2013. In this study, a Shannon-Wiener Diversity Index and Importance Value Index (IVI) of mangrove vegetation were calculated to identify carrying capacity of mangrove population in the form of specific habitat in salt water lake of Gili Meno. This research has identified 17 species of birds which are divided into 5 families: Scolopacidae, Charadriidae, Ardeidae, Meropidae and Alcedinidae. Moreover, 3 species of mangrove were discovered that are A. marina, A. lanata and E. Agallocha, as well as one species of fish (Mujair fish/O. mossambicus). N. Nycticorax and B. Striatus were well-known to have higher population than other bird species. The Diversity Index showed that mangrove vegetation in the ecosystem of salt water lake of Gili Meno has a low species diversity (0.565). This is due to higher dominance of one species than the others. What is more, the IVI of A. marina demonstrated a fairly significant value compared to that of other species (189,01). Mangrove vegetation which surrounds the ecosystem of salt water lake of Gili Meno has formed a unique habitat and and an ideal stopover site for migratory birds. The ecosystem not only provides shelters from predators but also supplies for various abundant feeding sources. The lake it self is rather shallow and muddy around the shore which gives advantages for the migratory birds to obtain plenty small fish from the lake