An external potential dynamic study on the formation of interface in polydisperse polymer blends

The formation of interface from an initial sharp interface in polydisperse A/B blends is studied using the external potential dynamic method. The present model is a nonlocal coupling model as we take into account the correlation between segments in a single chain. The correlation is approximately expressed by Debye function and the diffusion dynamics are based on the Rouse chain model. The chain length distribution is described by the continuous Schulz distribution. Our numerical calculation indicates that the broadening of interface with respect to time obeys a power law at early times, and the power law indexes are the same for both monodisperse and polydisperse blend. The power law index is larger than that in the local coupling model. However there is not a unified scaling form of the broadening of the interface width if only the interfacial width at equilibrium is taken into account as the characteristic length of the system, because the correlation makes an extra characteristic length in the system, and the polydispersity is related to this length.Comment: 15 pages, 5 figure

Dimensional Analysis Theory and Molecular Dynamics Simulation of Polypropylene Melt Flow during Injection Molding Process

Flow marks are common surface defects that occur in injection-molded products. Their formation may be related to the flow process of the melt in the mold. Through dimensional analysis, we have discovered that the geometric shape of the flow field is controlled by specific dimensionless quantities. These quantities can be summarized as follows: geometric dimensionless quantities related to the shape of the mold, material dimensionless quantities related to the melt and mold materials, and physical dimensionless quantities related to the flow. When the geometric shape of the mold changes proportionally, with the melt and mold material fixed, and the initial temperature of the melt and mold fixed, the geometric shape of the flow field will be solely controlled by the Weissenberg number Wi. If Wi is kept constant, changing the injection speed, changing the relaxation time of the polypropylene melt, or scaling the mold will result in similar geometric shapes of the flow field. If the size of the mold is not changed, the geometric shape of the flow field will be the same. Since the dimensionless equation represents a similar system of all sizes, we verified the above conclusion through molecular dynamics simulations at a smaller scale. After further improvement of the micro simulation system, there is a possibility of visualizing the formation process of flow marks. This would greatly aid in the advancement of theory and the elimination of flow marks in production and experiments. This work also illustrates that the methodology of dimensional analysis plus molecular dynamics simulation may be applied to a wider range of other systems, scaling down large systems and thus significantly reducing their computational effort

Association analysis of stem rust resistance in U.S. winter wheat

Citation: Zhang D, Bowden RL, Yu J, Carver BF, Bai G (2014) Association Analysis of Stem Rust Resistance in U.S. Winter Wheat. PLoS ONE 9(7): e103747. https://doi.org/10.1371/journal.pone.0103747Stem rust has become a renewed threat to global wheat production after the emergence and spread of race TTKSK (also known as Ug99) and related races from Africa. To elucidate U.S. winter wheat resistance genes to stem rust, association mapping was conducted using a panel of 137 lines from cooperative U.S. winter wheat nurseries from 2008 and simple sequence repeat (SSR) and sequence tagged site (STS) markers across the wheat genome. Seedling infection types were evaluated in a greenhouse experiment using six U.S. stem rust races (QFCSC, QTHJC, RCRSC, RKQQC, TPMKC and TTTTF) and TTKSK, and adult plant responses to bulked U.S. races were evaluated in a field experiment. A linearization algorithm was used to convert the qualitative Stakman scale seedling infection types for quantitative analysis. Association mapping successfully detected six known stem rust seedling resistance genes in U.S. winter wheat lines with frequencies: Sr6 (12%), Sr24 (9%), Sr31 (15%), Sr36 (9%), Sr38 (19%), and Sr1RS[superscript Amigo] (8%). Adult plant resistance gene Sr2 was present in 4% of lines. SrTmp was postulated to be present in several hard winter wheat lines, but the frequency could not be accurately determined. Sr38 was the most prevalent Sr gene in both hard and soft winter wheat and was the most effective Sr gene in the adult plant field test. Resistance to TTKSK was associated with nine markers on chromosome 2B that were in linkage disequilibrium and all of the resistance was attributed to the Triticum timopheevii chromosome segment carrying Sr36. Potential novel rust resistance alleles were associated with markers Xwmc326-203 on 3BL, Xgwm160-195 and Xwmc313-225 on 4AL near Sr7, Xgwm495-182 on 4BL, Xwmc622-147 and Xgwm624-146 on 4DL, and Xgwm334-123 on 6AS near Sr8. Xwmc326-203 was associated with adult plant resistance to bulked U.S. races and Xgwm495-182 was associated with seedling resistance to TTKSK

