1,999,987 research outputs found
Equi-energy sampler with applications in statistical inference and statistical mechanics
We introduce a new sampling algorithm, the equi-energy sampler, for efficient
statistical sampling and estimation. Complementary to the widely used
temperature-domain methods, the equi-energy sampler, utilizing the
temperature--energy duality, targets the energy directly. The focus on the
energy function not only facilitates efficient sampling, but also provides a
powerful means for statistical estimation, for example, the calculation of the
density of states and microcanonical averages in statistical mechanics. The
equi-energy sampler is applied to a variety of problems, including exponential
regression in statistics, motif sampling in computational biology and protein
folding in biophysics.Comment: This paper discussed in: [math.ST/0611217], [math.ST/0611219],
[math.ST/0611221], [math.ST/0611222]. Rejoinder in [math.ST/0611224].
Published at http://dx.doi.org/10.1214/009053606000000515 in the Annals of
Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical
Statistics (http://www.imstat.org
Statistical methods of SNP data analysis with applications
Various statistical methods important for genetic analysis are considered and
developed. Namely, we concentrate on the multifactor dimensionality reduction,
logic regression, random forests and stochastic gradient boosting. These
methods and their new modifications, e.g., the MDR method with "independent
rule", are used to study the risk of complex diseases such as cardiovascular
ones. The roles of certain combinations of single nucleotide polymorphisms and
external risk factors are examined. To perform the data analysis concerning the
ischemic heart disease and myocardial infarction the supercomputer SKIF
"Chebyshev" of the Lomonosov Moscow State University was employed
On applications of Orlicz Spaces to Statistical Physics
We present a new rigorous approach based on Orlicz spaces for the description
of the statistics of large regular statistical systems, both classical and
quantum. This approach has the advantage that statistical mechanics is much
better settled. In particular, a new kind of renormalization leading to states
having a well defined entropy function is presented.Comment: 20 page
- …