A Novel Approach of Virotherapy Based Hsf-1 Shrna in Cancer Eradication

Cancer is the second leading cause of death worldwide with continues rise mortality rate. Current cancer treatment modalities are still ineffective and associated with many side effects leading to robust research to find new specific target therapy. Heat shock factor (HSF)-1 is heat shock response mediator protein and act as transcription factor for HSP encoding gene. Many cancers have up-regulated HSP as a result of increase HSF-1 expression. Interestingly, inhibition of HSF-1 has no effect to normal cell, indicating HSF-1 as promises target therapy. RNAi is potential mechanism to block and down regulate HSF-1 which will affect many cellular processes in cancer cell. Combining RNAi base treatment with oncolityc viruses will boost the therapeutic effect of this novel treatment. Despite its potency, this modality still need further research in order to evaluate its efficacy and optimal doses to gain optimal result

A novel approach to Acoustic Echo cancellation

In this paper a novel approach to single microphone Acoustic Echo cancellation (AEC) is presented. This approach performs AEC by employing techniques developed for monaural sound source separation. It is shown that the AEC problem can be cast in a monaural sound source separation framework and through this framework significant echo suppression can be achieved. The new approach is evaluated through experiments on simulated data

A novel approach to Acoustic Echo cancellation

In this paper a novel approach to single microphone Acoustic Echo cancellation (AEC) is presented. This approach performs AEC by employing techniques developed for monaural sound source separation. It is shown that the AEC problem can be cast in a monaural sound source separation framework and through this framework significant echo suppression can be achieved. The new approach is evaluated through experiments on simulated data

A novel approach to CO2 capture in Fluid Catalytic Cracking-Chemical Looping Combustion

Oil refineries collectively account for about 4–6% of global CO2 emissions and Fluid Catalytic Cracking (FCC) units are responsible for roughly 25% of these. Although post-combustion and oxy-combustion have been suggested to capture CO2 released from the regenerator of FCC units, Chemical Looping Combustion (CLC) is also a potential approach. In this study, the applicability of CLC for FCC units has been explored. A refinery FCC catalyst (equilibrium catalyst-ECat) was mixed mechanically with reduced oxygen carriers; Cu, Cu2O, CoO, and Mn3O4. To identify any detrimental effects of the reduced oxygen carriers on cracking, the catalyst formulations were tested for n-hexadecane cracking using ASTM D3907-13, the standard FCC microactivity test (MAT). To investigate the combustion reactivity of coke with physically mixed oxidised oxygen carriers, CuO, Co3O4 and Mn2O3, TGA tests were conducted on a low volatile semi-anthracite Welsh coal, which has a similar elemental composition to actual FCC coke, with various oxygen carrier to coke ratios over the temperature range 750–900 °C.The results demonstrated that, whereas Cu was detrimental for cracking n-hexadecane with the ECat, Cu2O, CoO, and Mn3O4 have no significant effects on gas, liquid and coke yields, and product selectivity. Complete combustion of the model coke was achieved with CuO, Co3O4 and Mn2O3, once the stoichiometric ratio of oxygen carrier/coke was higher than 1.0 and sufficient time had been provided. These results indicate that the proposed CLC-FCC concept has promise as a new approach to CO2 capture in FCC

A Novel Approach for Compressing Surveillance System Videos

The surveillance systems are expected to record the videos in 24/7 and obviously it requires a huge storage space. Even though the hard disks are cheaper today, the number of CCTV cameras is also vertically increasing in order to boost up security. The video compression techniques is the only better option to reduce required the storage space; however, the existing video compression techniques are not adequate at all for the modern digital surveillance system monitoring as they require huge video streams. In this paper, a novel video compression technique is presented with a critical analysis of the experimental results

A Novel Approach for Workflow Scheduling in Hybrid Cloud with Dynamic Datacenter

Work process is used to speak to variety of use which requires huge data figuring and limit. To vanquish this need of data computation and limit dispersed processing has created as one of the best responses for on asks for resource provider. Nevertheless, on occasion the benefits open to us may not be satisfactory, so the need develops to gather more sources from various fogs. This is done by using the Hybrid cloud. Half and half cloud is mix of open and private cloud. The private cloud is guaranteed by the customer consequently there are no extra charges for using the benefits available in it, however open cloud is controlled by others so we have to pay for the using the advantage as indicated by the businesses. The USAge of the cream cloud offers adaptability to the customer. While using the half breed cloud, two most basic inquiries rises. The first is the best approach to segment the work procedure. In addition, the second one is the thing that benefit we need to get from individuals as a rule cloud so it can meet our essential inside the foreordained due date. The changed booking organization work handle for hybrid cloud give the less make span for the DAG than the main figuring and give us the best resources that we need to secure from open cloud to have enough planning vitality to arrange the work procedure inside given due date. We have gone through with two different approaches after scheduling has been performed to check the successful transaction between dynamic and static data center. We contemplated a hybrid approach which will reduce the complexity of the network but at the same time it also perform successful transaction between dynamic datacenters .Each time the transaction has been performed between different centers or clusters the consequences are successful

A Novel Approach for Eye Tracking using Driver Fatigue Monitoring

System describes a real-time online trial product driver-fatigue monitor or driver tiredness is captured. It means to capture the current state or mode of tiredness of driver whether the driver is in sleeping state or in wakening state. It uses remotely located charge-coupled-device cameras able to with active infrared illumination to acquire video images of the driver. Various cues that typically stated the level of attentiveness of a person that how an person is attentive are removed or take out in real time and systematic combined to infer the tiredness level of the driver. The some cues employed stated eyelid movement, steady movement, head movement, and facial expression. This is developed to model human fatigue and to know about fatigue based on the visual cues obtained. The simultaneous use of multiple optical cues and their methodical combination yields a much more robust and accurate fatigue categorization than using a single visual cue. This system was valid as real-life fatigue conditions with human subjects of different cultural backgrounds, genders, and ages as with or without glasses, and under different illumination conditions. It was found to be sensibly robust, reliable, and accurate in fatigue categorization

A novel approach for the consideration of plastic material behavior in thermodynamic topology optimization

In order to find optimal structures for realistic applications, it is essential to include the real material behavior in the optimization process. For this purpose, this research focuses on thermodynamic topology optimization accounting for plasticity for which a surrogate material model is developed. Characteristically, the stress/strain diagram resulting from physical loading and unloading shows a hysteresis for classical plasticity models. Our material model takes only the physical loading during the optimization process into account. To this end, during a virtual unloading in the optimization process, the dissipation of energy is suppressed which yields the same elasto/plastic deformation state as for physical loading. By using this novel material model, optimized structures can be computed without resourceful classical path-dependent plasticity computation

A Novel Approach for Code Clone Detection Using Hybrid Technique

Code clones have been studied for long, and there is strong evidence that they are a major source of software faults. The copying of code has been studied within software engineering mostly in the area of clone analysis. Software clones are regions of source code which are highly similar; these regions of similarity are called clones, clone classes, or clone pairs In this paper a hybrid approach using metric based technique with the combination of text based technique for detection and reporting of clones is proposed. The Proposed work is divided into two stages selection of potential clones and comparing of potential clones using textual comparison. The proposed technique detects exact clones on the basis of metric match and then by text match