Time-resolved, multi-color photometry and spectroscopy of Virgo 4 (OU Vir): a high orbital inclination, short orbital period dwarf nova

We present multi-color photometry and time resolved spectroscopy of OU Vir. The analysis of the quiescent light curve shows that OU Vir is characterized by i) strong cycle-to-cycle brightness variations, and ii) hot spot modulated light curve with grazing eclipse of the impact region. Colors are derived both in- and out- of eclipse. The time-resolved spectroscopy allows us to produce the radial velocity curve from the H$\alpha$ accretion disk emission line which possibly reveals only weak evidence for hot spot line emission. The hot spot is believed to be a turbulent optically thick region, producing mostly continuum emission.Comment: 8 pages (including figures), 7 figures. To Be published in A&

Study of second breakdown in power transistors using infrared techniques

Infrared thermal maps pinpoint exact location where second breakdown will occur before phenomenon happens and before physical damage develops at hot spot. Crystal structure analysis at that point determines cause of fault. Absolute power of radiation emitted from hot spot is direct indication of voltage level at which second breakdown occur

Modification of the pattern informatics method for forecasting large earthquake events using complex eigenvectors

Recent studies have shown that real-valued principal component analysis can be applied to earthquake fault systems for forecasting and prediction. In addition, theoretical analysis indicates that earthquake stresses may obey a wave-like equation, having solutions with inverse frequencies for a given fault similar to those that characterize the time intervals between the largest events on the fault. It is therefore desirable to apply complex principal component analysis to develop earthquake forecast algorithms. In this paper we modify the Pattern Informatics method of earthquake forecasting to take advantage of the wave-like properties of seismic stresses and utilize the Hilbert transform to create complex eigenvectors out of measured time series. We show that Pattern Informatics analyses using complex eigenvectors create short-term forecast hot-spot maps that differ from hot-spot maps created using only real-valued data and suggest methods of analyzing the differences and calculating the information gain.Comment: 13 pages, 1 figure. Submitted to Tectonophysics on 30 August 200

Evolution of a localized thermal explosion in a reactive gas

Experimental observations of ignition in premixed gaseous reactants indicate that perfectly homogeneous initiation is practically unrealizable. Instead, combustion first sets in, as a rule, at small, discrete sites where inherent inhomogeneities cause chemical activity to proceed preferentially and lead to localized explosions. Combustion waves propagating away from these hot spots or reaction centers eventually envelop the remaining bulk. This study examines the spatial structure and temporal evolution of a hot spot for a model involving Arrhenius kinetics. The hot spot, characterized by peaks in pressure and temperature with little diminution in local density, is shown to have one of two possible self-similar structures. The analysis employs a combination of asymptotics and numerics, and terminates when pressure and temperature in the explosion have peaked

Hot-spot analysis for drug discovery targeting protein-protein interactions

Introduction: Protein-protein interactions are important for biological processes and pathological situations, and are attractive targets for drug discovery. However, rational drug design targeting protein-protein interactions is still highly challenging. Hot-spot residues are seen as the best option to target such interactions, but their identification requires detailed structural and energetic characterization, which is only available for a tiny fraction of protein interactions. Areas covered: In this review, the authors cover a variety of computational methods that have been reported for the energetic analysis of protein-protein interfaces in search of hot-spots, and the structural modeling of protein-protein complexes by docking. This can help to rationalize the discovery of small-molecule inhibitors of protein-protein interfaces of therapeutic interest. Computational analysis and docking can help to locate the interface, molecular dynamics can be used to find suitable cavities, and hot-spot predictions can focus the search for inhibitors of protein-protein interactions. Expert opinion: A major difficulty for applying rational drug design methods to protein-protein interactions is that in the majority of cases the complex structure is not available. Fortunately, computational docking can complement experimental data. An interesting aspect to explore in the future is the integration of these strategies for targeting PPIs with large-scale mutational analysis.This work has been funded by grants BIO2016-79930-R and SEV-2015-0493 from the Spanish Ministry of Economy, Industry and Competitiveness, and grant EFA086/15 from EU Interreg V POCTEFA. M Rosell is supported by an FPI fellowship from the Severo Ochoa program. The authors are grateful for the support of the the Joint BSC-CRG-IRB Programme in Computational Biology.Peer ReviewedPostprint (author's final draft

Building of the Amsterdam-Saint Paul plateau: A 10 Myr history of a ridge-hot spot interaction and variations in the strength of the hot spot source

International audienceThe Amsterdam-Saint Paul plateau results from a 10 Myr interaction between the South East Indian Ridge and the Amsterdam-Saint Paul hot spot. During this period of time, the structure of the plateau changed as a consequence of changes in both the ridge-hot spot relative distance and in the strength of the hot spot source. The joint analysis of gravity-derived crust thickness and bathymetry reveals that the plateau started to form at ~10 Ma by an increase of the crustal production at the ridge axis, due to the nearby hot spot. This phase, which lasted 3-4 Myr, corresponds to a period of a strong hot spot source, maybe due to a high temperature or material flux, and decreasing ridge-hot spot distance. A second phase, between ~6 and ~3 Ma, corresponds to a decrease in the ridge crustal production. During this period, the hot spot center was close to the ridge axis and this reduced magmatic activity suggests a weak hot spot source. At ~3 Ma, the ridge was located approximately above the hot spot center. An increase in the hot spot source strength then resulted in the building of the shallower part of the plateau. The variations of the melt production at the ridge axis through time resulted in variations in crustal thickness but also in changes in the ridge morphology. The two periods of increased melt production correspond to smooth ridge morphology, characterized by axial highs, while the intermediate period corresponds to a rougher, rift-valley morphology. These variations reveal changes in axial thermal structure due to higher melting production rates and temperatures

Iron lines from transient and persisting hot spots on AGN accretion disks

[abridged] We model the X-ray reprocessing from a strong co-rotating flare above an accretion disk in active galactic nuclei. We explore the horizontal structure and evolution of the underlying hot spot. To obtain the spectral evolution seen by a distant observer, we apply a general relativity ray-tracing technique. We concentrate on the energy band around the iron K-line, where the relativistic effects are most pronounced. Persistent flares lasting for a significant fraction of the orbital time scale and short, transient flares are considered. In our time-resolved analysis, the spectra recorded by a distant observer depend on the position of the flare/spot with respect to the central black hole. If the flare duration significantly exceeds the light travel time across the spot, then the spot horizontal stratification is unimportant. On the other hand, if the flare duration is comparable to the light travel time across the spot radius, the lightcurves exhibit a typical asymmetry in their time profiles. The sequence of dynamical spectra proceeds from more strongly to less strongly ionized re-emission. At all locations within the spot the spectral intensity increases towards edge-on emission angles, revealing the limb brightening effect. Future X-ray observatories with significantly larger effective collecting areas will enable to spectroscopically map out the azimuthal irradiation structure of the accretion disk and to localize persistent flares. If the hot spot is not located too close to the marginally stable orbit of the black hole, it will be possible to probe the reflecting medium via the sub-structure of the iron K-line. Indications for transient flares will only be obtained from analyzing the observed lightcurves on the gravitational time scale of the accreting supermassive black hole.Comment: 15 pages, 8 figures, accepted by Astronomy & Astrophysic