Genome-wide association analysis on pre-harvest sprouting resistance and grain color in US winter wheat

Citation: Lin, M., Zhang, D. D., Liu, S. B., Zhang, G. R., Yu, J. M., Fritz, A. K., & Bai, G. H. (2016). Genome-wide association analysis on pre-harvest sprouting resistance and grain color in US winter wheat. Bmc Genomics, 17, 16. doi:10.1186/s12864-016-3148-6Background: Pre-harvest sprouting (PHS) in wheat can cause substantial reduction in grain yield and end-use quality. Grain color (GC) together with other components affect PHS resistance. Several quantitative trait loci (QTL) have been reported for PHS resistance, and two of them on chromosome 3AS (TaPHS1) and 4A have been cloned. Methods: To determine genetic architecture of PHS and GC and genetic relationships of the two traits, a genome-wide association study (GWAS) was conducted by evaluating a panel of 185 U.S. elite breeding lines and cultivars for sprouting rates of wheat spikes and GC in both greenhouse and field experiments. The panel was genotyped using the wheat 9K and 90K single nucleotide polymorphism (SNP) arrays. Results: Four QTL for GC on four chromosomes and 12 QTL for PHS resistance on 10 chromosomes were identified in at least two experiments. QTL for PHS resistance showed varied effects under different environments, and those on chromosomes 3AS, 3AL, 3B, 4AL and 7A were the more frequently identified QTL. The common QTL for GC and PHS resistance were identified on the long arms of the chromosome 3A and 3D. Conclusions: Wheat grain color is regulated by the three known genes on group 3 chromosomes and additional genes from other chromosomes. These grain color genes showed significant effects on PHS resistance in some environments. However, several other QTL that did not affect grain color also played a significant role on PHS resistance. Therefore, it is possible to breed PHS-resistant white wheat by pyramiding these non-color related QTL

BAVS: Bootstrapping Audio-Visual Segmentation by Integrating Foundation Knowledge

Given an audio-visual pair, audio-visual segmentation (AVS) aims to locate sounding sources by predicting pixel-wise maps. Previous methods assume that each sound component in an audio signal always has a visual counterpart in the image. However, this assumption overlooks that off-screen sounds and background noise often contaminate the audio recordings in real-world scenarios. They impose significant challenges on building a consistent semantic mapping between audio and visual signals for AVS models and thus impede precise sound localization. In this work, we propose a two-stage bootstrapping audio-visual segmentation framework by incorporating multi-modal foundation knowledge. In a nutshell, our BAVS is designed to eliminate the interference of background noise or off-screen sounds in segmentation by establishing the audio-visual correspondences in an explicit manner. In the first stage, we employ a segmentation model to localize potential sounding objects from visual data without being affected by contaminated audio signals. Meanwhile, we also utilize a foundation audio classification model to discern audio semantics. Considering the audio tags provided by the audio foundation model are noisy, associating object masks with audio tags is not trivial. Thus, in the second stage, we develop an audio-visual semantic integration strategy (AVIS) to localize the authentic-sounding objects. Here, we construct an audio-visual tree based on the hierarchical correspondence between sounds and object categories. We then examine the label concurrency between the localized objects and classified audio tags by tracing the audio-visual tree. With AVIS, we can effectively segment real-sounding objects. Extensive experiments demonstrate the superiority of our method on AVS datasets, particularly in scenarios involving background noise. Our project website is https://yenanliu.github.io/AVSS.github.io/

