Effectiveness of Seasonal Malaria Chemoprevention in children under 10 years of age in Senegal: a stepped-wedge cluster-randomized trial

This study was done to determine the effectiveness of Seasonal Malaria Chemoprevention in Senegalese children up to 10 years of age using a stepped-wedge design. Outcomes included mortality, malaria cases treated as outpatients, severe malaria, and the prevalence of parasitaemia and anaemia, and adverse drug reactions. 54 health posts were randomized. 9 started implementation of SMC in 2008, 18 in 2009, and a further 18 in 2010, with 9 remaining as controls. In the first year of implementation SMC was delivered to children aged 3-59 months, the age range was then extended for the latter two years of the study to include children up to 10 years of age

Friendship Bench trial: lay worker training in problem-solving therapy to reduce symptoms of common mental disorders

The Friendship Bench trial is a cluster-randomised trial of the effect of problem-solving therapy training for lay workers on symptoms of common mental disorders among clinic attenders in Harare, Zimbabwe. This dataset enables replication of analysis for a paper on suicidal ideation, but has undergone anonymisation process to protect study participants. 12 primary care clinics in Harare were randomised 1:1 to intervention or control. In each clinic, 24 participants were enrolled who were: visiting the clinic (either for their own health needs or accompanying someone else); aged 18 or over; living locally; and screened positive for common mental disorder symptoms. Outcomes were measured after 6 months. 86% of participants were women, 42% were HIV positive and 91% completed follow-up

Baseline and primary data for the partner-provided HIV self-testing and linkage (PASTAL) adaptive multi-arm multi-stage cluster randomized trial in Blantyre, Malawi

Dataset containing details of 2,349 pregnant women accessing antenatal care in three primary health centres in urban Blantyre, Malawi who gave informed consent to participate in an adaptive multi-arm multi-stage cluster randomized trial. The unit of randomization was the antenatal care (ANC) clinic day. On a given ANC day, women could receive standard of care (SOC) of receiving just an invitation letter to deliver to their male partner who was absent at this ANC visit. Or, the women could receive SOC plus two oral self-test kits alone or in combination with a guaranteed financial incentive of $3 or$10 conditional on clinic attendance following self-testing for HIV care or prevention. Two other arms offered a lottery-based incentive with 10% chance of winning $30 to male partners achieving the primary outcome, or a phone call reminder to the male partner immediately following collection of kits by the woman repeated after five days. The dataset contains variables on baseline data for the women and their male partners as reported by the woman as well as data underlying the trial outcomes by arm. Recruitment and follow-up were completed between 8 August 2016 and 30 June 2017

Data for Thinking Healthy Programme Pakistan trial (THPP-Pakistan)

An anonymised dataset of 570 women (one row per woman) who gave informed consent to participate in a cluster randomised, parallel, superiority, controlled trial in Rawalpindi, Pakistan in 2014-2017. The intervention was an adapted version of the Thinking Healthy Programme, delivered by peers; the control was enhanced usual care. Further details are available in the published protocol and paper. The dataset contains records of variables on stratified randomisation and clusters, socio-demographic information, depression and related outcomes, and therapy adherence. Visits occurred at baseline, and 3 and 6 months post-natal

IDEAS project - Data Informed Platform for Health feasibility study in Uttar Pradesh

The IDEAS project sought to improve the health and survival of mothers and babies through generating evidence to inform policy and practice. This data collection contains topic guides and other research tools used to assess the feasibility of introducing a Data Informed Platform for Health (DIPH), in order to bring together key data from the public and private health sector on inputs and processes that may influence maternal and newborn health. The DIPH was intended to promote the use of local data for decision-making and priority setting at local health administration level, and for programme appraisal and comparison at regional and zonal level

Delivering the English immunisation programme – survey response dataset

An anonymised dataset containing results of an online survey completed by 278 health practitioners in 2016. The online survey sought to assess how the national immunisation programme (specifically Section 7a immunisation programmes) was being delivered across different regions of England. The dataset contains variables on the respondent’s professional background, individual and organisational responsibility for immunisation, levels of co-operation between partner organisations to manage and deliver the immunisation programme, and what is being done to monitor and improve the performance of immunisation services (e.g. quality and uptake).The survey forms part of a long-term analysis of how the national immunisation programme is managed and delivered in the post-April 2013 health system. It is was conducted by the ‘Health Protection Research Unit (HPRU) in Immunisation’, which includes researchers from the London School of Hygiene & Tropical Medicine (LSHTM) and Public Health England. The unit is funded by the National Institute of Health Research

LSHTM Research Data Management Summary Guides

A set of one-page guides to good practice on various data management-related topics, including data management plans, data encryption and data sharing. These guides are CC-licensed and can be re-purposed by other institutions. Editable versions of the guides can be found in the ZIP archive

EN-BIRTH Data Collector Training - Handbook and Manual

The EN-BIRTH study aims to validate selected newborn and maternal indicators for routine facility-based tracking of coverage and quality of care for use at district, national and global levels. The item contains the EN-BIRTH_Trainer's Manual (14 June 2017) and EN-BIRTH_Training Handbook (23 May 2017)

An online survey of adults with cystic fibrosis: accessing and using life expectancy information

A spreadsheet containing a subset of the original data from all respondents (n=85) from an online questionnaire entitled "Online survey to gain understanding of what people with cystic fibrosis aged 16+ would like to learn about their life expectancy and other outcomes". The survey was conducted in July 2016. Responses to all multiple choice questions are included. Free text responses have been removed in accordance with information provided to the respondents. Ages have been categorised. The data do not contain any identifying information

Mortality predictor score in hospitalised patients HIV-associated TB in Africa dataset

This dataset contains details of hospital patients with HIV-associated tuberculosis in sub-Saharan Africa from the STAMP clinical trial. It was generated to derive predictor score for mortality including urine lipoarabinomannan detection. Variables include: age, sex, weight, living status, number of day in follow-up, ART treatment, WHO danger sign, Haemoglobin level, ability to walk, and urine LAM positivity