Gap Opening in Protoplanetary Disks: Gas Dynamics from Global Non-ideal MHD Simulations with Consistent Thermochemistry

Recent high angular resolution ALMA observations have revealed numerous gaps in protoplanetary disks. A popular interpretation has been that planets open them. Most previous investigations of planet gap-opening have concentrated on viscous disks. Here, we carry out 2D (axisymmetric) global simulations of gap opening by a planet in a wind-launching non-ideal MHD disk with consistent thermochemistry. We find a strong concentration of poloidal magnetic flux in the planet-opened gap, where the gas dynamics are magnetically dominated. The magnetic field also drives a fast (nearly sonic) meridional gas circulation in the denser disk regions near the inner and outer edges of the gap, which may be observable through high-resolution molecular line observations. The gap is more ionized than its denser surrounding regions, with a better magnetic field-matter coupling. In particular, it has a much higher abundance of molecular ion HCO$^+$, consistent with ALMA observations of the well-studied AS 209 protoplanetary disk that has prominent gaps and fast meridional motions reaching the local sound speed. Finally, we provide fitting formulae for the ambipolar and Ohmic diffusivities as a function of the disk local density, which can be used for future 3D simulations of planet gap-opening in non-ideal MHD disks where thermochemistry is too computationally expensive to evolve self-consistently with the magneto-hydrodynamics.Comment: 12 pages, 13 figures and 4 tables, submitted to MNRAS. For animated figures, see: https://www.youtube.com/watch?v=GvVPT-SOP6s&list=PLPqbg5l-CV-t-TUePtpv7VtqPL1PHP1U5&ab_channel=FloridaKey

2,2′-(Butane-1,4-di­yl)diisoquinolinium tetra­chloridozincate(II)

The crystal of the title compound, (C22H22N2)[ZnCl4], consists of 2,2′-(butane-1,4-di­yl)diisoquinolinium organic cations and [ZnCl4]2− complex anions. The cation is located across a twofold axis and the ZnII atom of the anion is located on the other twofold axis. The centroid–centroid distance between parallel pyridine rings of neighboring mol­ecules is 3.699 (3) Å, but the face-to-face separation of 3.601 (3) Å suggests there is no significant π–π stacking in the crystal structure

Effect of prodigiosin on the alleviation of the intestinal inflammation of weaned rats based on 1H-NMR spectroscopy study and biochemistry indexes

Weaning results in intestinal dysfunction, mucosal atrophy, transient anorexia, and intestinal barrier defects. In this study, the effect of prodigiosin (PG) on the intestinal inflammation of weaned rats was investigated by using 1 H-NMR spectroscopy and biochemistry indexes to regulate the intestinal metabolism. After administration for 14 days, the body mass of the PG group was increased by 1.29‑ and 1.26-fold compared with those of the control and alcohol groups, respectively, using a dose of 200 μg PG·kg-1 body weight per day. PG increased organic acid content and decreased moisture, pH values, and free ammonia in feces. In addition, PG alleviated the intestinal inflammation of weaned rats. The analysis of 1 H-NMR signal peak attribution and the model validation of metabolic data of feces contents showed that PG significantly affected the metabolism of small molecular compounds in the intestinal tract of weaned rats. This study presents the promising alternative of using PG to alleviate intestinal inflammation effectively in the intestinal tract of weaned rats

A new mapping method for quantitative trait loci of silkworm

<p>Abstract</p> <p>Background</p> <p>Silkworm is the basis of sericultural industry and the model organism in insect genetics study. Mapping quantitative trait loci (QTLs) underlying economically important traits of silkworm is of high significance for promoting the silkworm molecular breeding and advancing our knowledge on genetic architecture of the Lepidoptera. Yet, the currently used mapping methods are not well suitable for silkworm, because of ignoring the recombination difference in meiosis between two sexes.</p> <p>Results</p> <p>A mixed linear model including QTL main effects, epistatic effects, and QTL × sex interaction effects was proposed for mapping QTLs in an F₂population of silkworm. The number and positions of QTLs were determined by <it>F</it>-test and model selection. The Markov chain Monte Carlo (MCMC) algorithm was employed to estimate and test genetic effects of QTLs and QTL × sex interaction effects. The effectiveness of the model and statistical method was validated by a series of simulations. The results indicate that when markers are distributed sparsely on chromosomes, our method will substantially improve estimation accuracy as compared to the normal chiasmate F₂model. We also found that a sample size of hundreds was sufficiently large to unbiasedly estimate all the four types of epistases (i.e., additive-additive, additive-dominance, dominance-additive, and dominance-dominance) when the paired QTLs reside on different chromosomes in silkworm.</p> <p>Conclusion</p> <p>The proposed method could accurately estimate not only the additive, dominance and digenic epistatic effects but also their interaction effects with sex, correcting the potential bias and precision loss in the current QTL mapping practice of silkworm and thus representing an important addition to the arsenal of QTL mapping tools.</p