The thermal damaging process of diorite under microwave irradiation

Laboratory tests have been conducted to investigate the effects of thermal damage on diorite under microwave irradiation. The sample rocks were heated to high temperature range of 300 to 800 ℃ in a single-mode microwave furnace. The experimental results show that the rocks started to crack at 500 ℃ and completely disintegrated at 700 ℃. The intensities of quartz diffraction peaks were almost unchanged while the diffraction peak intensity of hornblende gradually decreased with temperature increasing. In addition, the chlorite diffraction peak disappeared at 500 ℃. The compressive strength of the sample decreased to 40% at 600 ℃ and it approached zero at 700 ℃. In this paper, the possible reasons for the thermal effects on the fracture of diorite were discussed, which can be related to water evaporation, thermal cracks and mismatch thermal expansion, and phase transition on quartz. The result indicates that diorite can be effectively destroyed under microwave irradiation

High-resolution sea-level fluctuations during the Mid-Holocene in the Ningshao Coastal Plain region, eastern China

Sea level changes during the Mid-Holocene directly influenced the Neolithic culture in the Yangtze River Delta region (YRD). However, the high-resolution sea level change characteristics for this period remain unclear. In this study, we performed a high-resolution palynological analysis, including pollen, Dinoflagellate cysts, and Foraminiferal organic linings, using a high-resolution sediment core from Shanglin Lake, in the North of Ningshao Plain (the south of Hangzhou Bay). 11 accelerator mass spectrometry 14C(AMS) datings indicate the age of the sediments range from 8 cal ka B.P. to 5.6 cal ka B.P. The results show that during the Mid-Holocene, Shanglin Lake evolved from an estuary – subtidal lagoon – semi-enclosed bay – semi-enclosed lagoon – semi-enclosed bay – enclosed lagoon to a modern freshwater lake. There was a period of no, or minimal, eustatic sea-level rise between 7733 and 7585 cal yr B.P. The Mid-Holocene high sea level comes in 7253–7082 cal yr BP. Between 7000 cal yr BP and 5502 cal yr BP, the sea level is close to modern value. The sea level change during this period had a significant impact on the local Neolithic human activity

Effect of substituting IPV for tOPV on immunity to poliovirus in Bangladeshi infants: An open-label randomized controlled trial

AbstractBackgroundThe Polio Endgame strategy includes phased withdrawal of oral poliovirus vaccines (OPV) coordinated with introduction of inactivated poliovirus vaccine (IPV) to ensure population immunity. The impact of IPV introduction into a primary OPV series of immunizations in a developing country is uncertain.MethodsBetween May 2011 and November 2012, we enrolled 700 Bangladeshi infant-mother dyads from Dhaka slums into an open-label randomized controlled trial to test whether substituting an injected IPV dose for the standard Expanded Program on Immunization (EPI) fourth tOPV dose at infant age 39 weeks would reduce fecal shedding and enhance systemic immunity. The primary endpoint was mucosal immunity to poliovirus at age one year, measured by fecal excretion of any Sabin virus at five time points up to 25 days post-52 week tOPV challenge, analyzed by the intention to treat principle.FindingsWe randomized 350 families to the tOPV and IPV vaccination arms. Neither study arm resulted in superior intestinal protection at 52 weeks measured by the prevalence of infants shedding any of three poliovirus serotypes, but the IPV dose induced significantly higher seroprevalence and seroconversion rates. This result was identical for poliovirus detection by cell culture or RT-qPCR. The non-significant estimated culture-based shedding risk difference was −3% favoring IPV, and the two vaccination schedules were inferred to be equivalent within a 95% confidence margin of −10% to +4%. Results for shedding analyses stratified by poliovirus type were similar.ConclusionsNeither of the vaccination regimens is superior to the other in enhancing intestinal immunity as measured by poliovirus shedding at 52 weeks of age and the IPV regimen provides similar intestinal immunity to the four tOPV series, although the IPV regimen strongly enhances humoral immunity. The IPV-modified regimen may be considered for vaccination programs without loss of intestinal protection