Mesoporous Zirconium Phosphonate Hybrid Material as Adsorbent to Heavy Metal Ions

A new kind of inorganic–organic hybrid zirconium phosphonate material (NTAZP) with mesoporous structure was synthesized using nitrilotris­(methylene)-triphosphonic acid (ATMP) and zirconium dichloride oxide octahydrate. The sample possesses a spherical morphology, and the spheres are composed of lobular lamellae. The lobular lamellae have the structure of a worm-like mesoporous (about 2.7 nm) framework and a high surface area (about 160.4 m²/g), which were characterized by SEM, TEM, N₂ sorption, XRD, TG-DTA, elemental analysis, TOC (total organic carbon), XPS, and FT-IR spectroscopy techniques. The as-prepared NTAZP was used as adsorbent for the efficient removal of heavy metal ions (e.g., Pb²⁺, Cu²⁺, and Cd²⁺). Our results indicate that the material has good prospects for application as an adsorbent in wastewater processing

Additional file 1 of Monocytes reprogrammed by tumor microparticle vaccine inhibit tumorigenesis and tumor development

Additional file 1: Fig. S1. Intramuscular injection of B16-MPs inhibited tumorigenesis of B16-F10 melanoma. Fig. S2. Intramuscular inoculation of MPs from CT26 colon carcinoma cells rather than those from H22 hepatocarcinoma cells led to prevention of CT26 tumor growth. Fig. S3. T-MPs as a tumor vaccine presented a good safety. Fig. S4. B lymphocytes and T lymphocytes in BALB/c mice don't endocytose T-MPs. Fig. S5. T-MPs are mainly endocytosed by monocytes and macrophages in C57BL/6 mice. Fig. S6. T-MPs treatment doesn't cause the proliferation of moDCs in the dLN. Fig. S7. DNAs and RNAs were isolated from T-MPs