User Follow Prediction of Microblog Based on the Activeness and Interest Similarity

Many microblog fans have formed the basis of microblog information dissemination and diffusion, so accurate prediction and attracting more potential customers to follow microblogger becomes very necessary. By employing interpersonal relationship network of microblog fans, this study integrates microblogger popularity and user activeness into interest similarity in order to explain user follow predictor and propose user follow prediction models. Support vector machine (SVM) is used to train this model. Open data from Tencent microblog in KDD Cup 2012 prove that the proposed prediction model has higher prediction accuracy and stability. Key words: Microblog; User follow; Microblogger popularity; User activeness; Interest similarity; Prediction mode

The prognostic value of detection of serum VEGF-C level and lymphangiogenesis in mediastinal lymph nodes in the patients with lung cancer

Background and objective There is still lack of special prognostic factor on lung cancer, this study will explore the prognostic value of serum VEGF-C level and lymphangiogenesis of primary cancer and mediastinal lymph nodes in the patients with lung cancer. Methods Thirty patients with NSCLC would accept operation (new group) and 30cases followed up three years postoperative (history group) were chosen respectively. The serum VEGF-C level of new group was tested. The VEGF-C and LYVE-1 expression in the mediastinal lymph nodes were put in practice between two groups. The relationship was analyzed for the serum VEGF-C level, VEGF-C and LYVE-1 expression of primary cancerand mediastinal lymph nodes, mediastinal lymph nodes metastasis and the 3-year survival rate of the patients. Results ①In new group, the serum VEGF-C level of N2 patients was significantly higher than that of non-N2 patients. ②In new group, the serum VEGF-C level was closely correlated with VEGF-C expression of primary cancer. ③In two groups, the primary cancer and mediastinal metastasis lymph nodes had high VEGF-C expression. ④VEGF-C expression of primary cancer and mediastinal lymph nodes was closely correlated with LYVE-1 expression between the two groups. ⑤VEGF-C and LYVE-1 expression of N2 patients was significantly higher than that of non-N2 patients between two groups. ⑥The patients' 3-year-survival rate was closely correlated with VEGF-C expression of primary cancer and mediastinal lymphnodes metastasis. Conclusion Serum VEGF-C level has close correlation with VEGF-C expression of primary cancer, lymphangiogenesis of primary cancer/mediastinal lymph nodes, mediastinal lymph nodes metastasis status and patient's survival rate. Serum VEGF-C level is possible to be used as prognostic factor on lung cancer

Effects of MVP regimen on operation and cancer tisswes of Lung Cancer patients

Background and objective Preoperative chemotherapy increases the difficulty and risk of patients爷operation. The aim of this study is to analyze the change of thoracic tissue, study the influence ofchemotherapy to operation, discuss the special aspects of surgical management and observe the pathological change of focus after chemotherapy. Methods 100 patients were chosen and randomly divided into two groups(operation first group, 50 cases; chemotherapy first group, 50 cases) . Some patient爷s pathological sections were observed to investigate focus morphological influence of preoperative chemotherapy and the clinical response rate were compared with pathological response rate. Results It was showed that preoperative chemotherapy conduced different degree thoracic tissue fibrosis. Data statistics demonstrated that there were no significance difference of the operation time, blood loss during operation and drainage volume in first day after operation between two groups. The preoperativechemotherapy increased the difficulty of operation because of tissue fibrosis and scarification, but the risk could be avoided by skillful operation. In first operation group, there were various pathological changes in tumor tissue and the pathological response rate was not completely accordance with the clinical response rate. The focus pathological response rate of two cycles chemotherapy was more higher than that of one cycle chemotherapy. Conclusion Chemotherapy increases the risks of operation. Surgeons carefulness and better skills during operation are the key points to avoid the hazards of surgery. Two preoperative chemotherapy cycles are more suitable for the patients

Effects of pulmonary veins ligation style for the patients' stress and cardiac on lung cancer

Background and objective It is needed to explore the effects of operation on stress statue, myocardial damage and arrhythmia to lung cancer. This study would compare the effects of two ligation styles of pulmonary vein on lung cancer patients' stress and cardiac postoperative. Methods 54 cases were divided into two groups randomly:the pulmonary vein trunk-ligation group (trunk group, 27 cases) and the pulmonary vein branch-ligation group (branch group, 27 cases). The blood concentrations of hydrocortisone (HC), blood glucose (BG) and cardial troponin-I (cTnI) were determined at different time point. The surgical data, the quantum of pain and ECG also recorded. Results ① There were no significance difference of the operation time, blood loss during operation and drainage volume in first day after operation between two groups. ② There're no differences of the quantum of pain between two groups. ③ The HC of the two groups' ascend obviously on the end of operation and descend during postoperative. ④ The BG of the two groups' rise on the 1st day obviously, maintain high level on the 2nd day, descend on the 3rd day but still higher than that of preoperation.⑤ The BG and HC show a direct positive correlation postoperative. ⑥ The cTnIs of the trunk group ascend immediatelyafter operation, but there's no statistically significance between two groups. ⑦ The arrhythmia incidence is higher in the trunk group, but the arrhythmia incidences classified by the date after operation of the two groups' show no distinction. Conclusion ① The effects of two pulmonary vein ligation styles on postoperative stress show no significance differences.② The style of pulmonary vein trunk-ligation has a more obvious tendency to do harm to heart than that of branch-ligation. ③ The style of pulmonary vein branch-ligation may reduce the arrhythmia incidence after operation

Study on the Prognosis of the T1a Non-small Cell Lung Cancer

Background and objective The new edition of the TNM staging for lung and pleural tumours has been finished, which put weight on the extent of primary tumor as one of the important prognosises. But little study has performed on the primary tumor extent ≤2 cm. The aim of this study is to explore the prognosis of patients with tumor extent ≤2 cm in stage I of non-small cell lung cancer, which helps us to choose the best treatment for these patients. Methods Retrospective study on the clinical response and survival time of whom underwent complete surgical resection and diagnosed as T1a of stage I NSCLC from 1998 to 2004 was analyzed. Data was analyzed by SPSS 17.0 software. Results Overall survival rate was 80.8%. By the study, age (P=0.241), gender (P=0.175), history of smoking (P=0.845), pathologic type (P=0.265), and systematic mediastinal lymphadenectomy (SML)(P=0.918) or not, postoperative adjuvant chemotherapy or not (P=0.616) and visceral pleural invasion (P=0.827) were not the prognosises of these patients. Only the tumor differentiation such as poorly differentiated was the important prognosis (P=0.01). Conclusion In the tumor extent ≤2 cm of stage I non-small cell lung cancer, the visceral pleural invasion maybe not influence the patients survival. The tumor differentiation is one of the important prognostic factors