Strategic assessment of the magnitude and impacts of sand mining in Poyang Lake, China

Planning for the extraction of aggregates is typically dealt with at a case to case basis, without assessing environmental impacts strategically. In this study we assess the impact of sand mining in Poyang Lake, where dredging began in 2001 after sand mining in the Yangtze River had been banned. In April 2008 concern over the impact on the biodiversity led to a ban on sand mining in Poyang Lake until further plans could be developed. Planning will require consideration of both sand extraction in relation to available sediment resources and also environmental impacts within the context of future demand for sand in the lower Yangtze Valley. We used pairs of near-infrared (NIR) Aster satellite imagery to estimate the number of vessels leaving the lake. Based on this we calculated a rate of sand extraction of 236 million m3 year-1 in 2005–2006. This corresponds to 9% of the total Chinese demand for sand. It qualifies Poyang Lake as probably the largest sand mining operation in the world. It also indicates that sand extraction currently dominates the sediment balance of the lower Yangtze River. A positive relation between demand for sand and GDP, revealed by historic data from the USA, suggests that the current per capita demand for sand in China might increase in the near future from 2 to 4 m3 year-1. We review various environmental impacts and question whether it will be possible to preserve the rich biodiversity of the lake, while continuing at the same time satisfying the increasing Chinese demand for sand. Finally we review alternative options for sand mining, in order to relieve the pressure from the Poyang Lake ecosyste

A Rare Complication of a Vaginal Breech Delivery

Rectal lesions without anal sphincter trauma in childbirth are only sporadically described in literature. We describe the case of a 29-year-old primigravida who delivered a child in frank breech presentation. During the second stage of labour a foot presented transanally through a rectal laceration with intact anal sphincters. The laceration was repaired immediately after delivery in theatre. Follow-up visits showed a properly cured laceration and no complaints of incontinence or foul discharge

Long-Ranged Orientational Order in Dipolar Fluids

Recently Groh and Dietrich claimed the thermodynamic state of a dipolar fluid depends on the shape of the fluid's container. For example, a homogeneous fluid in a short fat container would phase separate when transferred to a tall skinny container of identical volume and temperature. Their calculation thus lacks a thermodynamic limit. We show that removal of demagnetizing fields restores the true, shape independent, thermodynamic limit. As a consequence, spontaneously magnetized liquids display inhomogeneous magnetization textures.Comment: 3 pages, LaTex, no figures. Submitted as comment to PRL, May 199

Integrating care for people with depression: developments in the Netherlands

Introduction: In this article we describe the history and present state of integrated care for people with depression in the Netherlands. The central question is: what are the developments in integrated care for people with depression in the Netherlands?Methods: We describe these developments from the role of an observer, and make use of several sources: important Dutch policy documents and research documents, our own national survey carried out in 2007, a number of reports and project descriptions and searches in PubMed and Google. Also key people were contacted to supply additional information.Results: In the Netherlands two separate phases can be distinguished within integrated care for people with depression. From the beginning of the 1990s, specialized secondary Mental Health Care (MHC) began to develop care programmes, including programmes for people with depression. The implementation of these care programmes has taken years. Mass usage of care programmes only went ahead once the large-scale mergers between ambulatory and clinical MHC organizations around 2000 had taken effect. An analysis of these programmes shows, that they did not lead to integration with primary care. This changed in the second phase from around 2000. Then attention was directed more towards strengthening the GP within the treatment of depression, collaboration between primary and specialized care and the development of collective integrated care packages.Discussion: We relate these developments to projects in other countries and discuss the scientific basis by using evidence of international literature reviews and metastudies. Some general recommendations are given about functional costing, the physical presence of MHC specialists in the primary care sector and the use of a common national standard for both primary care and specialized MHC

DFT-D2 simulations of water adsorption and dissociation on the low-index surfaces of mackinawite (FeS)

The adsorption and dissociation of water on mackinawite (layered FeS) surfaces were studied using dispersion-corrected density functional theory (DFT-D2) calculations. The catalytically active sites for H2O and its dissociated products on the FeS {001}, {011}, {100}, and {111} surfaces were determined, and the reaction energetics and kinetics of water dissociation were calculated using the climbing image nudged elastic band technique. Water and its dissociation products are shown to adsorb more strongly onto the least stable FeS{111} surface, which presents low-coordinated cations in the surface, and weakest onto the most stable FeS{001} surface. The adsorption energies decrease in the order FeS{111} > FeS{100} > FeS{011} > FeS{001}. Consistent with the superior reactivity of the FeS{111} surface towards water and its dissociation products, our calculated thermochemical energies and activation barriers suggest that the water dissociation reaction will take place preferentially on the FeS nanoparticle surface with the {111} orientation. These findings improve our understanding of how the different FeS surface structures and the relative stabilities dictate their reactivity towards water adsorption and dissociation

HID-1 controls formation of large dense core vesicles by influencing cargo sorting and trans-Golgi network acidification

Large dense core vesicles (LDCVs) mediate the regulated release of neuropeptides and peptide hormones. They form at the trans-Golgi network (TGN), where their soluble content aggregates to form a dense core, but the mechanisms controlling biogenesis are still not completely understood. Recent studies have implicated the peripheral membrane protein HID-1 in neuropeptide sorting and insulin secretion. Using CRISPR/Cas9, we generated HID-1 KO rat neuroendocrine cells, and we show that the absence of HID-1 results in specific defects in peptide hormone and monoamine storage and regulated secretion. Loss of HID-1 causes a reduction in the number of LDCVs and affects their morphology and biochemical properties, due to impaired cargo sorting and dense core formation. HID-1 KO cells also exhibit defects in TGN acidification together with mislocalization of the Golgi-enriched vacuolar H+-ATPase subunit isoform a2. We propose that HID-1 influences early steps in LDCV formation by controlling dense core formation at the TGN.</jats:p

Field-induced domain wall propagation velocity in magnetic nanowires

A thory of field-induced domain wall (DW) propagation is developed. The theory not only explains why a DW in a defect-free nanowire must propagate at a finite velocity, but also provides a proper definition of DW propagation velocity. This definition, valid for an arbitrary DW structure, allows one to compute the instantaneous DW velocity in a meaningful way even when the DW is not moving as a rigid body. A new velocity-field formula beyond the Walker breakdown field, which is in excellent agreement with both experiments and numerical simulations, is derived